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Tatsuo Fukagawa

@tatsuofukagawa.bsky.social

75 followers 5 following 3 posts

Cell Biologist, Centromere, Kinetochore

Posts Replies Media

Reposted by Tatsuo Fukagawa

The EMBO Journal @embojournal.org · 12/01/2026

Diversity in mechanisms for epigenetic specification of vertebrate centromeres: Tetsuya Hori, @tatsuofukagawa.bsky.social et al show that HJURP-dependent CENP-A deposition in chicken DT40 cells requires both Mis18 complex and CENP-C link.springer.com/article/10.1...

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Tatsuo Fukagawa @tatsuofukagawa.bsky.social · 08/01/2026

Our renent paper on CENP-A deposition was just out in EMBO J. Please check it out. Congrats Tetsuta! link.springer.com/article/10.1...

link.springer.com

Dual pathways via CENP-C and Mis18C recruit HJURP for CENP-A deposition into vertebrate centromeres - The EMBO Journal

Centromere position is specified and maintained by sequence-independent epigenetic mechanisms in vertebrate cells, with the incorporation of the centromere-specific histone H3 variant CENP-A into chro...

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Reposted by Tatsuo Fukagawa

Bungo Akiyoshi @bungoakiyoshi.bsky.social · 22/12/2025

Put together by Simona Giunta, @tatsuofukagawa.bsky.social, @roneilllab.bsky.social and myself. Big thanks to all the authors who contributed to this collection! link.springer.com/article/10.1...

link.springer.com

40 years of CENP-A: the foundation of a new era of centromere biology - Chromosome Research

Chromosome Research -

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Tatsuo Fukagawa @tatsuofukagawa.bsky.social · 10/11/2025

Our new paper was just out. CRISPR screening with a CENP-C mutant reveals that KIF18A and CENP-E are coordinately involved in chromosome congression. We also find that cancer cells with low levels of CENP-E are sensitive for KIF18A inhibition. Congrats Jiahang Miao! www.cell.com/cell-reports...

cell.com

KIF18A promotes chromosome congression in cooperation with CENP-E downstream of CENP-C

Miao et al. demonstrate that KIF18A depletion causes synthetic defects with CENP-C hypomorphic mutant and KIF18A functions for chromosome congression in cooperation with CENP-E. CENP-E levels at kinet...

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Tatsuo Fukagawa @tatsuofukagawa.bsky.social · 03/12/2024

I just started Bluesky.

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