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SimThyrTeam

@simthyrteam.bsky.social

Current news on #thyroid #homeostasis and the award-winning physiological simulation software #SimThyr simthyr.sf.net

SimThyrTeam @simthyrteam.bsky.social · 05/03/2026

30 years of #SimThyr in #Marchintosh 2026: #SimThyr 2.0 on a Mac SE with Mac OS Antares 6.0.7 and SimThyr 4.0.6 on a MacBook Air with macOS Ventura 13.7. Thanks to the fact that the code was based on the #Pascal programming language, the software is highly portable, but runs with full native speed.

SimThyr 2.0 on a Mac SE with Mac OS Antares 6.0.7 (left) and SimThyr 4.0.6 on a MacBook Air with macOS Ventura 13.7 (right)

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SimThyrTeam @simthyrteam.bsky.social · 31/05/2025

Computer simulations with #SimThyr enhance our understanding of the physiology of hypothalamic-pituitary-thyroid feedback control. This applies, for example, to the evolution of #TACITUS syndrome. #thyroid #hypothyroidism #NTIS #biocybernetics doi.org/10.1007/978-...

Figure from the book "Hypothyroidism: A Paradigm Shift" by Hoermann and Dietrich: Combination of peripheral and central mechanisms leading to the low-T3 syndrome. The activities of peripheral (GD1) and central (GD2) deiodinases diverge to cause the low-T3 phenotype. The graph shown has been produced by computer simulation with the free app SimThyr.

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