Reposted by Steph Herrlinger
This review examines the GluN2D subunit of NMDA receptors, detailing its developmentally regulated, cell-type specific expression in interneurons, its role in excitatory-inhibitory balance, and its growing significance in neuropsychiatric and neurological disorders.
biologicalpsychiatryjournal.com
GluN2D NMDARs: Bridging Physiology and Pathology
NMDA receptors are pivotal mediators of excitatory neurotransmission and play crucial roles in normal brain development, synaptic plasticity, and higher-order cognitive functions such as learning and…