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Stephanie Orchanian

@stephorch.bsky.social
26 followers 47 following 2 posts

UCLA Chancellor’s Postdoctoral Fellow studying the maternal gut microbiome

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Reposted by Stephanie Orchanian
Elaine Hsiao @pipethero.bsky.social · 15/05/2026
📣 Our lab is recruiting postdocs to lead new fully funded projects on mechanisms of microbiome–gut–brain signaling & microbial regulation of brain–body interactions in disease, w supportive clinical collaborators. Expertise in gut–brain, systems neuro, or neuroimmunology preferred. Please email 📧
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Reposted by Stephanie Orchanian
Elaine Hsiao @pipethero.bsky.social · 25/11/2025
Excited to share new work by Guli Agirman + co that identifies a direct mechanism linking gut microbial imidazole propionate to stress! 🧠🦠 Btw this image was made by Nano Banana Pro 🍌. First time I've gotten a model to accurately generate a science graphic 🤯 authors.elsevier.com/a/1mA5M6t8JE...
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Stephanie Orchanian @stephorch.bsky.social · 10/07/2025
Excited to share our recent publication in this month's issue of mBio, based on my PhD research. We show that replication of 𝘛. 𝘨𝘰𝘯𝘥𝘪𝘪 is required to trigger a localized immune response in the brain! 🧠 bit.ly/3TA9ALj
bit.ly
Toxoplasma gondii parasites induce a localized myeloid cell immune response surrounding parasites in the brain during acute infection | mBio
Toxoplasma gondii is a brain-infecting parasite, and the mobilization of peripheral immune cells to the brain is critical for controlling T. gondii infection. However, the initial events driving these...
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Reposted by Stephanie Orchanian
Elaine Hsiao @pipethero.bsky.social · 02/05/2025
Thrilled to share this collaborative work by Kristie Yu, Francis Chandra, Amina Schartup and teams @Scripps_Ocean and @UCLA showing that an engineered gut bacterium can be used to reduce the neurotoxic effects of dietary methylmercury www.cell.com/cell-host-mi...
cell.com
An engineered gut bacterium protects against dietary methylmercury exposure in pregnant mice
Yu and Chandra et al. engineered a commensal gut microbe, Bacteroides thetaiotaomicron, to detoxify methylmercury (MeHg). The engineered bacterium reduces MeHg in the intestinal lumen, limits its accu...
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Reposted by Stephanie Orchanian
Journal of Clinical Investigation @jci.org · 20/02/2025
Maternal microbiome is a cornerstone of maternal and fetal health. buff.ly/431YoNu @stephorch.bsky.social‬ & @pipethero.bsky.social highlight gut microbiome x environmental interactions at the maternal-fetal interface that influence the brains of pregnant people and developing offspring.
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Stephanie Orchanian @stephorch.bsky.social · 17/02/2025
Curious about how the gut microbiome modulates the neurological health of pregnant women and their offspring? Check out my recent review with @pipethero.bsky.social out now @jclinical-invest.bsky.social! 🦠🤰👶🧠 www.jci.org/articles/vie...
jci.org
JCI - The microbiome as a modulator of neurological health across the maternal-offspring interface
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