Sign in

TF Stoop

@tfstoop.bsky.social
142 followers 117 following 15 posts

MD, PhD candidate HPB Surgery Amsterdam UMC 🇳🇱| Former Research Fellow Karolinska University Hospital 🇸🇪 & University of Colorado 🇺🇸

PostsRepliesMedia
Reposted by TF Stoop
Giovanni Marchegiani, MD PhD @gio-marchegiani.bsky.social · 11/09/2025
It’s out!!! 🔥🔥🔥 The PREOPANC-2 is in @thelancet.com Neoadjuvant FOLFIRINOX 🤜🤛 Gemcitabine based chemoradiotherapy in resecatble / BR ⚖️ No difference in overall survival 😰 Serious adverse events 40% 👍 Both regimens may be considered www.thelancet.com/pdfs/journal...
141
Reposted by TF Stoop
BJS @bjsurgery.bsky.social · 07/08/2025
This population-based study on the NCCN resectability stages of pancreatic adenocarcinoma indicates that the rate of LAPC was lower than reported in literature, whereas the rate of PRPC is higher
doi.org
Resectability stages of pancreatic cancer: nationwide reference
At diagnosis, pancreatic adenocarcinoma is categorized into resectability stages based on extent of vascular involvement and presence of metastases at cros
021
TF Stoop @tfstoop.bsky.social · 07/08/2025
Published in @bjsurgery.bsky.social, unique nationwide 🇳🇱 data @dpcgofficial.bsky.social on #NCCN resectability staging of #PancreaticCancer at diagnosis: 🧷 23% PRPC 🧷 8% BRPC 🧷 11% LAPC 🧷 58% M1 … including stratification for tumour location. 👉 academic.oup.com/bjs/article/...
021
Reposted by TF Stoop
IHPBA @ihpba.bsky.social · 29/07/2025
HPB Journal Highlight ⭐️Ishida et al. Global survey shows big variation in how surgeons manage neck of pancreas cancers, especially with vascular involvement. Highlights the need for future studies & clearer guidelines! 🔗https://tinyurl.com/3myun89t 📊🌎 #PancreaticCancer #HPBSurgery
041
Reposted by TF Stoop
Marc Besselink @marcbesselink.bsky.social · 11/07/2025
Distribution of the NCCN stages of #PancreaticCancer ? 16,412 pts (2017-2022) 🇳🇱 👉23% primary resectable 👉 8% borderline resectable 👉 11% locally advanced 👉 58% metastatic ⏩️ academic.oup.com/bjs/article/11…
064
TF Stoop @tfstoop.bsky.social · 07/05/2025
Published in #BJC, our 🌎 study with 935 localized #pancreaticancer patients after resection, comparing preoperative FFX vs GnP: 📎FFX vs GnP not associated with OS (p=0.17) 📎Effect FFX ⬆️ if lower serum CA19.9 #tumorbiology 🚨Pragmatic RCT #chemosensitivitymarkers🔍 👉 www.nature.com/articles/s41...
041
Reposted by TF Stoop
Marc Besselink @marcbesselink.bsky.social · 24/04/2025
Immensely honored to receive a Honorary Fellowship with #ASA #American #Surgical #Association #AnnalsOfSurgery in #SanDiego
021
Reposted by TF Stoop
The Lancet @thelancet.com · 24/04/2025
Pancreatic cancer, often linked to smoking, obesity and diabetes, is predicted to become the 2nd leading cause of cancer-related death by 2030. A recent Seminar discusses the need for novel therapies & future directions for research: tinyurl.com/ywue2nfs
Figure showing most common symptoms and signs of pancreatic cancer at diagnosis. Copyright: Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.
02114
TF Stoop @tfstoop.bsky.social · 05/04/2025
👉 www.thelancet.com/journals/lan... NB. Corrected version will be published next week.
thelancet.com
Lancet
000
TF Stoop @tfstoop.bsky.social · 05/04/2025
Published in @thelancet.bsky.social, our review on #PancreaticCancer 📎Epidemiology🌎 📎Pathogenesis🔬 📎Risk factors & surveillance🕵️ 📎Diagnostics🩺 📎Treatment💊 📎Future directions🔍 … by AA Javed, A Oba, T Seufferlein, JW Wilmink, @basgrootkoerkamp.bsky.social & @marcbesselink.bsky.social.
