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tabdanov.bsky.social

@tabdanov.bsky.social

109 followers 250 following 11 posts

Assistant Professor, The Pennsylvania State University, Department of Cell and Biological Systems, Hershey, PA

Posts Replies Media

tabdanov.bsky.social @tabdanov.bsky.social · 26/09/2026

#FluorescenceFriday

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tabdanov.bsky.social @tabdanov.bsky.social · 18/08/2026

#Septin as an environment-sensing system reads #Tcell deformations (#proprioceptor, #mechanosensor) caused by the ECM. In response, it condenses non-contractile, non-stretchable cortical rings to guide T cell's #amoeboid peristalsis in 3D ECM. science.org/doi/full/10....

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tabdanov.bsky.social @tabdanov.bsky.social · 18/08/2026

BTW, the #nucleus in our #lymphocytes i.e., #T-cells is mostly a topological donut (torus), with #microtubules wrapped around its surface nicely.

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tabdanov.bsky.social @tabdanov.bsky.social · 06/07/2026

#Dynein, not #myosin drives #T-cell #nucleokinesis by sliding #microtubules and the #nucleus along an F-actin fulcrum. Cyclic oscillations generate stride-wise migration, while modeling reveals that this behavior emerges from simple self-organization. www.biorxiv.org/content/10.6...

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tabdanov.bsky.social @tabdanov.bsky.social · 16/05/2026

Old, but gold. #Tcells often form tentacles to recognize their #antigens. And the resulting #lymphocyte's #immune #synapse is a dynamically unfolding spiral around #TCR microclusters. academic.oup.com/ib/article/7...

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tabdanov.bsky.social @tabdanov.bsky.social · 19/01/2026

Environments can induce cell structural instability, resulting in cell fragments shedding that can actively migrate, as described by as #Blebbisomes, or, as some decided to go more Hollywood with the terms, #Zombosomes.

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tabdanov.bsky.social @tabdanov.bsky.social · 08/10/2025

Gemini image editing is quite impressive……

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tabdanov.bsky.social @tabdanov.bsky.social · 09/09/2025

Just posted (bioRxiv): A novel #mechanobiology model revealing how #immune #Tcells combine a #nucleus as a #piston, an #uropod, and #microenvironment to power #amoeboid #cellmigration in #cellconfinement via a hydraulic cell engine. #CellBiophysics #ImmuneMigration www.biorxiv.org/content/10.1...

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