The mitochondrial–peroxisomal fission adaptor MFF is identified as a selective pro-ferroptotic mediator, and the newly developed MFF–SPARK sensor enables high-content screening of ferroptosis-sensitizing compounds and the discovery of upstream regulators of MFF.

Nature - Mechanisms of Transcriptional Regulation by Salicylic Acid Receptors

High temperatures make cell membranes weak and leaky. Rice plants rapidly counteract this effect by adjusting membrane lipid content, enabling them to resist heatwaves.

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Chloroplast plastoglobules act as nitrogen-assimilation hubs in maize, with key enzymes enhancing nitrogen-use efficiency and offering new strategies for developing high-yield, sustainable crops.

A small-peptide signalling axis involving RGF family members controls resilience to cold stress in tomatoes and rice; modulating this pathway prevents cold-induced yield losses.

ATG8 conjugation on damaged lysosomes triggers rapid assembly of a protein complex containing TFG, which directs lysosomal membrane repair by recruiting ESCRT proteins to sites of damage.

Teosinte alleles enhance nitrogen assimilation and seed protein without lowering crop yield when expressed in modern maize, providing a powerful strategy for crop improvement to meet future population demands.

Plants sense water deficiency through SAM8 protein condensation, which responds to reduced hydration and triggers stress adaptation by altering RNA export and gene translation.

A fungal long non-coding RNA from Magnaporthe oryzae translocates into rice cells to sequester a host microRNA that normally represses PKR1, a negative immunity regulator, thereby facilitating infection and revealing a widespread RNA-based pathogen–host interaction mechanism.

Nature - Ubiquitination of glycogen and metabolites in cells and tissues

Experiments in Arabidopsis demonstrate that group VII ethylene response factors show differential responses to different stimuli, enabling plants in flood-prone environments to adapt to both submergence-induced hypoxia and reoxygenation upon desubmergence.

SnRK1β1A in rice promotes susceptibility to multiple fungal diseases, and disrupting this infection-inducible gene confers broad-spectrum resistance without compromising growth or yield under normal f...

SUMM2, a coiled-coil NLR, promotes the assembly of higher-order resistosome clusters to initiate cell death in plants.

The E3 ubiquitin ligase NLA postively regulates cold tolerance and negatively regulates phosphate uptake in maize, and a genetically engineered variant of this enzyme leads to improved cold ...

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Cells can sense mitochondrial damage through signalling via an unimported mitochondrial targeting sequence.

Soil compaction traps ethylene around roots, which causes transcriptional upregulation of Auxin Response Factor1, resulting in decreased root cortical cell wall thickness and thereby promoting root ra...

An investigation of plant receptor-like kinases identifies regions of these proteins that control whether immune or symbiotic signalling pathways are activated, with minimal changes to specific r...

A single-cell multi-omics atlas of rice is revealed, providing insight into cell-type functions and molecular programs.

The integration of omics technologies, genome editing and protein design with artificial intelligence (AI) promises rapid advances in the field of crop improvement that will improve global food securi...

Cleavage by pathogen-derived proteases of an engineered chimeric protein activates its plant immune receptor component, enabling broad-spectrum resistance to pathogens in plants.

The salicylic acid (SA) biosynthesis pathway—involving ligation of benzoyl coenzyme A and benzyl alcohol to give benzyl benzoate; hydroxylation of benzyl benzoate to give benzyl salicylate; and cleava...

The periderm layers of plants form an outer protective barrier. If the periderm is broken, movement of the gases ethylene and oxygen triggers a healing process.

From today, all new submissions to Nature that are published will be accompanied by referees’ reports and author responses — to illuminate the process of producing rigorous science.

Targeting a non-natural micropeptide ‘killswitch’ to several biomolecular condensates altered condensate compositions and revealed condensate functions in human cells

A study presents EndoMAP.v1, a resource that combines information on protein interactions and crosslink-supported structural predictions to map the interaction landscape of early endosomes.

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Science stands to benefit from a project in which experienced academics and early-career researchers co-review studies.

Nature - A kinase mediator of rhizobial symbiosis and immunity in Medicago

Nature - Molecular basis of SIFI activity in the integrated stress response

Single-cell RNA sequencing and spatial transcriptomic approaches reveal major expression changes in outer root cell types when grown in soil versus gel conditions, and also uncover how root tissu...

The LPD-3 complex structure reveals protein–lipid interactions that suggest a model for how the native LPD-3 complex mediates bulk lipid transport and provides a foundation for mechanistic studies of ...

Spontaneous parthenogenesis in sunflower has been used to develop a scalable doubled haploid breeding system.

High spatiotemporal precision tracking using 3D MINFLUX shows that nuclear import and export occur in overlapping regions of the central pore, providing insight into transport across the nuclear pore ...

Viral coat proteins are perceived by the RING1–IBR–RING2-type ubiquitin ligase, initiating the first step of the natural antiviral response in rice.

cAMP produced by the TIR1/AFB receptors of the main endogenous developmental plant hormone auxin acts as a true second messenger, revising the established paradigm of transcriptional auxin signalling.

We find that, in mice, although the individual loss of Parkin or OMA1 does not affect mitochondrial integrity, their combined loss results in small body size, low locomotor activity, premature death, ...

In Arabidopsis, mechanisms for NRG1A activation by recognition of a modified host EDS1–SAG101 complex, and NRG1A inhibition by NRG1C through sequestration of activated EDS1–SAG101, show activation and...

Nuclear calcium oscillations initiate plant–arbuscular mycorrhiza and nitrogen-fixing bacteria symbioses for nutrient acquisition, with a newly discovered autoactive CNGC15 mutant enhancing ...

SCF–FBXO31 scans proteins for C-terminal amidation and marks them for subsequent proteasomal degradation.

Precise regulation of the phytohormone gibberellin to optimal levels may not only confer alkali–thermal tolerance to Green Revolution rice varieties but may also further enhance their yield, and ...

This study demonstrates that cryo nanoscale secondary ion mass spectrometry (CryoNanoSIMS) enables direct multi-elemental imaging at subcellular resolution of macro- and micronutrients or trace elemen...