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Siddhartha Mitra

@ssmitra.bsky.social
810 followers 496 following 7 posts

Macrophage aficionade | My lab studies CNS #immune cells in Adult and pediatric malignant #braintumors. We research novel #immunotherapy modalities to treat childhood #tumors | Lover of Historical Roman Military Fiction | Perpetual annoyance to my children

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Siddhartha Mitra @ssmitra.bsky.social · 06/09/2025
Excited to announce our latest manuscript! burning question: do macrophages feel the same after “eating” a tumor cell as we do after a bean burrito vs. a kale salad? macrophages are reprogrammed by what they ingest. jitc.bmj.com/content/13/9...
jitc.bmj.com
Differential phagocytosis induces diverse macrophage activation states in malignant gliomas
Background Diffuse midline glioma (DMG) and glioblastoma (GBM) are aggressive brain tumors with limited treatment options. Macrophage phagocytosis is a complex, tightly regulated process governed by c...
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Siddhartha Mitra @ssmitra.bsky.social · 08/03/2025
Finally a Mitra/Hankinson lab outing. Fully rebuilt after COVID. Celebrating birthdays and just each other
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Siddhartha Mitra @ssmitra.bsky.social · 27/01/2025
An absolutely phenomenal paper: Cancer cells can poison attacking immune cells by filling them with defective mitochondria ― dampening the body’s defensive forces and helping the tumour to evade eradication www.nature.com/articles/s41...
nature.com
Immune evasion through mitochondrial transfer in the tumour microenvironment - Nature
Mitochondria with mutations in their DNA from cancer cells can be transferred to T cells in the tumour microenvironment, which leads to T cell dysfunction and impaired antitumour immunity.
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Siddhartha Mitra @ssmitra.bsky.social · 23/11/2024
Awesome meeting up with former lab member Sharareh Gholamin and Johana Theruvath at #SNO2024
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Siddhartha Mitra @ssmitra.bsky.social · 22/11/2024
Phenomenal talk by Doug Hanahan on the intersection of cancer neuroscience and Immunology #SNO2024
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Reposted by Siddhartha Mitra
Oded Rechavi @odedrechavi.bsky.social · 19/11/2024
Hope I'm the first to post this all time classic on this platform
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Reposted by Siddhartha Mitra
Nicole Rust @nicolecrust.bsky.social · 17/11/2024
Terrific piece summarizing a recent report: Every dollar of NIH research funding doubles in economic returns www.fiercebiotech.com/research/rep...
fiercebiotech.com
Report: Every dollar of NIH research funding doubles in economic returns
Research funded by the National Institutes of Health (NIH) generated $2.46 in economic activity for every $1 of funding in 2023, a total of $92.9 billion, according to an
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