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Steph Herrlinger

@stephherrlinger.bsky.social
39 followers 53 following 4 posts

Neuroscience postdoc studying cognitive dysfunction in neuropsychiatric disorders | #DSPANScholar #ARCSScholar

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Reposted by Steph Herrlinger
Biological Psychiatry @biologicalpsych.bsky.social · 08/03/2026
This review examines the GluN2D subunit of NMDA receptors, detailing its developmentally regulated, cell-type specific expression in interneurons, its role in excitatory-inhibitory balance, and its growing significance in neuropsychiatric and neurological disorders.
biologicalpsychiatryjournal.com
GluN2D NMDARs: Bridging Physiology and Pathology
NMDA receptors are pivotal mediators of excitatory neurotransmission and play crucial roles in normal brain development, synaptic plasticity, and higher-order cognitive functions such as learning and…
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Reposted by Steph Herrlinger
Nature Portfolio @natureportfolio.nature.com · 28/02/2026
Aged adults with extraordinary memory capacity – known as SuperAgers – exhibit a unique neurogenesis profile with a surprisingly high number of young neurons, according to a study published in Nature. 🧪 #Neuroscience
go.nature.com
Human hippocampal neurogenesis in adulthood, ageing and Alzheimer’s disease - Nature
Mapping of neurogenesis in human hippocampi across ages and different cognitive abilities using multiomic single-cell sequencing reveals distinct signatures between cognitive preservation and decline.
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Steph Herrlinger @stephherrlinger.bsky.social · 24/02/2026
Trying to get at some biomarkers: white blood cells maybe? www.sciencedirect.com/science/arti...
sciencedirect.com
White Blood Cell Proportions Are Associated With Response to Psychosocial Therapy in Young People at Ultra-High Risk for Psychosis
White blood cell (WBC) counts, DNA methylation, and gene expression are reported to be associated with psychosis. However, it is not known whether the…
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Reposted by Steph Herrlinger
Biological Psychiatry @biologicalpsych.bsky.social · 07/02/2026
Increased reactive astrocyte activity in the medial orbitofrontal cortex underlies cognitive impairments in schizophrenia.
biologicalpsychiatrycnni.org
Reactive astrocytes and network functional connectivity underlying cognitive symptoms in schizophrenia: a PET and fMRI study
Cognitive symptoms are among the core features of schizophrenia, but their underlying mechanisms remain unclear. Current hypotheses suggest that alterations in the frontal cortex cause network…
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Steph Herrlinger @stephherrlinger.bsky.social · 24/02/2026
Like we’ve been seeing for some time now
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Steph Herrlinger @stephherrlinger.bsky.social · 24/02/2026
So cool 😃 Translational level differences at cell type resolution in CA3/CA1 ♥️
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Reposted by Steph Herrlinger
Khashoggi's Ghost @urocklive1.bsky.social · 13/03/2025
A new study revealed the presence of microplastics – tiny fragments of degraded plastic – in human brain tissue. While previous research has identified microplastics in the liver, kidneys, and placenta, this suggests that the brain may be especially vulnerable to these tiny synthetic particles.
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