iiinova — where your digital self keeps evolving

Scheff Research Lab @schefflab.bsky.social · 24/07/2026

🎉 Congrats to Chelsea Gelboin-Burkhart, MD for receiving the American Head and Neck Society grant! This funding will allow us to expand our collaboration to deepen our understanding of the communication between nervous and immune systems. #cancerneuroscience

AHNS banner featuring clinicians reviewing a skull x-ray

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Scheff Research Lab @schefflab.bsky.social · 25/02/2026

Loved having (almost) the whole lab in attendance at the #CancerNeuro26 meeting in Houston last week! Such a great meeting full of catching up with friends and building new collaborations! Big thanks to Wiley’s #AdvancedPortfolio for continuing to support the #cancerneuroscience field.

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Scheff Research Lab @schefflab.bsky.social · 28/01/2026

Our own @andremartel.bsky.social, 4th yr grad student, is honored to be recognized and receive the Professional Development Award as an early-career scientist and attend the 2026 International Cancer Neuroscience Symposium in Houston, TX, USA! #CancerNeuro26 #TravelAwardRecipient #AdvancedPortfolio

Professional Development Award Recipient Poster featuring neuron in background and details for the 2026 International Cancer Neuroscience Symposium in Texas, Feb 18-20 & sponsored through MD Anderson Cancer Center and Wiley Advanced

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Scheff Research Lab @schefflab.bsky.social · 22/10/2025

2026 Cancer Neuroscience Symposium Abstract submission deadline: 11.7.2025 This is one of my favorite meetings of the year where all the science is really great and so much collaboration that starts within those couple days. Even if you're on a cusp of the field, totally worth checking out!

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Scheff Research Lab @schefflab.bsky.social · 23/09/2025

The NOA has landed! We have our first 🛏️to 🔬 to🛌translation! In collaboration with Glycyx Therapeutics, we received funding for a multi-institutional clinical trial to test if peripheral acting OPRM1 antagonism can improve response to immune checkpoint blockade in head and neck cancer patients!

Here is the work that got us to this point: https://jitc.bmj.com/content/12/11/e009962

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Scheff Research Lab @schefflab.bsky.social · 19/08/2025

The Scheff Lab image was selected to be the background of the @pcpr-pittpain.bsky.social seminar series poster highlighting mammary innervating dorsal root ganglia neurons. This image was taken in a study understanding the impact of sensory neurons on breast cancer progression and (lack of) pain.

Dorsal root ganglia neurons stained with green, blue, and pink dyes.

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Scheff Research Lab @schefflab.bsky.social · 08/05/2025

🎉Congratulations to @andremartel.bsky.social for winning BEST POSTER at yesterday's #painday, held at the University of Pittsburgh @cnup.bsky.social! Thanks to Hannah and @nehamokhasi.bsky.social for their excellent contributions.

Graduate student Andre Martel Matos stands next to his poster entitled: Sympathetic Neurotransmission Contributes to Oral Cancer-Induced Spontaneous Pain.

Hannah White presents her poster entitled: Sensory Innervation in the Tumor Microenvironment of Breast Cancer.

Certificate awarding Andre Martel Matos with Best Poster Presentation in Pre-Clinical Research (predoctoral) category.

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Scheff Research Lab @schefflab.bsky.social · 06/05/2025

Thanks to @usasp.bsky.social for a great conference! Dr Scheff discussed reverse translation in #cancerpain and presented a poster detailing new work on radiation-induced pain and oral mucositis. @andremartel.bsky.social presented updates on his project on sympathetics and cancer pain. #research

Graduate student Andre Martel Matos presents his poster entitled "Sympathetic Neurotransmission Contributes to Oral Cancer-Induced Spontaneous Pain" to several conference attendees

Dr Nicole Scheff presents research poster entitled "Temporal characterization of radiation-induced oral pain using a mouse model" to two conference attendees

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Scheff Research Lab @schefflab.bsky.social · 07/03/2025

@andremartel.bsky.social and I had an awesome time teaching at the inaugural Cold Spring Harbor Laboratory 2025 Methods in Cancer Neuroscience course this week! #cshl #cancerneuroscience. Wish we could have stayed but had to be home for the Stand Up For Science Event! @standupforscience.bsky.social

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Scheff Research Lab @schefflab.bsky.social · 30/01/2025

📢New publication out: Sensory Neurotransmission and Pain in Solid Tumor Progression! This review article by first author @andremartel.bsky.social details recent work on the bidirectional relationship between sensory neurons and #cancer cells. authors.elsevier.com/sd/article/S... #neurobiology

Proposed cycle between nociceptive input and autonomic output in cancer. Sensitization of nociceptive sensory neurons by the tumor microenvironment leads to propagation of orthodromic signaling towards the central nervous system (CNS).

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Scheff Research Lab @schefflab.bsky.social · 21/11/2024

📢Check out our new publication, Morphine treatment restricts response to immunotherapy in oral squamous cell carcinoma, out now in the Journal for ImmunoTherapy of Cancer! This article presents urgent work with implications for improving ICI therapy responses. jitc.bmj.com/content/12/1...

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