iiinova — where your digital self keeps evolving

Sumit Mukherjee @smukherjee89.bsky.social · 11/07/2026

People here may not know this about me, but I am actually a big fan of pop/punk. Anyways, I recently heard a great song that I wanted to recommend to others who might be into this genre of music: share.google/zJznvvHM3b2t...

share.google

honestav & mgk - Crash First (OFFICIAL MUSIC VIDEO)

Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube.

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Tuuli Lappalainen @tuuliel.bsky.social · 10/07/2026

We're recruiting! An open functional genomics postdoc position at @scilifelab-ngi.bsky.social / my lab / Robert Månsson lab. Top notch environment for technology and applications development in lovely Stockholm. Please spread the word or apply if interested: www.kth.se/lediga-jobb/...

kth.se

KTH | Postdoc in genomics

KTH jobs is where you search for jobs at www.kth.se.

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arxiv cs.GT @arxiv-cs-gt.bsky.social · 23/04/2026

Sumit Mukherjee Geometric Comparisons of Electoral Rules Under Feedback arxiv.org/abs/2604.19985

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arXiv cs.GT Computer Science and Game Theory @csgt-bot.bsky.social · 23/04/2026

Sumit Mukherjee: Geometric Comparisons of Electoral Rules Under Feedback arxiv.org/abs/2604.19985 arxiv.org/pdf/2604.19985 arxiv.org/html/2604.19985

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Marvin Sextro @marvinsextro.de · 22/04/2026

[1/6] How can we build virtual cell foundation models that adapt to unseen biological contexts? Meet MapPFN, the first prior-data fitted network (PFN) for perturbation prediction. Meta-learned from a synthetic biological prior, it adapts at inference via in-context learning. 🧵

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Sumit Mukherjee @smukherjee89.bsky.social · 23/04/2026

As you know, I've been simulating electoral systems for a while now (more like a couple months tbh). Well this time I chanced upon something kinda interesting and wrote that up into an arxiv pre-print: arxiv.org/abs/2604.19985 (1/) 🧪💻

arxiv.org

Geometric Comparisons of Electoral Rules Under Feedback

We study how electoral rules shape polarization dynamics when voters and candidates both adapt to repeated election outcomes. We introduce two geometric primitives for comparing rules under this feedb...

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Sumit Mukherjee @smukherjee89.bsky.social · 18/04/2026

Check out my new pre-print. Here we develop an automated approach to value set creating using retrieval + classification, which greatly outperforms zero shot LLM based valie set generation. 🧪

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Sumit Mukherjee @smukherjee89.bsky.social · 15/04/2026

Shubho Noboborsho (Happy Bengali New Year) to all my Bengali friends!!! Hope you all have a wonderful year. :)

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Sumit Mukherjee @smukherjee89.bsky.social · 07/04/2026

Check out my latest notebook on electoral systems: github.com/mukhes3/elec.... This time I ran a pretty ambitious experiment to see how combinations of different factors affect aggregate, majority and minority welfare metrics. (1/)

github.com

electoral_sim/notebooks/majority_vs_minority_welfare.ipynb at main · mukhes3/electoral_sim

An Open Framework for comparing electoral mechanisms across voter distribution scenarios - mukhes3/electoral_sim

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Sumit Mukherjee @smukherjee89.bsky.social · 31/03/2026

A couple more interesting notebooks for those who might be interested: 1. A notebook on one of the most classic and highly cited results in social choice theory (Arrow's impossibility theorem): github.com/mukhes3/elec....

github.com

electoral_sim/notebooks/arrows_impossibility_theorem.ipynb at main · mukhes3/electoral_sim

An Open Framework for comparing electoral mechanisms across voter distribution scenarios - mukhes3/electoral_sim

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Sumit Mukherjee @smukherjee89.bsky.social · 27/03/2026

Did some big updates to the electoral_sim package today (github.com/mukhes3/elec...). The biggest updates are: 1. Added non-sincere voting types 2. Added a notebook comparing FPTP + closed primaries with RCV w/ open primaries under different settings.

github.com

GitHub - mukhes3/electoral_sim: An Open Framework for comparing electoral mechanisms across voter distribution scenarios

An Open Framework for comparing electoral mechanisms across voter distribution scenarios - mukhes3/electoral_sim

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Sumit Mukherjee @smukherjee89.bsky.social · 21/03/2026

Happy Nowruz to all my Iranian friends!!

