A Nature Reviews Neuroscience perspective suggests hippocampal acetylcholine serves as a learning signal, tracking prediction errors to update brain models during memory and learning.

Predictive models have emerged as a normative lens for understanding neural function. In this Perspective, de Cothi, Shipley and Barry plausibly unify the diverse roles of hippocampal acetylcholine in...

Your brain is a mapmaker, a memory keeper, and — sometimes — in need of repair. Join neuroscientists Caswell Barry and Holly Gregory for two pint-sized tal…

Your brain is a mapmaker, a memory keeper, and — sometimes — in need of repair. Join neuroscientists Caswell Barry and Holly Gregory for two pint-sized tal…

Your brain is a mapmaker, a memory keeper, and — sometimes — in need of repair. Join neuroscientists Caswell Barry and Holly Gregory for two pint-sized tal…

Your brain is a mapmaker, a memory keeper, and — sometimes — in need of repair. Join neuroscientists Caswell Barry and Holly Gregory for two pint-sized tal…

Shipley et al. show that spatial memory deficits in an Alzheimer’s mouse model are associated with place cell instability and degraded reactivations in rest. Although reactivation rates are preserved,...

Memory dysfunction in Alzheimer’s disease may be linked to impairment in how the brain replays our recent experiences while we are resting, according to a new study in mice by UCL scientists.

School Reading List Children's Books of the Year 2025. To take part, vote for one book in each category and press 'submit' at the end of this form. For more information, book synopses and purchasing ...

Alzheimer's disease (AD) is characterised by progressive memory decline associated with hippocampal degeneration. However, the specific physiological mechanisms underlying hippocampal dysfunction in A...

The successor representation has emerged as a powerful model for understanding mammalian navigation and memory; explaining the spatial coding properties of hippocampal place cells and entorhinal grid ...

The ability to use subjective, latent contextual representations to influence decision-making is crucial for everyday life. The hippocampus is hypothesized to bind together otherwise abstract combinat...