Inequalities exist in hospitalisation rates, which are undesirable and costly for health systems; with higher rates in populations with lower levels of income, education or residing in socioeconomical...

YouTube video by Dementia Researcher

This study uses prospectively collected data from the ABCD study to assess the relationship between longitudinal patterns of social media use (hours per day) and cognitive performance after 2 years in...

For the first time, reductions in cerebral β-amyloid pathology load and rate of cognitive and functional decline have been achieved in Alzheimer's disease, through pharmacological intervention in rand...

Willem van Gool and colleagues argue that moves to use blood biomarkers in clinical practice or population screening are inappropriate without evidence on outcomes important to patients and carers T...

Molecular Psychiatry - Key questions for the future of amyloid research in dementia: a framework for integrating complex datasets

A recent trial presented at the ESC meeting addresses the question of reducing blood pressure meds in the elderly. It’s an important study—for numerous reasons.

The clustering of dementia risk factors is common and has implications for policies targeting risk reduction.To estimate the prevalence of 16 dementia…

By analysing the smartphone data of 2,112,288 participants, in particular observing and comparing the activity of the same individual in two different environments, we find that increases in the walka...

In this Perspective, Sahar Sadjadi and colleagues discuss the imperative for incorporating social sciences into medical research, education and implementation.

INTRODUCTION We addressed whether higher education plays a causal role in reducing dementia risk by comparing two indices of cognitive reserve: education and young adult general cognitive ability (G...

Objectives To ascertain the balance of dementia risk reduction policies in England, considering their reach (population-wide vs targeted at specific individuals) and agency (the level of resource requ...

Our warts-and-all account of what it's like to do public health research.

It’s never too early – or late – to protect your brain. Research shows dementia prevention could begin as early as childhood.

A US study shows that many research participants don’t want to know their risks of getting Alzheimer’s disease.

This Viewpoint examines the use of blood-based biomarkers to test for Alzheimer disease and outlines why they should not be the first or only tool used in screening for cognitive impairment.

BACKGROUND Understanding cognitive decline trajectories is crucial for dementia prevention, as many cases go undetected. Identifying participation biases in such studies is essential for data validi.....

In a community-based cohort of more than 2,000 older adults from Sweden, blood biomarkers for Alzheimer’s disease were able to predict dementia up to 16 years before disease onset.

Nature - Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a...

INTRODUCTION Knowledge gaps remain about the prognosis of mild cognitive impairment (MCI). Conversion rates to dementia vary widely, and reversion to normal cognition has gained attention. This revi...

Population-level policies that target risk factors for dementia save money and give people extra years in good health, a modelling study found.

This Viewpoint discusses age-specific dementia prevalence rates, their decline during 40 years, and the subsequent effect on dementia incidence.

Find out more about taking a population based approach to reduce risk of dementia and music therapy for dementia patients

Children born in poverty are more likely to experience poverty as adults, but this likelihood is greater in the United States than in Australia, Denmark, Germany or the United Kingdom. The authors exa...

Discover population-level approaches to dementia risk reduction (PLADRR): what they are, how they work, and why they matter.

Background and ObjectivesThe Systolic Blood Pressure Intervention Trial suggested that intensive lowering of systolic blood pressure (SBP) decreases the risk of developing dementia. However, an insuff...

This cohort study determines if South African regulations restricting sodium content in processed foods were associated with reductions in sodium consumption and blood pressure among rural South Afric...

Super-featherweight boxer John Cooney is in intensive care after his defeat by Welshman Nathan Howells in Belfast on Saturday.

Recent regulatory approvals of three amyloid-lowering monoclonal antibody therapies for the treatment of Alzheimer's disease (AD) have triggered a polarizing debate in the field on the clinical mean...

INTRODUCTION We explored which dementia risk factors in two multidomain prevention trials mediate beneficial, neutral, or counteracting effects on dementia incidence. METHODS We pooled data from t...

Intrinsic capacity includes a person’s mental and physical capacities. The authors examined cohort trends in intrinsic capacity in two large English and Chinese studies. They report that more recently...

A cohort study of over 15,000 US adults found that the lifetime risk of developing dementia from ages 55 to 95 is 42%, with the highest risk in APOE ε4 carriers, women and Black adults, and projected ...

Dementia is a major global public health challenge, with over 50 million cases in 2020, projected to reach 152 million by 2050. Effective prevention s…

Dementia is largely excluded from discussion of noncommunicable diseases, which limits its inclusion in health policies and allocation of resources — yet it is already a leading cause of mortality and...