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Stephen Lapinsky

@stephenlap.bsky.social
908 followers 265 following 66 posts

Critical Care Obstetric Medicine Pulmonary & Critical Care in pregnancy Sinai Health System & University of Toronto 🇨🇦🇿🇦

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Stephen Lapinsky @stephenlap.bsky.social · 26/04/2025
Mechanism of preeclampsia: fascinating talk @nasom-obmed.bsky.social 2025 by Dr. Surendra Sharma on the role of impaired autophagy related to tau protein aggregation, and treatable with trehalose pubmed.ncbi.nlm.nih.gov/38760513/
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Stephen Lapinsky @stephenlap.bsky.social · 26/04/2025
Top 5 articles in OB Medicine in 2024 presented at @nasom-obmed.bsky.social 2025 meeting
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Stephen Lapinsky @stephenlap.bsky.social · 25/04/2025
Jayson Potts opening the @nasom-obmed.bsky.social 2025 meeting in Newport, RI
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Stephen Lapinsky @stephenlap.bsky.social · 04/04/2025
New review on PlGF & sFlt1 in Obstetic care, by @sinaihealth.bsky.social leaders in the field. journals.sagepub.com/doi/10.1177/...
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Stephen Lapinsky @stephenlap.bsky.social · 17/03/2025
Time to register for NASOM 2025 April 25-26, Newport, Rhode Island Or participate virtually! Early bird rate ends March 31st nasom.org/current-year...
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Stephen Lapinsky @stephenlap.bsky.social · 24/02/2025
Cystic fibrosis & pregnancy New data from American Cystic Fibrosis Foundation Patient Registry. Pregnancy assoc with: - reduced hazard of death compared to never-pregnant - no significant impact on lung function. www.sciencedirect.com/science/arti...
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Stephen Lapinsky @stephenlap.bsky.social · 13/02/2025
I never really thought much about where our fruit came from, but now that we buy non-American, these Italian & Israeli options are great! 🇨🇦
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Stephen Lapinsky @stephenlap.bsky.social · 25/01/2025
External aortic compression in OB hemorrhage by Alvaro Nieto-Calvache. A simple maneuver to control bleeding and buy time www.ajog.org/article/S000... And video: www.ajog.org/cms/10.1016/...
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Stephen Lapinsky @stephenlap.bsky.social · 17/01/2025
Early warning scores in maternal sepsis Detailed evaluation of several EWS in a large WHO database of OB sepsis: - OB & sepsis specific scores performed better - none accurate enough for clinical use - incomplete data is a problem www.thelancet.com/journals/ecl...
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Stephen Lapinsky @stephenlap.bsky.social · 14/01/2025
Valuable new paper - rare but very difficult when you see it: “Position statement on the diagnosis and management of acute leukaemia and aggressive lymphomas in pregnancy” by an 🇦🇺 group including @slobsmedsyd.bsky.social www.thelancet.com/journals/lan...
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Stephen Lapinsky @stephenlap.bsky.social · 18/12/2024
OB Medicine Conference abstracts now online in the journal 𝘖𝘣𝘴𝘵𝘦𝘵𝘳𝘪𝘤 𝘔𝘦𝘥𝘪𝘤𝘪𝘯𝘦 (open access)! MOMS 2024 (UK meeting): journals.sagepub.com/doi/abs/10.1... ISOM/SOMANZ 2024: journals.sagepub.com/doi/full/10....
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Stephen Lapinsky @stephenlap.bsky.social · 10/12/2024
My first (1995?)
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Stephen Lapinsky @stephenlap.bsky.social · 07/12/2024
Toronto traffic sunrise
Highway traffic with the CN tower and orange sky in the background
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Stephen Lapinsky @stephenlap.bsky.social · 01/12/2024
OK, I had to do one also (outside at 0 C)…
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Stephen Lapinsky @stephenlap.bsky.social · 26/11/2024
Is this respiratory acidosis the same? Limited data! The acidosis may: - right shift the fetal Hgb O₂ dissociation curve - may adversely affect maternal & fetal hemodynamics
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Stephen Lapinsky @stephenlap.bsky.social · 24/11/2024
Animal studies are not conclusive, and also not applicable to the human situation, given the marked anatomical and physiological differences between human and animal placentas
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Stephen Lapinsky @stephenlap.bsky.social · 24/11/2024
Also, excess supplemental oxygen may reduce cardiac output (by increasing peripheral resistance) and result in a net decrease in oxygen delivery
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Stephen Lapinsky @stephenlap.bsky.social · 24/11/2024
The fetus manages with very low PaO₂ levels as the fetal hemoglobin is left-shifted
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Stephen Lapinsky @stephenlap.bsky.social · 24/11/2024
Oxygen delivery to the fetus depends on (as for any organ): - oxygen saturation - hemoglobin - blood flow SaO₂ has the narrowest range of variation, much bigger changes occur in blood flow. Blood flow likely much more important than small changes in SaO₂
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Stephen Lapinsky @stephenlap.bsky.social · 24/11/2024
We often read and hear that oxygen saturation needs to be kept higher than the non-pregnant patient - is this true?
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Stephen Lapinsky @stephenlap.bsky.social · 17/11/2024
Carolyn Calfee on subtypes/phenotypes in sepsis
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Stephen Lapinsky @stephenlap.bsky.social · 17/11/2024
Critical Care Canada Forum 2024 (criticalcarecanada.com) Fellows Day - currently Sepsis session, Manu Shankar-Hari speaking, to be followed by Carolyn Calfee
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Stephen Lapinsky @stephenlap.bsky.social · 13/11/2024
Valuable messages from the 2024 MBRRACE report on maternal deaths in UK. - causes of maternal mortality: PE, COVID, cardiac, mental health - inequality plays a major role - role for a national risk assessment tool
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Stephen Lapinsky @stephenlap.bsky.social · 09/11/2024
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