Sanford Burnham Prebys @sbpdiscovery.bsky.social · 22/09/2026Congratulations to the five early career scientists at Sanford Burnham Prebys who were recognized at the 25th annual Fishman Fund awards ceremony. The Fishman Fund supports promising researchers as they build their scientific careers. sbpdiscovery.org/ceremony-cel... 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 19/08/2026In two back-to-back studies published in Genes & Development, a team led by Anindya Bagchi, PhD, uncovered a new framework for understanding how the PVT1 region regulates MYC activity. sbpdiscovery.org/press/resear... @anindyabagchi.bsky.social 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 12/08/2026A study from the Tharp lab and collaborators in #ScienceAdvances finds that nearby conditions and nutrients influence how cancer cells evade the immune system and reveals a potential way to stop this protection. sbpdiscovery.org/press/stripp...sbpdiscovery.orgStripping away what conceals cancer cells from our immune system - Sanford Burnham PrebysStudy from the Tharp lab finds nearby conditions and nutrients govern how cancer cells avoid immune cells, and how to stop this protection. 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 24/07/2026New research from the Boutros lab, published in BMJ Oncology, found that protein levels differ in lung tumors from men and women. Lung cancer also showed more sex-related protein differences than any other cancer type studied. sbpdiscovery.org/press/biolog... @chenghaozhu.bsky.socialsbpdiscovery.orgBiological sex linked to protein changes in lung adenocarcinoma and other cancers - Sanford Burnham PrebysStudy shows lung adenocarcinoma has strong sex-based proteome differences, while five other cancer types have moderate differences. 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 23/07/2026With Alzheimer’s, tau proteins form noxious knots and gradually disrupt the brain circuits they would otherwise preserve. The Huang lab showed in #ScienceAdvances that a different protein called SORLA offers protection against the effects of these lethal loops. sbpdiscovery.org/press/protec... 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 20/07/2026Sanford Burnham Prebys mourns the loss of T. Denny Sanford, whose visionary philanthropy helped shape our Institute and advance biomedical research. sbpdiscovery.org/t-denny-sanf...sbpdiscovery.orgT. Denny Sanford (1935-2026) - Sanford Burnham PrebysRenowned philanthropist and businessman T. Denny Sanford passed away July 18, 2026 in his hometown of Sioux Falls, South Dakota. He was 90 years old. 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 13/07/2026We’re excited to welcome Jill Mesirov, PhD, to Sanford Burnham Prebys as Distinguished Professor and Senior Vice President for Computational Science. sbpdiscovery.org/press/pionee... 000
Reposted by Sanford Burnham PrebysHealthcare in Europe @healthcare-europe.bsky.social · 05/07/2026Why does #prostatecancer in some patients grow slowly and remain localized while it becomes aggressive and metastasizes in others? In a new paper led by 🇺🇸 @sbpdiscovery.bsky.social, researchers identify the answer: #tumor methylation. 122
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 17/06/2026Kevin Tharp, PhD, was awarded a 3 year, $450,000 Ovarian Cancer Research Alliance grant. Tharp will use the new funding to follow up on research findings regarding how high grade serous ovarian cancer circumvents the immune system’s anti-tumor defenses. sbpdiscovery.org/kevin-tharp-...sbpdiscovery.orgKevin Tharp awarded $450,000 Ovarian Cancer Research Alliance grant to break down tumor defenses - Sanford Burnham PrebysThe new award will fund research regarding how to bust through the barrier between tumors and immune cells. 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 11/06/2026What can we learn from people who live past 100 in good health? Researchers from the U.S. and Europe gathered at Sanford Burnham Prebys to share new findings from the CIAO Study, an ongoing effort to uncover the secrets of healthy aging and longevity. 🧬🌿 sbpdiscovery.org/press/ciao-s...sbpdiscovery.orgCIAO Study: 11th annual longevity symposium provides new peeks and possibilities at longer, healthier lives - Sanford Burnham PrebysThe Cilento Initiative on Aging Outcomes (CIAO) held its 11th annual research symposium at Sanford Burnham Prebys, with more than a dozen scientists and physicians from Europe and the US presenting ne... 