Reposted by Debabrata LahaLorraine Reese @lorraine-reese.bsky.social · 11/08/2026If you're interested in our 'Inositol Phosphate and Pyrophosphate Signalling' meeting (abstract deadline Thursday!), you may be interested in these related articles from our journals 🧪 bit.ly/4xsXIfW 021
Reposted by Debabrata LahaLorraine Reese @lorraine-reese.bsky.social · 10/07/2026Join @blindlab.bsky.social, @structplantbio.bsky.social, @thelahalab.bsky.social and many others at Inositol Phosphate and Pyrophosphate Signalling in October, in the beautiful medieval city of York 🧪 bit.ly/4p16yP3 022
Reposted by Debabrata LahaGabriel Schaaf @gabrielschaaf.bsky.social · 23/05/2026I am happy to share that the final version of our review on Metabolism, Perception, and Functions of Inositol (Pyro)Phosphates in Plants has been published. Many thanks to Ricardo Giehl @leibnizipk.bsky.social for this great collaboration - www.annualreviews.org/content/jour...annualreviews.orgMetabolism, Perception, and Functions of Inositol (Pyro)Phosphates in PlantsInositol phosphates and pyrophosphates are small, water-soluble molecules involved in a range of physiological processes across eukaryotic organisms, including plants. Over the past two decades, signi... 095
Reposted by Debabrata LahaMartina Ried-Lasi @martinaried.bsky.social · 22/05/2026Deeply grateful to all co-authors for their contributions, especially Henning Jessen @jessenlab.bsky.social and Dorothea Fiedler for bringing their fantastic expertise to this project. Very happy to see this story published! 033
Debabrata Laha @thelahalab.bsky.social · 23/05/2026Nice piece of work. Congratulations to Gabriel, Martina and entire team! 020
Reposted by Debabrata LahaHenning Jessen @jessenlab.bsky.social · 02/03/2026interested in inositol pyrophosphate interactors in plants? here is a complete list based on photoaffinity pulldown. congrats to Kevin and many thanks to all fantastic collaborators. advanced.onlinelibrary.wiley.com/doi/10.1002/...advanced.onlinelibrary.wiley.comAffinity‐Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6‐PP‐InsP5‐Binding Proteins in PlantsInositol pyrophosphates (PP-InsPs) are central regulators of eukaryotic signaling events. While certain PP-InsP isomers have been conclusively linked to the regulation of phosphate homeostasis throug... 0134
Reposted by Debabrata LahaHenning Jessen @jessenlab.bsky.social · 28/02/2026onlinelibrary.wiley.com/doi/10.1002/... Caged Magic Spot Nucleotides with 4 or 5 phosphates can now be delivered into living E coli cells and be released with light on demand. Congratulations to Christoph Popp for all the great work.onlinelibrary.wiley.com 073
Reposted by Debabrata LahaAgrisera antibodies @agrisera.bsky.social · 11/12/2025In celebration of Agrisera’s 40th anniversary, we have conducted a series of short interviews with scientists, who have supported the development of Agrisera's antibody collection. Read full interview with Assistant Prof. Debabrata Laha: www.agrisera.com/en/Agrisera-... 021
Debabrata Laha @thelahalab.bsky.social · 25/11/2025The expanding landscape of inositol phosphate signaling network in land plants - Ghosh - FEBS Letters - Wiley Online Library febs.onlinelibrary.wiley.com/doi/10.1002/... 031
Reposted by Debabrata LahaNature Chemical Biology @natchembio.nature.com · 31/10/2025Our November issue is live! www.nature.com/nchembio/vol... The cover depicts a SEM image of a dorsal surface of liverwort M. polymorpha female thallus. Liverwort were found to have a noncanonical pathway for the regulation of master growth repressor DELLA. 051
Debabrata Laha @thelahalab.bsky.social · 31/10/2025Really delighted and humbled to see that we made it into cover! This is first time for us. Please see more details about work in PMID: 40745478. 000
Debabrata Laha @thelahalab.bsky.social · 11/09/2025Happy to share our work on identification of non-archetypal activity of IPK2 in producing inositol pyrophosphate 4/6-IP7 and regulating heat stress acclimation-conserved in studied land plants. Grateful to @jessenlab.bsky.social for wonderful collaborative efforts! journals.plos.org/plosgenetics...journals.plos.orgConservation of heat stress acclimation by the IPK2-type kinases that control the synthesis of the inositol pyrophosphate 4/6-InsP7 in land plantsAuthor summary Inositol pyrophosphates (PP-InsPs) are eukaryote-specific cellular messengers that control a plethora of critical physiological processes, ranging from cellular metabolism to cellular e... 174
Debabrata Laha @thelahalab.bsky.social · 31/07/2025Delighted to share our work "GA-independent DELLA regulation by pyrophosphate in a nonvascular land plant" published now in Nature Chemical Biology! @natchembio.nature.com www.nature.com/articles/s41...nature.comGA-independent DELLA regulation by inositol pyrophosphate in a nonvascular land plant - Nature Chemical BiologyA noncanonical pathway of DELLA regulation by a conserved inositol pyrophosphate synthase was identified in the liverwort, Marchantia polymorpha, that lacks the canonical gibberellin-induced DELLA deg... 072
Reposted by Debabrata LahaHenning Jessen @jessenlab.bsky.social · 01/07/2025congrats to Kevin! His paper on new inositol pyrophosphates is out in @angewandtechemie.bsky.social doi.org/10.1002/anie...doi.orgExpanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP‐InsP4 Isomers in Plant SignalingInositol pyrophosphates (PP-InsPs) are highly phosphorylated signaling molecules that regulate diverse cellular processes, including phosphate homeostasis and energy metabolism across species. Despit... 2102
Reposted by Debabrata LahaHenning Jessen @jessenlab.bsky.social · 18/04/2025An alternative strategy to access inositol derivatives by stereoselective dephosphorylation. Happy to share the work by Markus Haener together with @gabrielschaaf.bsky.social and many others. chemrxiv.org/engage/chemr...chemrxiv.orgStereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivativesPhosphorylated myo-inositols (InsPs) are essential cytoplasmic signaling molecules, while their lipidated analogs (PtdInsPs) play a crucial role in membrane signaling. Stereoselective synthesis of the... 043
Reposted by Debabrata LahaHiro Nakagami @grandpahiro.bsky.social · 17/04/2025The final version of our study on SERK-BIR module in Marchantia is out. Congratulations Cate and many thanks to collaborators! www.sciencedirect.com/science/arti...sciencedirect.comConserved role of the SERK-BIR module in development and immunity across land plantsSOMATIC EMBRYOGENESIS RECEPTOR-LIKE KINASES (SERKs), which are subfamily II of leucine-rich repeat receptor-like kinases (LRR-RLKs), play diverse role… 75227
Reposted by Debabrata LahaHenning Jessen @jessenlab.bsky.social · 28/03/2025Happy to share Kevin´s great work on PP-InsP4 synthesis and analysis now available on Chemrxiv! chemrxiv.org/engage/chemr...chemrxiv.orgExpanding the PP-INSP₄ Toolbox: Synthesis, Stereochemical Assignment, and Application in Plant Phosphate SignalingInositol pyrophosphates (PP-InsPs) are highly phosphorylated signaling molecules that regulate diverse cellular processes, including phosphate homeostasis and energy metabolism across species. Despite... 041