152
Reposted by TF Stoop
Marc Besselink @marcbesselink.bsky.social · 21/03/2025
Congrats to #AnoukEmmen and @tfstoop.bsky.social for excellent presentations in the #PresidentialSession #AHPBA2025 AHPBA Miami 🇺🇸: #DIPLOMA2 RCT🇪🇺 robot/lap 🤖 vs open Whipple and #PREOPANC4🇳🇱 implementation of surgery for locally advanced #PancreaticCancer for @dpcgofficial.bsky.social and #EMIPS
043
TF Stoop @tfstoop.bsky.social · 16/03/2025
👉 full text: www.sciencedirect.com/science/arti...
sciencedirect.com
000
TF Stoop @tfstoop.bsky.social · 16/03/2025
Published in #hpbjournal, 🌎 survey on surgical management of pancreatic neck/body cancer with venous involvement: 📝222 surgeons, 49 countries, 6 continents 📍Heterogeneity in surgical management➡️particularly when ⬆️ venous involvement ⚠️ Need for research 🔍 @eahpba.bsky.social @ihpba.bsky.social
101
Reposted by TF Stoop
Simone Augustinus @simoneaug.bsky.social · 22/02/2025
In JNCCN our nationwide study on quality of life in patients with locally advanced PDAC 🇳🇱 ⭐️ QoL remains stable over time, regardless of receiving treatment (89%) 😱 Symptoms significantly deteriorate and deserve attention ➡️ Use in shared decision making @dpcgofficial.bsky.social
141
TF Stoop @tfstoop.bsky.social · 19/02/2025
👉 full text: bmccancer.biomedcentral.com/articles/10....
bmccancer.biomedcentral.com
Nationwide implementation of the international multidisciplinary best-practice for locally advanced pancreatic cancer (PREOPANC-4): study protocol - BMC Cancer
Background The introduction of (m)FOLFIRINOX and gemcitabine-nab-paclitaxel has changed the perspective for patients with locally advanced pancreatic cancer (LAPC). Consequently, in experienced centre...
010
TF Stoop @tfstoop.bsky.social · 19/02/2025
In #BMC Cancer, #PREOPANC4 protocol to improve #LAPC care in 🇳🇱 @dpcgofficial.bsky.social with help of 4 international experts🇩🇪🇺🇸: 📎Multidisciplinary & surgical training program 📎Structured induction therapy, response evaluation & selection for surgery 📎National expertpanel 📎Patient-centered care
252
Reposted by TF Stoop
Julia Menso @juliamenso.bsky.social · 02/02/2025
Looking back at an incredible #ALPS2025 meeting and delighted to have been awarded the Best Mini-Oral Presentation for our cost-analysis of robot vs open Whipple! Many thanks to the @amsterdamumc.bsky.social HPB-team @MichielFrancken @marcbesselink.bsky.social #roboticsurgery #pancreas
041
Reposted by TF Stoop
BJS @bjsurgery.bsky.social · 02/02/2025
Preoperative stereotactic radiotherapy to prevent pancreatic fistula in high-risk patients undergoing pancreatoduodenectomy (FIBROPANC): prospective multicentre phase II single-arm trial ➡️ doi.org/10.1093/bjs/...
doi.org
Preoperative stereotactic radiotherapy to prevent pancreatic fistula in high-risk patients undergoing pancreatoduodenectomy (FIBROPANC): prospective multicentre phase II single-arm trial
The FIBROPANC study investigated the safety, feasibility, and efficacy of preoperative stereotactic radiotherapy on the pancreatic neck transection margin
465
Reposted by TF Stoop
Marc Besselink @marcbesselink.bsky.social · 01/02/2025
Can prophylactic #Radiotherapy #SBRT in non-PDAC #pancreatoduodenectomy prevent fistula POPF? 🔑 “it works but doesn’t help” ▶️#FIBROPANC published today @bjsurgery.bsky.social @dpcgofficial.bsky.social @eahpba.bsky.social @ihpba.bsky.social academic.oup.com/bjs/article/...
082
TF Stoop @tfstoop.bsky.social · 23/01/2025
Full text here 👉🏼 jamanetwork.com/journals/jam...
jamanetwork.com
Adjuvant Chemotherapy After Resection of Pancreatic Adenocarcinoma Following Preoperative FOLFIRINOX
This cohort study investigates the association of adjuvant chemotherapy following resection of pancreatic adenocarcinoma after preoperative FOLFIRINOX in full or modified dosing with overall survival,...