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 03/06/2026🎓 Congratulations to the newest graduates of the Sanford Burnham Prebys Graduate School of Biomedical Sciences! We're proud to welcome these talented scientists to our alumni community and look forward to celebrating their achievements in the years ahead. sbpdiscovery.org/sanford-burn...sbpdiscovery.orgSanford Burnham Prebys recognizes 10 doctoral degree recipients - Sanford Burnham PrebysThe Institute’s Graduate School of Biomedical Sciences held its third Commencement ceremony to celebrate new alumni. 030
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 02/06/2026Launching 50 for 50: 50 discoveries from 50 years at Sanford Burnham Prebys. Some transformed fields. Some opened doors others walked through. All worth knowing. More stories coming. sbpdiscovery50.org/50-for-50/ 020
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 22/05/2026Cholesterol-craving cancers need lipid enzymes to use metabolites for growth |Study finds kinases move cholesterol in the cell to where it can activate a growth pathway in many aggressive cancers. The @bemerling.bsky.social Emerling lab published in #ScienceAdvances. sbpdiscovery.org/press/choles... 021
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 16/04/2026The Freeze lab and an international team of collaborators discovered a new rare genetic disease that interferes with brain development. They published findings in @hggadvances.bsky.social that identify the faulty mutated gene and show how it interferes with normal cellular function. bit.ly/4vul3h3sbpdiscovery.orgResearchers identify new genetic disease that interferes with brain development - Sanford Burnham PrebysStudy from the Freeze lab finds that a mutation destabilizes proteins involved in how children grow and mature. 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 10/03/2026Nearly 40% of U.S. adults have metabolic syndrome, a condition that can lead to liver damage and fibrosis. A new study from Sanford Burnham Prebys highlights LARP6, an RNA-binding protein that helps drive fibrosis and may be a promising therapeutic target. sbpdiscovery.org/press/living... 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 02/03/2026Thank you to The San Diego Union-Tribune for helping share the story of Sanford Burnham Prebys as we mark 50 years of discovery and impact. We’re grateful for the spotlight on the people, science and community that have shaped our Institute since 1976. www.sandiegouniontribune.com/2026/02/27/a...sandiegouniontribune.com‘A novel approach’: Sanford Burnham Prebys celebrates 50 years of medical explorationThe La Jolla-based research institute continues its founding principle of collaboration across multiple fields 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 13/02/2026An international team including the Kaufman lab published in Nature.com showing that liver cell stress can both drive cancer and make tumors less resistant to immunotherapy. The findings may help physicians identify which patients are most likely to benefit from existing treatments. 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 12/02/2026Today, on International Day of #WomenAndGirlsInScience, we gathered for the latest Women in Science Lecture Series. Thank you for the thoughtful and engaging conversation Cheryl Anderson, PhD, MPH, MS and Angela Liou, MD. Grateful to everyone who joined us. #InternationalDayOfWomenAndGirlsInScience 010
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 04/02/2026Sanford Burnham Prebys scientists published in @cp-cellreports.bsky.social showcasing a new approach for measuring the activity of enzymes linked to cell death and a more complicated picture where protein activation cannot always be presumed by protein production. sbpdiscovery.org/press/metall... 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 02/02/2026Join us on February 11 for the next event in the Women in Science Lecture Series at Sanford Burnham Prebys, featuring a lecture and fireside chat that highlight the groundbreaking work and perspectives of women leaders in biomedical science. Must RSVP to attend: lnkd.in/gzkXQRrm 010
