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Jason Stein

@steinlab.bsky.social
559 followers 315 following 11 posts

Associate to the professor, UNC Chapel Hill Dept of Genetics and UNC Neuroscience Center, studying genetic effects on brains, steinlab.org

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Reposted by Jason Stein
Hyejung Won @hyejungwon.bsky.social · 23/09/2026
1/ I’m excited to share our new work, now out in @natneuro.nature.com! This was a wonderful collaboration with my long-term collaborator @steinlab.bsky.social, led by two fantastic trainees, @nanamatoba.bsky.social and Jessica McAfee. www.nature.com/articles/s41...
nature.com
Massively parallel assessment of gene regulatory activity at human cortical-structure-associated variants - Nature Neuroscience
A large-scale functional screen identified noncoding variants that regulate gene activity during human brain development, providing insights into the molecular mechanisms that shape differences in hum...
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Jason Stein @steinlab.bsky.social · 28/07/2026
Come be our colleague at UNC! The Department of Cell Biology & Physiology and the Neuroscience Center at the University of North Carolina at Chapel Hill invite applications for an open-rank, tenure-track faculty position. Please apply here: unc.peopleadmin.com/postings/322...
unc.peopleadmin.com
Open Rank
The Department of Cell Biology & Physiology and the Neuroscience Center at the University of North Carolina at Chapel Hill invite applications for an open-rank, tenure-track faculty position. The succ...
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Reposted by Jason Stein
Ian Curtin @iancur.bsky.social · 11/03/2026
Why are brains with Chd8 mutations larger? 🧠 It’s a top risk factor for autism, but the “how” and “when” of this growth have been unknown. Our new study in @bioRxiv images 118 brains in a large-scale 3D pipeline to help solve the mystery! 🔍 tinyurl.com/y4fm6km6 Thread 1/10
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Reposted by Jason Stein
Greg Copenhaver @copenhaverlab.bsky.social · 08/01/2026
Exciting neuroscience and bioelectronics engineering by Wubin Bai and @steinlab.bsky.social working with #UNC Institute for Convergent Science. Their technology may open new doors for psychiatric and neuro treatments. innovate.unc.edu/cracking-the...
innovate.unc.edu
Cracking the Brain’s Code: New Sensor Wraps the Human Mind in 3D Insight | Innovate Carolina
Peek inside a laboratory at the UNC Neuroscience Center and you might spot what looks like a collection of tiny white beads spinning in a container of red-tinted liquid. No larger than small peas or p...
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Jason Stein @steinlab.bsky.social · 27/10/2025
Excited to share our new preprint on molecular gene x treatment interactions led by Jordan Valone, Brandon Le, and @nanamatoba.bsky.social. www.medrxiv.org/content/10.1.... Here, we tried to further develop the "pharmacogenomics in a dish" approach for psychiatry.
medrxiv.org
Assessing molecular gene by treatment interactions using a population of neural progenitors exposed to valproic acid and lithium
Gene by treatment (GxT) interactions likely contribute to variability in clinical response, but are difficult to identify in population studies. Here, we applied psychiatric and neurological disorder ...
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