031
TF Stoop @tfstoop.bsky.social · 23/01/2025
In JAMA Oncology our 🌎 @eahpba.bsky.social study on adjuvant chemo (AT) in 742 resected localized #PDAC patients following NAT #FFX (40 centers): 📌OS ⬆️ by AT; … only with multi-agent AT ⚠️ 📌Possibly less effect of AT if >=8c NAT FFX, RECIST response, ypN0 & head tumor 📣 📯RCT🟰🔑
142
TF Stoop @tfstoop.bsky.social · 23/01/2025
👉🏼 full text here: journals.lww.com/annalsofsurg...
journals.lww.com
Tangential Versus Segmental Portomesenteric Venous... : Annals of Surgery
mparative studies on tangential versus segmental PVR as part of pancreatoduodenectomy for pancreatic cancer include all degrees of PMV involvement, including cases where tangential PVR may not be a fe...
010
TF Stoop @tfstoop.bsky.social · 23/01/2025
PVR 1-2 vs 3-4 during pancreatoduodenectomy for resectable #PDAC with venous involvement? In Annals of Surgery, our observational study with 357 patients from 🇸🇪🇯🇵🇳🇱🇺🇸: 📌PVR type NOT associated with OS, locoregional recurrence & major morbidity ➡️ surgeon’s personal preference
152
Reposted by TF Stoop
Giovanni Marchegiani, MD PhD @gio-marchegiani.bsky.social · 17/01/2025
Neoadjuvant chemotherapy for left 👈 sided resectable #PDAC 🪡 72% of US received adjuvant 💉 NAT had better OS (53 🆚 37 months) 🤏 Tumor size and 🧪 elevated CA19.9 correlates with benefits of NAT And now… time for RCT! 💪 #HPBSky www.annalsofoncology.org/article/S092...
084
TF Stoop @tfstoop.bsky.social · 13/01/2025
www.annalsofoncology.org/article/S092...
annalsofoncology.org
The impact of neoadjuvant therapy in patients with left-sided resectable pancreatic cancer: an international multicenter study
To assess the association between neoadjuvant therapy and overall survival (OS) in patients with left-sided resectable pancreatic cancer (RPC) compared to upfront surgery.
032
TF Stoop @tfstoop.bsky.social · 13/01/2025
NAT for left-sided RPC? In Annals of Oncology our 🌎 observational study on #NAT vs #US in 2282 patients with resected left-sided #RPC (76 centers): 📌OS⬆️after NAT vs US … 5y OS 47% vs 35% 📌NAT effect⬆️in large tumors & higher CA19.9 at diagnosis 🔑🟰ABC-approach 📯RCT See full text below 👇
131
Reposted by TF Stoop
Giovanni Marchegiani, MD PhD @gio-marchegiani.bsky.social · 19/11/2024
Perioperative therapy for #Pancreas Cancer ⭐️ A stellar lecture by the great Matthew H Katz 🇺🇸 @mdanderson.bsky.social ⭐️ All you need to know, and future perspectives in the eyes of a true pioneer of neoadjuvant chemo #HPBSky #SurgSky #MedSky youtube.com/watch?v=kIlH...
1174
Reposted by TF Stoop
Marc Besselink @marcbesselink.bsky.social · 03/12/2024
2025 Multi-Societal #European #Guideline on #PancreaticCancer ✅ Meeting with our 39 amazing Research leads to discuss group progress and any issues ▶️ 30 Societies ▶️ 13 Working groups ▶️ Focus on knowledge gaps @eahpba.bsky.social Laura Leeuwenburgh, Magdalena Holze, Elena Rangelova
192
TF Stoop @tfstoop.bsky.social · 01/12/2024
Hypothesizing paper @karolinskainst.bsky.social on POPF grade C management including early vs late rescue pancreatectomy: link.springer.com/article/10.1... Challenging #patientselection ⚖️ step-up approach PORSCH trial #DPCG
link.springer.com
Surgical management of severe pancreatic fistula after pancreatoduodenectomy: a comparison of early versus late rescue pancreatectomy - Langenbeck's Archives of Surgery
Background Rescue pancreatectomy for postoperative pancreatic fistula (POPF) after pancreatoduodenectomy (PD) is associated with high mortality. However, in-depth literature is scarce and hard to inte...
020