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 30/01/2026Advancing Together: 50 Years of Sanford Burnham Prebys - For 50 years, bold ideas, dedicated scientists, and a shared commitment to discovery have shaped who we are today. Join us as we celebrate this milestone year and look ahead to the next 50. youtu.be/Q4hNMzBq7N0?... 010
Reposted by Sanford Burnham PrebysEpigenetics Podcast @epigeneticspod.bsky.social · 19/01/2026In this episode of the Epigenetics Podcast, we talked with Will Wang from @sbpdiscovery.bsky.social about his work on muscle stem cell repair, regeneration, and aging, exploring spatial-omics and machine learning. #podcast #epigenetics Listen here: activemotif.com/podcasts-wil... 063
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 18/11/2025New research from Sanju Sinha, PhD, introduces DeepTarget, a tool that predicts both primary and secondary targets of cancer drugs. It could help repurpose existing medicines for more patients. sbpdiscovery.org/press/comput... 010
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 07/11/2025Meet Rouven Arnold, PhD, a postdoc in Peter Adams’ lab at Sanford Burnham Prebys. He studies how aging changes our cells—with the goal of preventing diseases like heart disease, cancer, and dementia. Learn what drives his work and his path into science. ➡️ bit.ly/47PtecX bit.lyQ & A with Postdoctoral Researcher Rouven Arnold, PhD, from the Adams Lab - Sanford Burnham PrebysMeet one of our early-career scientists: Rouven Arnold, PhD 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 03/11/2025Scientists at Sanford Burnham Prebys, the University of Minnesota and Duke University report in Nature that “biased modulators” can target GPCRs more precisely—expanding potential drug targets and reducing side effects. www.nature.com/articles/s41... 122
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 23/10/2025“Once we find the players that drive disease, we can find drugs to help,” says Sanjeev Ranade, PhD. New study reveals a key protein linked to heart defects in Down syndrome. 🧬❤️ sbpdiscovery.org/press/huntin... 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 16/10/2025🧬 Biomedical Sciences PhD Applications Now Open! Do you want to explore the science behind human health and disease? Our program is looking for curious and driven researchers ready to tackle the most pressing questions in biology and medicine. sbpdiscovery.org/education/gr... 010
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 07/10/2025We’re pleased to announce that Paul Boutros, PhD, MBA, has been named the new director of the National Cancer Institute (NCI) designated cancer center at Sanford Burnham Prebys Medical Discovery Institute. Read all about it! sbpdiscovery.org/press/paul-b... 020
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 02/10/2025👏 Congratulations to Xueqin Sherine Sun, PhD, on receiving a $600,000 grant from the V Foundation for Cancer Research to study glioblastoma, one of the most common and deadly brain cancers. sbpdiscovery.org/xueqin-sun-a... 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 25/09/2025What connects survival, science + diabetes care? Adam Heller, PhD. At 92, this Holocaust survivor, scientist + engineer shares how his innovations changed how millions manage diabetes. 🎙️Hear his remarkable story in Episode 5 of the podcast. 👀On YouTube: youtu.be/TEhPlF29yl4?... 110
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 16/09/2025Today, 62 National Cancer Institute (NCI)–Designated Cancer Centers issued a joint statement underscoring the importance of HPV vaccination. #HPVvaccine #HPVvax #EndHPVCancers 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 10/09/2025🔬 New research from the @anideshpande.bsky.social Deshpande lab at Sanford Burnham Prebys. The study demonstrates how public genomic screening data can be used to uncover a new genetic vulnerability in synovial sarcoma. 👏 Shout out to Rema Iyer, PhD lead author of the manuscript. 111
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 14/08/2025For decades, scientists thought MYOD was just a muscle-builder. But new research from Sanford Burnham Prebys shows this gene has a Jekyll-and-Hyde side—able to switch from activating muscle genes to silencing them. sbpdiscovery.org/press/muscle... 021
