Very proud to share the first preprint from the Sheahan Lab, where we answer, ‘How does the kappa opioid system influence pain in the spinal cord?’
www.biorxiv.org/content/10.6...
biorxiv.org
Kappa opioid receptors in excitatory spinal neurons gate acute pain: evidence from mouse and human
The kappa opioid receptor (KOR) has emerged as a promising, nonaddictive analgesic target, yet the neural mechanisms underlying KOR inhibition of pain are not entirely understood. Here, we provide con...