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Sumit Mukherjee @smukherjee89.bsky.social · 09/03/2026

I wrote my first Medium article (medium.com/@sumitmukher...) about an open source repository I created to simulate different electoral systems under different electoral scenarios. It is not my area of expertise but a topic I have long been interested in. (1/)

medium.com

Electoral-sim: A spatial voting simulator for comparing electoral systems

I am not a social scientist nor have I professionally worked in scientific disciplines adjacent to those that study electoral systems…

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Sumit Mukherjee @smukherjee89.bsky.social · 16/06/2025

My heart goes to out to the ordinary people of Iran and Israel for what seems to me, as an outsider, a completely pointless war. I hope this insanity comes to an end quickly. My hear goes out to the civilians in these countries who really didn't want or deserve this.

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Sumit Mukherjee @smukherjee89.bsky.social · 16/04/2025

Today’s home loss to Arsenal makes it even more obvious.

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Sumit Mukherjee @smukherjee89.bsky.social · 08/04/2025

Ancelotti needs to be fired. Real Madrid have just been uninspiring and at times terrible this season.

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Sumit Mukherjee @smukherjee89.bsky.social · 06/04/2025

As more and more tech companies claim that LLMs will make certain classes of jobs unnecessary in a few years, it amazes me that there is little to no discussion on the effects on the labor force/economy and other societal impacts.

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Sumit Mukherjee @smukherjee89.bsky.social · 04/04/2025

After 3.5 wonderful years at @insitro.bsky.social where I got to work on many interesting problems at the intersection of genetics and ML, I will be joining Oracle Health on Monday as a Senior Applied Science Manager to work on clinical LLMs. (1/)

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Sumit Mukherjee @smukherjee89.bsky.social · 27/03/2025

South Asian friends living in the US - is it me or is Indian food just way more spicy in the US than it is in India (on average)? If y'all agree with me, why do you think this is? Even dishes that were sweet-ish in India, are somehow spicy here.

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Emma Pierson @emmapierson.bsky.social · 18/03/2025

We have a new method, HypotheSAEs, for identifying *interpretable text features that predict a target variable* (aka hypothesis generation). What features of a headline predict engagement? What features of a clinical note predict whether a patient will develop cancer? 1/

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Su-In Lee @suinlee.bsky.social · 11/03/2025

I'm deeply honored to be elected as an ISCB Fellow this year!🏅 Following last year’s ISCB Innovator Award, this recognition strengthens my commitment to advancing computational biology.🧬 Grateful to my students, mentors, and colleagues for their support! www.iscb.org/iscb-news-it...

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Sumit Mukherjee @smukherjee89.bsky.social · 07/03/2025

Imma be honest, I didn't really see a Gavin Newsom and Charlie Kirk colab coming: www.youtube.com/watch?v=9XJ6...? But then again, there are many things about our political climate in 2025 that I didn't see coming. Might be a me thing.

youtube.com

And, This Is Charlie Kirk | This is Gavin Newsom

YouTube video by This is Gavin Newsom

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Sumit Mukherjee @smukherjee89.bsky.social · 03/03/2025

It's shameful that we have billionaires now feeling empowered to go on highly visible podcasts and say Social Security is a 'ponzi scheme' without explaining a clear alternative that doesn't involve kicking seniors to the curb. Truly shameful!

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Sumit Mukherjee @smukherjee89.bsky.social · 14/02/2025

Happy valentine's day to my science fam!! Hope y'all keep doing all the great science!! :)

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Tuuli Lappalainen @tuuliel.bsky.social · 11/02/2025

There's still time to submit an abstract to the legendary Biology of Genomes meeting! Come and present your work alongside the stellar lineup of invited speakers and keynotes. #BOG25

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Sumit Mukherjee @smukherjee89.bsky.social · 11/02/2025

Awesome new paper led by @zmccaw.bsky.social and my amazing colleagues at @insitro.bsky.social !! Great explainer thread below 👇🧪💻🧬

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Mark Cuban @mcuban.bsky.social · 09/02/2025

This is the most relevant article to NIH and research cuts I’ve seen. Imagine if this was today , how many people would be saying “Why are we studying Gila Monsters and their impact on diabetes ? That’s wasted money !” globalnews.ca/news/9793403...

globalnews.ca

How a Canadian scientist and a venomous lizard helped pave the way for Ozempic - National | Globalnews.ca

In 1984, Dr. Daniel Drucker, an endocrinologist from the University of Toronto, discovered a hormone that helped pave the way for popular diabetes drugs such as Ozempic.