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 05/08/2025Proud to host six high school interns from the Preuss School for a hands-on research experience at Sanford Burnham Prebys. 👏 Thanks to Peggy & Peter Preuss and Debby & Wain Fishburn for making it possible! sbpdiscovery.org/preuss-schoo...sbpdiscovery.orgPreuss School interns wrap up unforgettable research experience - Sanford Burnham PrebysAspiring biomedical researchers and health care professionals gained hands-on research training at Sanford Burnham Prebys. 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 02/08/2025New research from the Marth Lab: Most blood glycoproteins are easy to spot—but finding the rare ones is like searching for Waldo across every book. 🧠🧬 🔗 Read more: sbpdiscovery.org/press/signal... #Biomedicine #SanfordBurnhamPrebys #NatureCommunications #Science 010
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 30/07/2025Meet Meena Sudhakaran, PhD, a postdoc in the Kersten Lab at Sanford Burnham Prebys. She’s advancing cancer immunology to improve immunotherapy for breast cancer. Read more about her journey into science: sbpdiscovery.org/q-and-a-with... #CancerResearch #PostdocLifesbpdiscovery.orgQ & A with Postdoctoral Researcher Meena Sudhakaran, PhD, from the Kersten Lab - Sanford Burnham PrebysMeet one of our early-career scientists: Meena Sudhakaran, PhD. She studies cancer immunology to improve immunotherapy for breast cancer. 000
Reposted by Sanford Burnham PrebysThe American Journal of Pathology @ajpathology.bsky.social · 29/07/2025#ArticleinPress: Peroxisome Proliferator-activated Receptor Agonist IVA337 Alleviates Inflammation and Fibrosis in MASH by Restoring Lipid Homeostasis. @ucsandiego.bsky.social and @sbpdiscovery.bsky.social. #OpenAccess text: ajp.amjpathol.org/article/S000...ajp.amjpathol.orgPeroxisome Proliferator-activated Receptor Agonist IVA337 Alleviates Inflammation and Fibrosis in MASH by Restoring Lipid HomeostasisMetabolic dysfunction-associated steatohepatitis (MASH), an advanced stage of metabolic dysfunction-associated steatotic liver disease (MASLD), is characterized by significant hepatic fibrosis and inf... 031
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 26/07/2025A promising advance for pancreatic cancer published Cancer Cell: Blocking macropinocytosis reduces fibrosis around pancreatic tumors, improving immune cell access & boosting response to chemo & immunotherapy in mice. sbpdiscovery.org/press/reshap... @cosimocommisso.bsky.social @yijuan.bsky.social 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 16/07/2025Big congrats to grad students Aashna Lamba & Ashley Neil at @SBPdiscovery—named 2025 CIRM Predoctoral Fellows! 🌟 Lamba’s research could help hearts heal after injury ❤️ Neil is exploring brain inflammation in Alzheimer’s 🧠 #SanfordBurnhamPrebys #RegenerativeMedicine #CIRM #STEM 020
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 02/07/2025📣 Welcome Michael Karin, Ph.D., to Sanford Burnham Prebys! He joins as director of the new Center for Metabolic and Liver Diseases and will continue his pioneering work on chronic inflammation and cancer. sbpdiscovery.org/press/leadin...sbpdiscovery.orgLeading cancer and metabolic disease expert Michael Karin joins Sanford Burnham Prebys - Sanford Burnham PrebysKarin will direct the Center for Metabolic and Liver Diseases and continue his studies on inflammation and cancer. 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 25/06/2025What if the key to major medical breakthroughs is already sitting in clinical databases—just waiting to be unlocked? Sanford Burnham Prebys CEO David Brenner shares why tapping into electronic health records could transform research and care. Read more: www.sandiegouniontribune.com/2025/06/23/o...sandiegouniontribune.comOpinion: Health database could provide key insights to improve careIn every body and in everybody, there is an enormous, diverse and changing array of medical and health information, from longitudinal data like our weight and blood pressure over the years to the b… 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 05/06/2025Cheers to the newest grads of the Sanford Burnham Prebys Graduate School of Biomedical Sciences! 🎓🔬♥️ Their hard work, perseverance, and curiosity reflect the spirit of our graduate program's motto: “Knowledge is the power to heal.” Congrats to these rising scientists. More: bit.ly/3HFmyEBbit.lySanford Burnham Prebys celebrates newest graduate school alumni - Sanford Burnham PrebysThe Graduate School of Biomedical Sciences held its 2025 Commencement ceremony to celebrate four recent graduates. 001
