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sergiocatz1.bsky.social

@sergiocatz1.bsky.social

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sergiocatz1.bsky.social @sergiocatz1.bsky.social · 20/06/2026

Delighted that our collaborative work with the Albricht lab is now published in Nature Cell Biology

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Reposted by @sergiocatz1.bsky.social

Scripps Research @scripps.edu · 06/04/2026

In a new @natchembio.nature.com study, Scripps Research scientists report first-in-class compounds that block a key protein interaction in immune cells, reducing inflammatory signaling in autoimmune disease without compromising immune defense.

ow.ly

Study shows new drug compounds dial down inflammation without compromising immunity

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sergiocatz1.bsky.social @sergiocatz1.bsky.social · 06/04/2026

We are delighted that our article "Munc13-4–STX7 inhibitors impair endosomal TLR activation and systemic inflammation" is now published online in Nature Chemical Biology. Please see our discovery of ENDOtollins here: rdcu.be/fbU78

rdcu.be

Munc13-4–STX7 inhibitors impair endosomal TLR activation and systemic inflammation

Nature Chemical Biology - Endosomal Toll-like receptors (TLRs) are central to the innate immune response but their overactivation can cause systemic inflammation and disease. Now, new small...

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