Shamphavi Sivabalasarma @sshamphavi.bsky.social · 27/04/2026We wondered what drove the variability in the systems. Using structure-guided phylogenetics, we saw that structural expansion of core components drove the diversification of the archaeal TFF superfamily! (3/n) 100
Shamphavi Sivabalasarma @sshamphavi.bsky.social · 27/04/2026We find that archaea encode a striking diversity of TFF systems, up to 12 distinct systems per genome, exceeding the diversity typically observed in bacteria. 151