Reposted by Kenji SugiokaSue Biggins @suebiggins.bsky.social · 18/08/2026Junior faculty position in Basic Sciences @fredhutch.org! Please repost! 38097
Reposted by Kenji SugiokaAlex Eve @amjeve.uk · 26/07/2026Chirality (handedness) is found across life. Nematode worms form chirality early, as cells divide in a spiral pattern. @sugi05.bsky.social shows how cells roll using intercellular scaffolds, axis tilts and cell-substrate adhesion via finger-like filopodia to direct clockwise cell division. #2026SDB 201
Reposted by Kenji SugiokaHItoshi Sawa @uncnondpy.bsky.social · 28/05/2026Worm folks, mark your calendar for International worm meeting in Kobe Japan, July 18-22, 2027. 011
Kenji Sugioka @sugi05.bsky.social · 26/05/2026Tagging the UBC link: ubc.wd10.myworkdayjobs.com/en-US/ubcfac...ubc.wd10.myworkdayjobs.comPostdoctoral Research FellowAcademic Job Category Faculty Non Bargaining Job Title Postdoctoral Research Fellow Department Research | Sugioka | Department of Zoology (Kenji Sugioka) Posting End Date June 18, 2026 Note: Applicati... 010
Kenji Sugioka @sugi05.bsky.social · 26/05/2026One month left to apply for this postdoc position in my lab at UBC! Funding is available for up to five years #DevBio #cellbio 21113
Reposted by Kenji SugiokaMélanie Laurin @melanielaurin.bsky.social · 22/05/2026SAVE THE DATE for the 13th Canadian Developmental Biology Conference — March 7–10, 2027 — bringing together researchers, trainees, and innovators in developmental biology from across Canada and beyond. 01723
Kenji Sugioka @sugi05.bsky.social · 15/05/2026(the paper also shows that I’m still not useless at the bench.) I was tasked the last experiment which was inspired by Yukinobu Arata-san’s work (Development 2010) from the Sawa lab @uncnondpy.bsky.social 010
Kenji Sugioka @sugi05.bsky.social · 15/05/2026Very insightful work from the Goehring lab on the control of cell polarity tunability during development! Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues | Science Advances www.science.org/doi/10.1126/...science.orgCell cycle oscillations in a polarity network facilitate state switching by morphogenetic cuesRegulation of PAR network feedback by CDK-1 dynamically optimizes a sensitivity-stability trade-off during development. 020
Kenji Sugioka @sugi05.bsky.social · 21/11/2025Just got what felt like my first generative AI reviewer at one of respected Cell Bio journals. Declined to revise (lost interest in this journal) and submitted to Genetics right away 020
Kenji Sugioka @sugi05.bsky.social · 22/10/2025Adding another link. www.cell.com/current-biol... #Devbiocell.comCadherin flow translates cortical chirality into left-right asymmetric cell division dynamics in Caenorhabditis elegans embryosKhor et al. show that cadherin, a major adhesion molecule in animals, undergoes sequential polarized flows in Caenorhabditis elegans embryos. These flows establish a chiral cell-cell adhesion pattern ... 010
Kenji Sugioka @sugi05.bsky.social · 22/10/2025The work was spearheaded by MSc student Mi Jing Khor, with support from PhD candidate Yuxuan Rain Xiong and undergrad Gagan Sangha. 100
Kenji Sugioka @sugi05.bsky.social · 22/10/2025The established chiral cadherin patch interacts asymmetrically with the contractile ring, likely driving its rightward closure, the first detectable left–right asymmetry in C. elegans. 100
Kenji Sugioka @sugi05.bsky.social · 22/10/2025We showed that both ventral and left–right asymmetric cadherin flows are required to generate a chiral cadherin patch pattern. 100
Kenji Sugioka @sugi05.bsky.social · 22/10/2025We found that cadherin at cell–cell contacts exhibits two distinct flows, such as ventral flow and left–right asymmetric flow, each driven by ECM and RhoA signaling (left movie). The resulting cadherin patch pattern is chiral, meaning it cannot be superimposed on its mirror image 110
Kenji Sugioka @sugi05.bsky.social · 22/10/2025We used the 2nd mitosis of C. elegans as a model system, which shows both chiral cortical dynamics and L-R asymmetric closure of the contractile ring. Our past study shows that cell adhesion drives asymmetric ring closure in this cell type. www.nature.com/articles/s41...nature.comContractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis - Nature CommunicationsContractile ring formation, positioning, and closure is influenced by tissue mechanics, though how this information is transmitted is unclear. Here they show that Anillin is critical for a mechanosens... 130
Kenji Sugioka @sugi05.bsky.social · 22/10/2025New paper from the lab! Many animal cells exhibit chiral cell surface dynamics, which are proposed to drive left–right asymmetric patterning. However, the molecular mechanisms linking these events remain unclear. authors.elsevier.com/a/1l%7E7B3QW...authors.elsevier.com 172