iiinova — where your digital self keeps evolving

Reposted by Emmanuel Crespo

Konrad Kording @kordinglab.bsky.social · 16/12/2024

There was this Tsai/Yuste/Shepard paper that meister famously eviscerated. markusmeister.com/2018/03/20/d... It seems that the authors never retracted the paper (or does ieee not mark retractions)? If not, does anyone know why not? @retractionwatch.com

markusmeister.com

Death of the sampling theorem?

tl;dr: A team from Columbia University led by Ken Shepard and Rafa Yuste claims to beat the 100 year old Sampling Theorem [1,2]. Apparently anti-aliasing filters are superfluous now because one can…

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Emmanuel Crespo @theglowup.bsky.social · 27/11/2024

Me: confident in surgery. Mouse brain, three weeks later: ‘Sure, bud’. 😊🧠🥲

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Reposted by Emmanuel Crespo

Katharina Schmack @kathaschmack.bsky.social · 27/11/2024

Mouse stereotactic surgery never gets old: you level a tiny irregular skull, go by coordinates based on eyeballed reference points, deliver microdrops of virus following protocolised superstition and whoom, three weeks later, the exact subregion you aimed for lights up (well, sometimes) ✨🧠🧪

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Reposted by Emmanuel Crespo

Zero-Noise Lab @zeronoiselab.bsky.social · 26/11/2024

This shows that we need to apply averages carefully because they mean different things in different experimental contexts. In other words - THINK BEFORE YOUR AVERAGE! And feel welcome to use our test to help you do that. ;) journals.plos.org/ploscompbiol...

journals.plos.org

What does the mean mean? A simple test for neuroscience

Author summary Neuronal activity is highly dynamic—our brain never responds to the same situation in exactly the same way. How do we extract information from such dynamic signals? The classical answer...

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Reposted by Emmanuel Crespo

Michael Kasten @madscientistphd.bsky.social · 23/11/2024

I usually focus on neurons that fire crazy fast, but I like neurons that burst, too!!

A bursty bursty cartwheel neuron firing like crazy in response to a depolarizing current injection.

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Reposted by Emmanuel Crespo

Ryan Hoffman, PhD @ryanthescientist.bsky.social · 22/11/2024

Happy #FluorescentFriday Here is a cerebral organoid expressing 5-HT2A receptors (red) along its outer surface. They seem to be a different set of cells than the CTIP2 positive deep layer neurons (magenta). There seems to be some believable 5-HT2C (green) signal basal to the rosettes too 🔬 #sciart

10 week old sliced immunohistological stain of a dorsal forebrain organoid. Stained for HTR2A in red, HTR2C in green (interior green looks non-specific), BCL11B in magenta, and DAPI in blue.

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Reposted by Emmanuel Crespo

Aitor Morales-Gregorio @aitormg.bsky.social · 13/11/2024

Felt a little extra today when preparing a spike sorting lecture and put together these illustrations, I could not find anything similar for single electrodes! 🧪🧠⚡ #neuroskyence #SciArt

Electrophysiology electrode surrounded by pyramidal neurons. The neuron waveforms are shown on top of each neuron, nearby neurons have larger waveforms and faraway neurons have very tiny waveforms.

Pyramidal neurons were modified from scidraw.io, Claudi, F. (2020). pyramidal neuron. Zenodo. https://doi.org/10.5281/zenodo.3925905)

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Reposted by Emmanuel Crespo

Aitor Morales-Gregorio @aitormg.bsky.social · 20/11/2024

If you are interested in neural manifolds, dimensionality, brain states, and/or top-down modulation you are gonna like this one! 🧠🙈💫🧪 "Neural manifolds in V1 change with top-down signals from V4 targeting the foveal region" doi.org/10.1016/j.ce... Also enjoy this animation :) #SciArt #neuroskyence

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