Reposted by Themistoklis Paraschiakos
How do hundreds of proteins grip the cell’s actin skeleton? After 4 years of work, we discovered a tiny, 9-amino-acid conserved motif that acts as a universal molecular anchor—defining a whole new class of actin-binding proteins! Read it here: www.nature.com/articles/s41...
nature.com
Evolutionarily conserved short linear motifs drive actin filament binding - Nature Cell Biology
Paraschiakos, Yuan et al., using a computational pipeline, identify the short linear actin filament-binding motif (SFM) as an evolutionarily conserved actin filament-binding motif present in 103 human...