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Kenji Sugioka

@sugi05.bsky.social
73 followers 160 following 12 posts

Cell and developmental biologist / Studying developmental control of cell division using C. elegans. UBC Vancouver www.zoology.ubc.ca/~sugioka

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Reposted by Kenji Sugioka
Sue Biggins @suebiggins.bsky.social · 18/08/2026
Junior faculty position in Basic Sciences @fredhutch.org! Please repost!
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Reposted by Kenji Sugioka
Alex Eve @amjeve.uk · 26/07/2026
Chirality (handedness) is found across life. Nematode worms form chirality early, as cells divide in a spiral pattern. @sugi05.bsky.social shows how cells roll using intercellular scaffolds, axis tilts and cell-substrate adhesion via finger-like filopodia to direct clockwise cell division. #2026SDB
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Reposted by Kenji Sugioka
HItoshi Sawa @uncnondpy.bsky.social · 28/05/2026
Worm folks, mark your calendar for International worm meeting in Kobe Japan, July 18-22, 2027.
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Kenji Sugioka @sugi05.bsky.social · 26/05/2026
Tagging the UBC link: ubc.wd10.myworkdayjobs.com/en-US/ubcfac...
ubc.wd10.myworkdayjobs.com
Postdoctoral Research Fellow
Academic Job Category Faculty Non Bargaining Job Title Postdoctoral Research Fellow Department Research | Sugioka | Department of Zoology (Kenji Sugioka) Posting End Date June 18, 2026 Note: Applicati...
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Kenji Sugioka @sugi05.bsky.social · 26/05/2026
One month left to apply for this postdoc position in my lab at UBC! Funding is available for up to five years #DevBio #cellbio
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Reposted by Kenji Sugioka
Mélanie Laurin @melanielaurin.bsky.social · 22/05/2026
SAVE THE DATE for the 13th Canadian Developmental Biology Conference — March 7–10, 2027 — bringing together researchers, trainees, and innovators in developmental biology from across Canada and beyond.
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Kenji Sugioka @sugi05.bsky.social · 15/05/2026
(the paper also shows that I’m still not useless at the bench.) I was tasked the last experiment which was inspired by Yukinobu Arata-san’s work (Development 2010) from the Sawa lab @uncnondpy.bsky.social
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Kenji Sugioka @sugi05.bsky.social · 15/05/2026
Very insightful work from the Goehring lab on the control of cell polarity tunability during development! Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues | Science Advances www.science.org/doi/10.1126/...
science.org
Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues
Regulation of PAR network feedback by CDK-1 dynamically optimizes a sensitivity-stability trade-off during development.
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Kenji Sugioka @sugi05.bsky.social · 21/11/2025
Just got what felt like my first generative AI reviewer at one of respected Cell Bio journals. Declined to revise (lost interest in this journal) and submitted to Genetics right away
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Kenji Sugioka @sugi05.bsky.social · 22/10/2025
Adding another link. www.cell.com/current-biol... #Devbio
cell.com
Cadherin flow translates cortical chirality into left-right asymmetric cell division dynamics in Caenorhabditis elegans embryos
Khor et al. show that cadherin, a major adhesion molecule in animals, undergoes sequential polarized flows in Caenorhabditis elegans embryos. These flows establish a chiral cell-cell adhesion pattern ...
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Kenji Sugioka @sugi05.bsky.social · 22/10/2025
The work was spearheaded by MSc student Mi Jing Khor, with support from PhD candidate Yuxuan Rain Xiong and undergrad Gagan Sangha.
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Kenji Sugioka @sugi05.bsky.social · 22/10/2025
The established chiral cadherin patch interacts asymmetrically with the contractile ring, likely driving its rightward closure, the first detectable left–right asymmetry in C. elegans.
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Kenji Sugioka @sugi05.bsky.social · 22/10/2025
We showed that both ventral and left–right asymmetric cadherin flows are required to generate a chiral cadherin patch pattern.
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Kenji Sugioka @sugi05.bsky.social · 22/10/2025
We found that cadherin at cell–cell contacts exhibits two distinct flows, such as ventral flow and left–right asymmetric flow, each driven by ECM and RhoA signaling (left movie). The resulting cadherin patch pattern is chiral, meaning it cannot be superimposed on its mirror image
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Kenji Sugioka @sugi05.bsky.social · 22/10/2025
We used the 2nd mitosis of C. elegans as a model system, which shows both chiral cortical dynamics and L-R asymmetric closure of the contractile ring. Our past study shows that cell adhesion drives asymmetric ring closure in this cell type. www.nature.com/articles/s41...
nature.com
Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis - Nature Communications
Contractile ring formation, positioning, and closure is influenced by tissue mechanics, though how this information is transmitted is unclear. Here they show that Anillin is critical for a mechanosens...
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Kenji Sugioka @sugi05.bsky.social · 22/10/2025
New paper from the lab! Many animal cells exhibit chiral cell surface dynamics, which are proposed to drive left–right asymmetric patterning. However, the molecular mechanisms linking these events remain unclear. authors.elsevier.com/a/1l%7E7B3QW...
authors.elsevier.com
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