Visual motion can bias perceived orientation relative to gravity, raising the question of whether visual and vestibular signals are integrated within cerebellar circuits that encode self-motion. This ...

Stable gaze is essential for effective navigation, yet during locomotion each stride generates phasic head movements that can destabilize the visual scene. The vestibular system is well positioned to ...

The vestibular system of the inner ear provides head motion and orientation information required for maintaining balance and spatial orientation. E...

Celebrate the one-year anniversary of Canada Leads at UHN. Discover how this program is transforming research and attracting top scientists to Canada’s leading hospital.

Maintaining balance requires the nervous system to transform sensory signals about unexpected postural perturbations into precisely timed motor commands. Although human studies have established that p...

For more than 80 years, scientists believed bat eyes were static. Research from the Cullen Lab reveals the first direct evidence of bat eye movement and its critical role in navigation.

Chang et al. overturn an 80-year-old assumption by showing that echolocating bats make robust eye movements. Bats generate strong visually driven optokinetic and otolith-mediated responses but exhibit...

How the brain meets these competing demands–and where such a veridical “ground-truth” representation is computed–remains unknown. Here authors show that the cerebellar nodulus/uvula–a region essential...

Proper orientation of the apical cytoskeleton in auditory and vestibular hair cells is essential for their sensory function. A recently identified regulator of hair cell orientation is the G protein-c...

Background Falls are a leading cause of injury and loss of independence among older adults, yet comprehensive, population-level models that integrate diverse risk factors across broad demographic grou...

Scientific Reports - Superior canal dehiscence syndrome induces canal-specific kinematic adaptations during locomotion

Neuropixels (NP) probes [1], [2] are high-density, integrated silicon electrodes that can simultaneously record from 384 neural channels across up to 5120 sites. These high-resolution recording device...

The cerebellar vermis plays an essential role in maintaining posture and balance by integrating sensory inputs from multiple modalities to effectively coordinate movement. By transforming convergent s...

Falls are the leading cause of injury-related death among seniors in the United States. Johns Hopkins researcher Kathleen Cullen studies the vestibular system in our inner ear, integral to maintaining...

Scientific Reports - Vestibular patients generate more regular head movements than healthy individuals during gaze-stabilization exercises