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Sazanov Lab

@sazanovlab.bsky.social
870 followers 683 following 12 posts

Professor, Institute of Science and Technology Austria Visiting Professor, Imperial College London Structure/function of molecular machines and membrane proteins cryoEM Bioenergetics Fellow of Royal Society and EMBO

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Reposted by Sazanov Lab
cryoEM papers @cryoempapers.bsky.social · 19/09/2026
EM3DFold: accurate de novo protein and nucleic acid model building for cryo-EM maps using language model-powered deep learning www.biorxiv.org/content/10.64898/2026.09.16.752067v1 #cryoEM
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Reposted by Sazanov Lab
Institute of Science and Technology Austria (ISTA) @istaresearch.bsky.social · 22/06/2026
Professor Leonid Sazanov and postdoc Ziyu Zhao just published their latest research in @cp-molcell.bsky.social.
📷Leonid Sazanov (left) and Ziyu Zhao (right). © ISTA
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Sazanov Lab @sazanovlab.bsky.social · 21/02/2026
The most snow I have seen on ISTA campus...
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Sazanov Lab @sazanovlab.bsky.social · 14/02/2026
Enjoyed a lot Vienna Science Ball with directors of our "Microbiome" Cluster of Excellence. Great Viennese tradition!
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Reposted by Sazanov Lab
Institute of Science and Technology Austria (ISTA) @istaresearch.bsky.social · 10/10/2025
Join us for the Austrian Cryo-EM Symposium from Nov 11–12 at ISTA! Top speakers, cutting-edge cryo-EM, and a chance to explore Vienna & the ISTA campus. Register now 👉 cryoem-symposium.pages.ist.ac.at/registration/ #cryoEM
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Reposted by Sazanov Lab
Stephen Turner @stephenturner.us · 25/09/2025
Apple is entering the protein folding arena. SimpleFold: Folding Proteins is Simpler than You Think arxiv.org/abs/2509.18480 🧬🖥️🧪 github.com/apple/ml-sim...
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Sazanov Lab @sazanovlab.bsky.social · 18/09/2025
How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint! t.co/962Kj9pt6F
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https://www.biorxiv.org/content/10.1101/2025.09.16.676506v1
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Sazanov Lab @sazanovlab.bsky.social · 20/07/2025
Happy to share new preprint from our collaboration with Peter Nixon group from Imperial College. New insights into Photosystem II assembly/disassembly. t.co/Qac81hZ9kp
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https://www.biorxiv.org/content/10.1101/2025.07.17.665390v1
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Reposted by Sazanov Lab
David Finlay @davidfinlaytcd.bsky.social · 05/01/2025
Authors use an elegant transgenic model to demonstrate that acute oral administration of metformin targets mitochondrial complex I to lower blood glucose. A crucial contribution to the debate about the mechanisms of action of #metformin. #metabolism #glucose doi.org/10.1126/scia...
doi.org
Metformin targets mitochondrial complex I to lower blood glucose levels
Acute oral metformin administration lowers blood glucose levels by targeting mitochondrial complex I.
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Sazanov Lab @sazanovlab.bsky.social · 05/01/2025
Árbol del Tule, Montezuma cypress near Oaxaca in Mexico is amazing. It is the biggest tree in the world by trunk width (14 m diameter). How just a few green needles maintain this tree over 2000 years is a mystery to me.
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Reposted by Sazanov Lab
paulschanda.bsky.social @paulschanda.bsky.social · 18/11/2024
Interested in a doing a PhD at Institute of Science and Technology Austria (ISTA)? Exciting research in phys, chem, structural biology, math, neuro, earth sciences, computer sciences and more... Sign up here for the virtual student open day Nov 20, 2024. phd.pages.ista.ac.at/student-open...
phd.pages.ista.ac.at
Virtual Student Open Day 2024
Each year, the Institute of Science and Technology Austria (ISTA) opens its doors to give prospective PhD and internship candidates an insight into what it is like to study and do research at the inst...
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Sazanov Lab @sazanovlab.bsky.social · 18/11/2024
Hi, I heard there is cryo-EM starter pack here - how do I join? Many thanks!
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