Reposted by Sonali J. Bracken, MD, PhDRyan Marino, MD @ryanmarino.bsky.social · 15/03/2025One cool thing about the United States is that there are more people whose job is to deny healthcare coverage without having any medical background than there are people to provide healthcare coverage and they’ve somehow convinced people that the doctors are where the monetary waste is happening 14604170
Sonali J. Bracken, MD, PhD @sjbracken.bsky.social · 14/02/2025It was an honor to present alongside these two esteemed physician-scientists who have pushed the frontiers of transplantation and cell therapy for patients with autoimmune disorders. #Tandem25 www.tandemmeetingsnews.com/experts-trac...tandemmeetingsnews.comExperts trace work to treat autoimmune disorders - Tandem Meetings NewsKeith Sullivan, MD, and others discussed progress with transplantation and cell therapy for autoimmune diseases. 010
Reposted by Sonali J. Bracken, MD, PhDEric Topol @erictopol.bsky.social · 10/01/2025Something you don't see every day! Digitizing the human proteome in >53,000 individuals with 15-year follow-up and, with machine learning, unraveling nearly 500 disease-causing proteins www.cell.com/cell/fulltex... open-access 7404103
Reposted by Sonali J. Bracken, MD, PhDScience News @scinews.bsky.social · 23/12/2024Happy Holidays!💐 Credit to: Dario Brunetti 013734
Reposted by Sonali J. Bracken, MD, PhDMark Cuban @mcuban.bsky.social · 10/12/2024If you want to understand why healthcare pricing is horrific, the first thing to know is that our system puts 100% of the credit risk for deductibles, copays and co-insurance on hospitals and doctors. That's insane. We have turned them into Sub Prime Lenders 🧵 2081476679749
Sonali J. Bracken, MD, PhD @sjbracken.bsky.social · 08/12/2024Happy holidays from the Duke Rheum crew ❄️ ⛄️ 🎄 @mithurheum.bsky.social 171
Reposted by Sonali J. Bracken, MD, PhDMichal Caspi Tal, PhD @immunofever.bsky.social · 03/12/2023There is a human tissue that builds itself up and breaks itself down every 28 days (on average) using non-scarring wound healing and instead of studying that and learning everything we can about it we think it's gross and look for other less relevant models to understand wound healing. 6439102
Sonali J. Bracken, MD, PhD @sjbracken.bsky.social · 20/11/2024The MITIGATE trial of inebilizumab (aCD19 mAb) for IgG4-RD should get us thinking about which rheumatologic diseases do/don’t warrant deep B cell depletion (i.e. CAR Ts) ⬇️ flares ⬆️ GC-free remission (note rapid steroid taper in placebo group) ⬆️ infections & cytopenias www.nejm.org/doi/full/10....nejm.orgInebilizumab for Treatment of IgG4-Related Disease | NEJMIgG4-related disease is a multiorgan, relapsing, fibroinflammatory, immune-mediated disorder with no approved therapy. Inebilizumab targets and depletes CD19+ B cells and may be effective for treat... 021
Reposted by Sonali J. Bracken, MD, PhDMithu Maheswaranathan, MD @mithurheum.bsky.social · 18/11/2024🆕 #ACR24 | Updated Guidelines for Lupus Nephritis Treatment & Management 🫘 Highlights 🔶 • Critical role of renal biopsy • Differences for treatment by LN Class • Adjunctive Rx w/ HCQ & RAASi • GC pulse ⇢ *moderate/low* dose PDN #Lupus #NephSky #RheumSky #Rheumatology #MedSky 05725
Sonali J. Bracken, MD, PhD @sjbracken.bsky.social · 19/11/2024It was a wonderful #ACR24 and I am truly honored to have received the Distinguished Fellow Award from the American College of Rheumatology this year 1131
Sonali J. Bracken, MD, PhD @sjbracken.bsky.social · 19/11/2024First-of-its kind evidence in severe dSSc demonstrates that CD19 CAR T may both stabilize/improve: 🔶 Fibrotic organ dysfunction 🔶 Vascular dysfunction (as marked by ⬇️ in RP severity and digital ulcerations) 🔶 Grip strength, contractures, and hand function www.thelancet.com/journals/lan... 030