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Sophia Mädler

@sophia-maedler.bsky.social

PostDoc @mpibiochem.bsky.social in @mannlab.bsky.social | PhD in Biochemistry | Developer of scPortrait & SPARCS | DL-driven representation learning for single-cell image analysis sophia-maedler.com

Posts Replies Media

Reposted by Sophia Mädler

Fabian Theis @fabiantheis.bsky.social · 28/09/2025

🚀 Excited to share scPortrait! Led by Sophia Mädler & Niklas Schmacke w/ the Mann lab — a new @scverse tool for standardized single-cell image data. Enables ML-ready extraction, >1B cell processing, cross-omics, & cancer macrophage insights. 🔗 www.biorxiv.org/content/10.1...

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Sophia Mädler @sophia-maedler.bsky.social · 24/09/2025

So glad to see scportrait finally out on @biorxivpreprint.bsky.social ❤️ Check out the tweetorial about our main findings 👇 It was a pleasure working with everyone who contributed to this project.

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Reposted by Sophia Mädler

Mann Lab @mannlab.bsky.social · 24/09/2025

Our preprint on scPortrait is out! We built a framework + format to turn microscopy into standardized single-cell image datasets. #scPortrait scales >100M cells, integrates with @scverse.bsky.social, & enables cross-modality modeling from morphology to transcriptomics doi.org/10.1101/2025...

doi.org

scPortrait integrates single-cell images into multimodal modeling

Machine learning increasingly uncovers rules of biology directly from data, enabled by large, standardized datasets. Microscopy images provide rich information on cellular architecture and are accessi...

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