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Stavroula Tsaridou

@stavroulatsar.bsky.social
39 followers 53 following 0 posts

PhD student of the Medical Oncology Department of @UMCG studying DNA damage responses. 🧬🔬

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Reposted by Stavroula Tsaridou
Alex Carver @alexcarver.bsky.social · 05/12/2024
NEW in @science.org, so happy to contribute to our understanding of the molecular machine, Fidgetin-like 1 (FIGNL1), and elucidating the mechanism of why cells cannot survive when it is lost! #ScienceResearch science.org/doi/10.1126/... (1/7)
science.org
Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin
Maintaining genome integrity is an essential and challenging process. RAD51 recombinase, the central player of several crucial processes in repairing DNA and protecting genome integrity, forms filamen...
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Reposted by Stavroula Tsaridou
Drew Berry wehi.tv @drewberry.bsky.social · 04/12/2024
Delighted to publish my new molecular animation: DNA Break Repair by Homologous Recombination youtu.be/Xe-83tBcxhs
youtu.be
DNA Break Repair by Homologous Recombination (2024) Drew Berry wehi.tv
YouTube video by WEHImovies
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Reposted by Stavroula Tsaridou
marcelvanvugt.bsky.social @marcelvanvugt.bsky.social · 30/11/2024
Happy to share our study by Francien Talens and many colleagues on RAD51 foci formation as a functional marker for PARPi sensitivity in ovarian cancer PDX models. academic.oup.com/narcancer/ar...
academic.oup.com
RAD51 recruitment but not replication fork stability associates with PARP inhibitor response in ovarian cancer patient-derived xenograft models
Abstract. Poly(ADP‐ribose) polymerase (PARP) inhibitors (PARPis) are currently used to treat BRCA1/2 mutant cancers. Although PARPi sensitivity has been at
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