Reposted by Tata lab @ Duke
An early holiday present from the @MorriseyLab! A story of stem cell collision/competition driving lung regeneration. A tour de force by Dakota…#WhyWeScience!
www.science.org/doi/10.1126/...
science.org
An injury-induced mesenchymal-epithelial cell niche coordinates regenerative responses in the lung
Severe lung injury causes airway basal stem cells to migrate and outcompete alveolar stem cells, resulting in dysplastic repair. We found that this “stem cell collision” generates an injury-induced ti...