iiinova — where your digital self keeps evolving

Şeyma ⚡️

@seymss.bsky.social

36 followers 58 following 0 posts

PGY-2 in Internal Medicine/Nephrology

Posts Replies Media

Reposted by Şeyma ⚡️

NEJM.org @nejm.org · 04/06/2026

In adults without diabetes who had chronic kidney disease, the nonsteroidal mineralocorticoid receptor antagonist finerenone led to a slower decrease in the estimate glomerular filtration rate than placebo over 32 months. Full phase 3 FIND-CKD trial results: nej.md/4wWOFV4 #ERA26

Graph comparing mean eGFR slopes between finerenone and placebo groups. The chart has three sections: Total, Baseline to Month 3, and Month 3 to End of Treatment. Numerical values are provided above the bars, showing treatment differences with confidence intervals.

0126 0

Reposted by Şeyma ⚡️

NEJM.org @nejm.org · 27/05/2026

An interim analysis of a phase 3 trial involving patients with IgA nephropathy showed that 39 weeks of treatment with telitacicept led to a greater reduction in the 24-hour urinary protein-to-creatinine ratio than placebo. Full TELIGAN trial results and Research Summary: nej.md/4uFpMLz

This image contains part of the research summary from an article in the New England Journal of Medicine about a phase 3 trial on telitacicept for IgA nephropathy. It includes a diagram showing the how telitacicept works. A graphic below compares telitacicept and placebo groups, each with 159 participants. The patient demographics are 318 adults, with an average age of 38 years, and a gender distribution of 54% women and 46% men. There's a prompt to read the full research summary at NEJM.org.

043 0

Reposted by Şeyma ⚡️

NEJM.org @nejm.org · 04/03/2026

In adults with type 1 diabetes and chronic kidney disease with albuminuria, the decrease in the urinary albumin-to-creatinine ratio was significantly greater with finerenone than with placebo. Full phase 3 FINE-ONE trial results: nej.md/4rTPAmu #MedSky #EndoSky #Nephrology

Original Article | MAR 11, 2026
Finerenone in Type 1 Diabetes and Chronic Kidney Disease (FINE-ONE)
Figure 1. Change in the Urinary Albumin-to-Creatinine Ratio.

11010 0

Reposted by Şeyma ⚡️

NEJM.org @nejm.org · 14/02/2026

ORIGIN 3 trial: In at least half of patients, IgA nephropathy progresses to kidney failure or death within 10 to 20 years after diagnosis. The investigational drug atacicept might offer a new treatment option. Research findings are summarized in a new Quick Take video. nej.md/3OfUv1W #MedSky

A visual representation of the ORIGIN 3 trial, in which researchers assessed the efficacy and safety of atacicept in patients with IgA nephropathy.

0153 0

Reposted by Şeyma ⚡️

ASN Publications @asnpublications.bsky.social · 30/12/2025

What are the latest insights on treating hepatorenal syndrome? Read this #ASNJASN Clinical Nephrology Insight article: kidney.pub/JASN0920

051 0

Reposted by Şeyma ⚡️

ASN Publications @asnpublications.bsky.social · 07/11/2025

Now live in #ASNJASN, simultaneously published with #KidneyWk: "Immunosuppression in Older Kidney Transplant Recipients: A Randomized Controlled Trial" Read more: kidney.pub/JASN0924

176 0

Reposted by Şeyma ⚡️

Sena Cetin @cetinsz.bsky.social · 07/11/2025

Such an honor to present this work with our fantastic team! Exciting times for single-cell and kidney research 🔬💪 #KidneyWk #NephSky

061 0

Reposted by Şeyma ⚡️

NEJM.org @nejm.org · 06/11/2025

ORIGIN phase 3 trial: In an interim analysis of a clinical trial, atacicept, a fusion protein that binds and inhibits two cytokines thought to be central to the pathophysiology of IgA nephropathy, significantly reduced proteinuria. nej.md/3JEq8QL @asnkidney.bsky.social | #KidneyWk

American Society of Nephrology Kidney Week 2025
Original Article | Nov. 6, 2025 | NEJM.org
A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy

Figure 2A. Change from Baseline in 24-Hr Urinary Protein-to-Creatinine Ratio through Week 36.

The NEJM identity sits at the bottom.

01910 0

Reposted by Şeyma ⚡️

Joel Topf @kidneyboy.bsky.social · 06/11/2025

Next up in Richard Lafayette about Ataracept in IgAN #KidneyWk

182 0

Reposted by Şeyma ⚡️

Joel Topf @kidneyboy.bsky.social · 21/06/2025

Oh look, a list of the 30 best nephrology podcasts. www.millionpodcasts.com/nephrology-p...

millionpodcasts.com

Best 30 Nephrology Podcasts

Best Nephrology Podcasts to Listen to ⋅ 1. Freely Filtered, a NephJC Podcast ⋅ 2. Kent's Kidney Stories ⋅ 3. Channel Your Enthusiasm ⋅ 4. Clinical Journal of the American Society of Nephrology (CJASN)

2209 0

Reposted by Şeyma ⚡️

The Clinical Problem Solvers @cpsolvers.bsky.social · 05/04/2025

🚨Join us this Monday, April 7th at 6AM PST/9AM EST for an expert-led Nephrology VMR session featuring nephrology experts from Duke University! 🩺🧑‍⚕️ See you there! Use the link➡️ clinicalproblemsolving.com/learn-live/ #MedEd #MedSky #Nephrology

041 0

Reposted by Şeyma ⚡️

The Clinical Problem Solvers @cpsolvers.bsky.social · 04/04/2025

🚨New Schema Podcast Episode🚨 Tune in as @madellenaconte.bsky.social , @saklawimd.bsky.social and @asanchez.bsky.social walk us through their bradycardia schema as they tackle a case of bradycardia presented by Noah! 🫀🩺 Use the link➡️ clinicalproblemsolving.com/2025/04/03/e... #ClinicalReasoning

054 0

Reposted by Şeyma ⚡️

The Clinical Problem Solvers @cpsolvers.bsky.social · 23/03/2025

🚨New Spaced Learning podcast episode out NOW!!🚨 Dive into a structured approach to hemoptysis and sharpen your clinical reasoning skills. 🫁🫀 Listen now!🎧➡️ clinicalproblemsolving.com/2025/03/23/e... #MedSky #ClinicalReasoning #MedEd

172 0