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SBGrid Consortium @sbgrid.bsky.social · 07/11/2025

How one protein tail helps starve bacteria of zinc: a publication highlight chosen by recent Ph.D. graduate @keandreyam.bsky.social , Ph.D. (congratulations KeAndreya!) from the laboratory of @chazinwalter.bsky.social to highlight. Read more here: buff.ly/UNLUraF #SBGrid #Calprotectin

Left: Structure of the S100A8 (magenta)/S100A9 (cyan) heterodimer of calprotectin bound to zinc ion (sphere). Right: Close-up of the histidine residues (orange) coordinating zinc ion. PDB ID 8SJC. CC BY SBGRID.

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SBGrid Consortium @sbgrid.bsky.social · 17/10/2025

New Title Alert: cryoTIGER- (Tilt Interpolation Generator for Enhanced Reconstruction) in cryo-electron tomographya computational workflow leveraging a deep learning-based frame interpolation to generate intermediate tilt images. Learn more here: buff.ly/j7S8zMZ #SBGrid #SBGridSoftware

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SBGrid Consortium @sbgrid.bsky.social · 15/10/2025

New Title Alert: BindCraft- a user friendly and accurate binder design pipeline. Learn more here: buff.ly/GJJ6wUR #SBGrid #SBGridSoftware #StructuralBiology

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SBGrid Consortium @sbgrid.bsky.social · 28/04/2025

11th NIH R25 Train the Trainer SBGrid Consortium workshop at @harvardmed.bsky.social-this one specifically for the #CryoEM Facility leaders. #RELION & #CryoSPARC in @amazonwebservices.bsky.social (AWS) cloud environment. Melissa Chambers & Daniel Stoddard will co-lead the new CryoACCESS initiative.

Photo of workshop attendees standing on the Harvard Quad green in front of Gordon Hall, large stone columned building

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SBGrid Consortium @sbgrid.bsky.social · 04/12/2024

For our November member tale we caught up with SBGrid member Jens Meiler, who splits his time between laboratories at Vanderbilt University and Leipzig University and offers some perspective around the ongoing AI frenzy. Read more here: buff.ly/3Zf9US9 #StayConnected #ScienceMatters

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SBGrid Consortium @sbgrid.bsky.social · 19/11/2024

SBGrid's Capsules technology is used to isolate the software runtime environment, encapsulating executables, libraries, & version-specific dependencies to provide conflict-free, zero-configuration access to structural biology software. More in Acta Cryst D: journals.iucr.org/d/issues/202...

Image of pill capsule with molecules pouring out made up of elements included in SBGrid software capsules: dependencies, executables, data files, libraries, and executables

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SBGrid Consortium @sbgrid.bsky.social · 07/05/2024

Member Tale: Steven Damo's lab at Fisk University is all about metals and mentorship. Damo examines how metals like zinc & maganese become tools wielded by/against the immune system & how his research can help to nourish a new generation of scientists to diversify STEM. sbgrid.org/members/tale...

Picture Fisk University Professor Steven Damo

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SBGrid Consortium @sbgrid.bsky.social · 02/02/2024

Our Jan member tale puts the spotlight on Bing Chen (Boston Children's Hospital) whose quick pivot to SARS-CoV-2 in 2020 kept the lab in business, & history working with HIV helped to supply techniques for early success & a dedication to uncovering the full fusion story. sbgrid.org/members/tale...?

In this single strand of the trimer spike fusion protein of SARS-CoV-2, the internal fusion peptide (FP in red) forms a hairpin-like wedge that spans almost the entire lipid bilayer, and the transmembrane segment (TM in pink) wraps around the fusion peptide at the last stage of membrane fusion.

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SBGrid Consortium @sbgrid.bsky.social · 02/12/2023

Nov spotlight: Sarah Bowman, who moved through her undergrad degree to a Denver bookstore, eschewing science, until a chemistry class changed her path. Bowman studies metalloproteins at Hauptman-Woodward, heads the HTX Center, & does outreach to encourage others to science sbgrid.org/members/tale...

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