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Sumit Mukherjee @smukherjee89.bsky.social · 07/02/2025

I really enjoyed reading this paper. Very interesting and innovative approach to characterize biomarkers and subtypes of MASLD.

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Abdul Muntakim Rafi @muntakimrafi.bsky.social · 27/01/2025

0/ Essential reading for anyone training or using sequence-function models trained on genomic sequences! 🚨 In our new preprint, we explore the ways homology within genomes can cause leakage when training sequence-based models and ways to prevent it

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Nikolai Slavov @slavov-n.bsky.social · 01/02/2025

The success of LLMs has inspired their extension to genomics data. A preprints reports that such models lack understanding of genomics and provide minimal utility, even for basic tasks such as sequence classification. www.biorxiv.org/content/10.1...

biorxiv.org

Genomic Foundationless Models: Pretraining Does Not Promise Performance

The success of Large Language Models has inspired the development of Genomic Foundation Models (GFMs) through similar pretraining techniques. However, the relationship between pretraining performance ...

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Sumit Mukherjee @smukherjee89.bsky.social · 01/02/2025

I was recently trying out this tool from google called NotebookLM that converts PDFs to a podcast format. It's pretty cool. I used it to summarize this paper and found the description pretty accurate: notebooklm.google.com/notebook/7ab.... Check it out. 🧪💻🧬

notebooklm.google.com

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Sumit Mukherjee @smukherjee89.bsky.social · 31/01/2025

Okay, I am back with another thread on multivariate phenotypes. This will be focused on summarizing this paper: www.nature.com/articles/s41.... This paper introduces a SEM based approach to estimate latent factors underlying multiple relevant traits and using them to improve the power of GWASs. (1/)

nature.com

Genomic structural equation modelling provides insights into the multivariate genetic architecture of complex traits - Nature Human Behaviour

Grotzinger et al. develop a multivariate method for analysing the joint genetic architectures of complex traits: genomic structural equation modelling. They provide several applications of the method,...

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Sumit Mukherjee @smukherjee89.bsky.social · 21/01/2025

Okay, what is the point of making 6yo's take standardized tests (talking about iReady) in school and then sending them home with the results. My kid did well and I am proud of him. However, it seems to be making him competitive and I'm not sure how I feel about that.

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Sumit Mukherjee @smukherjee89.bsky.social · 21/01/2025

This new executive action on birthright citizenship is so profoundly sad. While it might be struck down by the courts, I think it tells potential immigrants just how little we think of them. Sad.

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Eric Topol @erictopol.bsky.social · 20/01/2025

Increased amounts of fat in skeletal muscle, a marker of inflammation, is associated with higher risk of major cardiovascular events. From an observational study of >600 participants with PET scans, followed for 6 years (a first) academic.oup.com/eurheartj/ad...

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Sumit Mukherjee @smukherjee89.bsky.social · 10/01/2025

Ok. Folks, I am back from vacation. I am thinking of new topics at the intersection of ML and genetics for my threads. Do people have specific topics or interesting papers that they might want to see explainer threads on? 🧪💻🧬

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Eric Topol @erictopol.bsky.social · 08/01/2025

A new large language of life model (LLLM) for the transcriptome that predicts gene expression within and across human cell types www.nature.com/articles/s41... @nature.com For more on the remarkable surge of LLLMs see erictopol.substack.com/p/learning-t...

nature.com

A foundation model of transcription across human cell types - Nature

A foundation model learns transcriptional regulatory syntax from chromatin accessibility and sequence data across a range of cell types to predict gene expression and transcription factor interactions...

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