Excited to share that our collaborative work on PLpro inhibitors is published! Using a model that replicates symptoms seen in long COVID patients, we show that a potent antiviral can prevent long-term disease. A big step forward in long COVID therapy. #LongCOVID #PLpro #COVID19 #SARSCoV2 #Antivirals
nature.com
A novel PLpro inhibitor improves outcomes in a pre-clinical model of long COVID - Nature Communications
A novel antiviral targeting the SARS-CoV-2 PLpro protease shows strong efficacy in a mouse model, preventing lung pathology and reducing brain dysfunction. The study provides proof-of-principle that P...