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 04/06/2025🧠 Could HIV drugs help lower #Alzheimer’s risk? New research from Sanford Burnham Prebys, led by Jerold Chun, MD, PhD, found that patients taking #HIV drugs blocking #reversetranscriptase had fewer cases of Alzheimer’s—pointing to a potential drug target. More: bit.ly/4kuxvHU 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 03/06/2025Centenarians in Cilento are thriving thanks to a Mediterranean way of life. The CIAO Study 🌿 reveals they’re biologically younger, with resilient immune systems & strong social ties—offering real clues to how we can all age better. More: bit.ly/45HjqCf #CIAOstudy #longevity #healthyagingbit.lyCIAO Study: Lessons learned on living longer and better (with more to come) - Sanford Burnham PrebysA select group of scientists from around the world gathered in the small town of Acciaroli in the Cilento-Salerno region of Italy to review a decade’s worth of research in the ongoing Cilento Initiative on Aging Outcomes (CIAO), a longitudinal study of local residents 100 years and older. 110
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 31/05/2025Evan Snyder, MD, PhD, professor in the Center for Neurologic Diseases at Sanford Burnham Prebys, was named a Fellow of the Child Neurology Society for his clinical expertise and pioneering research in #pediatricneuroscience and #stemcellbiology. 🧠 Learn more: 🔗 bit.ly/4jATHiobit.lyEvan Snyder named Fellow of the Child Neurology Society - Sanford Burnham PrebysEvan Snyder, MD, PhD, has been named a Fellow of the Child Neurology Society, honoring a distinguished career and significant contributions in the field of child neurology. 010
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 30/05/2025From cancer and aging to immunotherapy and AI, these new PhDs are already making an impact—and they’re just getting started. 👏 Learn more about how we’re training tomorrow’s scientists: vist.ly/3n5mjza #SBPgrad #PhDlife #FutureOfScience #BiomedicalResearch #CancerResearch #Immunotherapy 010
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 30/05/2025The Prebys Foundation has announced a $7M emergency funding package for seven top-tier biomedical research institutions in San Diego, a global hub of scientific innovation, including Sanford Burnham Prebys. Learn more: 🔗 bit.ly/4kiJ84Hbit.lyPrebys Foundation awards $1 million to Sanford Burnham Prebys as part of emergency support to local biomedical research institutions - Sanford Burnham PrebysThe Prebys Foundation announced this week an emergency response package totaling $7 million to seven leading research institutions in San Diego — a global hub and leader in biomedical science and innovation. 011
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 29/05/2025🎙️ Catch Ani Deshpande, PhD, in episode 151 of the @epigeneticspod.bsky.social where he discusses his work on epigenetic regulation in #AML, and the use of #CRISPR and high throughput screens for drug discovery. ▶️ YouTube: vist.ly/3n5jemi ᯤ Spotify: vist.ly/3n5jemj 003
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 28/05/2025Check out our Q&A with scientists and podcasters Ani Deshpande & Pam Itkin-Ansari! Their podcast 𝑇ℎ𝑒 𝐷𝑖𝑠𝑐𝑜𝑣𝑒𝑟𝑦 𝐷𝑖𝑎𝑙𝑜𝑔𝑢𝑒𝑠 is blowing minds—venom, insulin, and Ozempic all in one. 🎧💉 Listen: bit.ly/3Fmu4nlbit.lyScientists and podcasters - Sanford Burnham PrebysSanford Burnham Prebys scientists Ani Deshpande, PhD, and Pamela Itkin-Ansari, PhD, bring dramatic stories of scientific achievement to life. 000
Sanford Burnham Prebys @sbpdiscovery.bsky.social · 20/05/2025Cutting NIH funding means fewer cures, fewer trials, and slower progress. San Diego researchers are speaking out. 🧬 Dr. Kurt Marek of Sanford Burnham Prebys joined the call to protect science. 🔗 www.10news.com/news/local-n... #FundScience #NIH10news.comSan Diego County supervisor & local researchers make voices heard on preserving NIH funding"We are here today to sound the alarm on the devastating cuts and disruptions to the National Institutes of Health,” Supervisor Terra Lawson-Remer said. 000