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Reposted by SOURJYA MAL

van Gemmeren Lab @vangemmerenlab.bsky.social · 13/04/2026

Check out this excellent review by @sourjyamal.bsky.social on carboxylic acid directed C(sp³)–H functionalization, covering distinct mechanistic strategies (C–H activation, HAT, etc), catalyst design principles, and their applications in building complex molecules. doi.org/10.1021/acs....

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Reposted by SOURJYA MAL

van Gemmeren Lab @vangemmerenlab.bsky.social · 03/04/2026

Another major milestone has been achieved! Sourjya Mal presented an outstanding defense and has now well-deservedly earned the title of Dr. Mal!!!🎓 Congratulations from the van Gemmeren group, and all the best for your future journey!

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van Gemmeren Lab @vangemmerenlab.bsky.social · 09/02/2026

Just one ''click'' away! Dive into our newest publication showcasing non-directed C-H olefination as a powerful tool to access versatile linchpins for bioconjugation and/or ABPP studies! doi.org/10.1002/chem.202600018 Congratulations to Tommaso Braga and @mariahergert.bsky.social !

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van Gemmeren Lab @vangemmerenlab.bsky.social · 02/12/2025

A direct synthesis of versatile active esters! Massive congratulations to Simon Kaltenberger, Joshua Meinshausen, @jyotirmoydey.bsky.social and Celia Sanchez-Gonzalez on the development of a widely applicable sterically controlled alkoxycarbonylation of arenes now in JACS Au doi.org/10.1021/jacs...

A reaction scheme showing the direct alkoxycarbonylation of arenes using a dual ligand-based catalyst system.

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van Gemmeren Lab @vangemmerenlab.bsky.social · 23/10/2025

Exttemely proud of this computational and experimental mechanistic work headed by @chimicafritz.bsky.social and supported by @monikaravi.bsky.social just out in @angewandtechemie.bsky.social doi.org/10.1002/anie... #chemsky

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van Gemmeren Lab @vangemmerenlab.bsky.social · 15/09/2025

Access SEAr-type products in typically disfavored positions! Contratulatons to Rita, @jyotirmoydey.bsky.social and Elisa showin in Org. Lett. how nondirected C-H activation and oxidative cleavage can be used to obtain challenging regioisomers in formylation and carboxylation doi.org/10.1021/acs....

A reaction scheme showing a generic arene structure, which is first olefinated through a nondirected C-H olefination, followed by two oxidative cleavage pathways, one giving carboxylation products the other giving formylation products.

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Synlett Journal @synlettjournal.bsky.social · 21/08/2025

A simple, scalable method by Jurk & van Gemmeren @vangemmerenlab.bsky.social to convert secondary sulfonamides into sulfonyl fluorides using affordable #DAST ⚗️, yielding excellent results! These sulfonyl fluorides readily couple with amines to create diverse libraries. #SuFEx 👉 buff.ly/hjkyEap

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van Gemmeren Lab @vangemmerenlab.bsky.social · 13/07/2025

Congratulations to aol three @uni-kiel.de candidates who were selected to participate in the Lindau Nobel Laureate meeting. In particular of course our very own @sourjyamal.bsky.social. A well deserved recognition of his excellent doctoral studies. #proudPI #chemsky www.uni-kiel.de/de/detailans...

uni-kiel.de

Drei Nachwuchsforschende der Uni Kiel bei Nobelpreisträger-Tagungen

Die Einladungen sind auch eine Auszeichnung für die Chemie und die Wirtschaftswissenschaften an der CAU.

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van Gemmeren Lab @vangemmerenlab.bsky.social · 04/07/2025

Great job Edis and @sourjyamal.bsky.social! Their work on the synthesis of γ-Alkylidene Lactones has just been accepted for publication in the @rsc.org journal @chemicalscience.rsc.org doi.org/10.1039/D5SC...

Table of contents graphic showing the reaction of an aliphatic carboxylic acid with a styrene to give a γ-vinylidene lactone via tripple C-H functionalization. The structure of the ligand used is given as well as bullet points showing the main strenghts of the report, such as a broad substrate scope.

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van Gemmeren Lab @vangemmerenlab.bsky.social · 29/06/2025

Just saw on the OL homepage that the article currently leads the journals most read list, thanks for all the interest in our work! pubs.acs.org/action/showM...

pubs.acs.org

Organic Letters :

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SOURJYA MAL @sourjyamal.bsky.social · 12/06/2025

Check out our newest C(sp³)–O bond formation strategy: doi.org/10.1021/acs....

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van Gemmeren Lab @vangemmerenlab.bsky.social · 11/04/2025

Congratulations to Edis and @sourjyamal.bsky.social, who have completed their studies on a new and efficient approach towards gamma-alkylidene lactones directly from carboxylic acids and lactones now posted on @chemrxiv.bsky.social chemrxiv.org/engage/chemr... #chemsky #chemistry

Graphical abstract of a manuscript detailing the reaction between a carboxylic acid and a styrene under palladium catalysis.

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van Gemmeren Lab @vangemmerenlab.bsky.social · 04/02/2025

Thanks for all the interest in the study. It is now amongst the currently most read in ACS Catalysis

A screebshot from the ACS Catalysis homepage shiwing the article in the most read list.

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SOURJYA MAL @sourjyamal.bsky.social · 31/01/2025

Smashing distal C–H bonds of the unprecedented β-non-quaternary acids has been a formidable task over the years; several years of our involvement in 'Ligand Design' finally broke the deadlock! Thanks to @vangemmerenlab.bsky.social for guiding us to achieve this feat !

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van Gemmeren Lab @vangemmerenlab.bsky.social · 19/07/2024

We have developed a direct gamma-lactonization of carboxylic acids. The scope includes beta-non-quaternary subatrates that were until now out of reach for carboxylic acid gamma-C-H activation. Congratulations to Tianxiao and Sourjya. Have a look at the study now posted on ChemRXiv t.co/Wu0XtwsEQR

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van Gemmeren Lab @vangemmerenlab.bsky.social · 21/06/2024

Our work on the direct fluorination of carboxylic acids has just appeared in @NatureSynthesis! (www.nature.com/articles/s44...). This terrific study bySourjya Mal, Friedrich Jurk, and Kerstin Hiesinger is highlighted in a press release by our University: www.uni-kiel.de/en/details/n...

nature.com

Pd-catalysed direct β-C(sp3)–H fluorination of aliphatic carboxylic acids - Nature Synthesis

C–F bond formation using transition-metal catalysis is a challenge owing to the high energy barrier associated with reductive elimination. Now the direct β-C(sp3)–H fluorination of aliphatic carboxyli...

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