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Sarela Garcia-Santamarina

@sarsarela.bsky.social
352 followers 515 following 8 posts

Professor Deep Microbiome Metabolomics at @Leibniz-HKI #MPS_NOVA Twinning Coordinator #microbiome #microphysiologicalsystems leibniz-hki.de/en/deep-microbiome-m…

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Reposted by Sarela Garcia-Santamarina
Typas Lab @typaslab.bsky.social · 29/04/2026
Check our new preprint by Knopp M. et al.! Human gut microbiomes can impose strong +/- selection for resistant versions of resident opportunistic pathogens. In the case we follow up, selection is driven by altered carbohydrate utilisation that the resistant mutant evolves. doi.org/10.64898/202...
doi.org
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Reposted by Sarela Garcia-Santamarina
Typas Lab @typaslab.bsky.social · 29/04/2026
Great collaboration inside and outside @embl.org @EMBLHeidelberg with @savitski-lab.bsky.social @zimmermannlab.bsky.social @sarsarela.bsky.social y.social @linairmi.bsky.social Gad Frankel @imperialcollegeldn.bsky.social and others #Microbiome #AntibioticResistance #AMR
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Reposted by Sarela Garcia-Santamarina
Guillaume Méric @gmeric.bsky.social · 13/02/2026
Two in a row! Amazing. Here's the list of noteworthy studies I recently stumbled upon (and mostly shared here on bluesky), in the fields of microbiome science, microbial ecology and other stuff. Hope this will be useful to some! mericlab.com/2026/02/14/n...
mericlab.com
Noteworthy from the blue skies — mid-Feb 2026
Two in a row! It’s been a while. I hope this list of interesting recent papers (at least to me!) in the field of microbiome science, microbial ecology and other stuff will be useful to you! A…
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Reposted by Sarela Garcia-Santamarina
AnniZLab: [🦠, 🧬 , ✨] @annizlab.bsky.social · 04/01/2026
Oops - thanks! Right link here www.science.org/doi/10.1126/... #microsky #microbiomesky 🧪🦠
science.org
The specificity and structure of DNA cross-linking by the gut bacterial genotoxin colibactin
Accumulating evidence has connected the chemically unstable, DNA-damaging gut bacterial natural product colibactin to colorectal cancer, including the identification of mutational signatures that are ...
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Sarela Garcia-Santamarina @sarsarela.bsky.social · 12/08/2025
We’re hiring a Postdoc in Gut Microbiome Metabolomics! Help us decode microbial metabolism and its impact on human health @leibniz-hki.de , Jena 🇩🇪 🔗 jobs.hki-jena.de/jobs/Postdoc...
jobs.hki-jena.de
Job opportunity Postdoctoral Researcher (m/f/div) in Gut Microbiome Metabolomics at Leibniz HKI Jobportal
Wissenschaft/Forschung in Jena
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Sarela Garcia-Santamarina @sarsarela.bsky.social · 12/08/2025
We’re hiring a Postdoc on Gut Microbiome–Host Interactions @leibniz-hki.de, Jena 🇩🇪 You'll create organ-on-chip models to study how microbes mediate host responses to xenobiotics jobs.hki-jena.de/jobs/Postdoc...
jobs.hki-jena.de
Job opportunity Postdoctoral Researcher (m/f/div) in Gut Microbiome Host Interactions at Leibniz HKI Jobportal
Wissenschaft/Forschung in Jena
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Sarela Garcia-Santamarina @sarsarela.bsky.social · 12/08/2025
Join our Deep Microbiome Metabolomics team as a Technician! Work with LC/MS & ICP-MS in a cutting-edge microbiome lab @leibniz-hki.de - CTA/chemical lab tech or BSc in chemistry/biochemistry - LC/MS experience - English 🔗 jobs.hki-jena.de/jobs/Technis... #LabJobs #Technician #Metabolomics #LCMS
jobs.hki-jena.de
Stellenangebot Technische*r Assistent*in (m/w/div) bei Leibniz HKI Jobportal
Wissenschaft/Forschung in Jena
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 06/02/2025
🎉 ITQB & #MPS_NOVA Mentoring Program – Strategies for Mentees Workshop 🎉 Today, our mentees gathered at ITQB NOVA for an interactive workshop led by Raquel Oliveira, focusing on the power of mentoring, effective engagement strategies, and self-monitoring. #MentoringProgram #EUTwinning
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 04/02/2025
ITQB NOVA & MPS_NOVA Mentoring Program Launches! The ITQB NOVA Mentoring Program, supported by the #MPS_NOVA Twinning project, is now underway! This edition connects 18 Mentees with experienced Mentors from research, academia, industry, and scientific publishing across Europe. #Mentoring #EuTwinning
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 05/03/2025
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 19/03/2025
💡 Can we reproduce human physiology in a space as small as a chip? 🧐🔬 This was the big question at our #MPS_NOVA stand during the #ITQBNOVA Open Day. There will be more events soon! 👋 #MissionScience #OrganOnChip #OpenDay #ScienceForAll
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 24/03/2025
🎥 A new MPS_NOVA Virtual Seminar is now on YouTube! 🎙 Catarina Brito | Innate Immunocompetent Human 3D Cell Cultures for Preclinical Assessment of Advanced Therapeutics 🎙 Martin Raasch | How to Get Started with Organ-on-Chip lnkd.in/dyBavNwN
lnkd.in
LinkedIn
This link will take you to a page that’s not on LinkedIn
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 09/04/2025
On April 2nd, Pedro Pedrosa, Head of Innovation at ITQB NOVA, visited the Max Delbrück Center for Molecular Medicine in Berlin as part of the MPS_NOVA EU Twinning project. The visit focused on learning from MDC’s Innovation Office to enhance innovation at UNL. #Innovation #KnowledgeExchange
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 16/05/2025
🎉 Exciting Launch: ITQB NOVA MPS_NOVA Labmeeting Series! On March 17th, we kicked off the ITQB NOVA MPS_NOVA Twinning Exploratory Research Projects Labmeetings, a new initiative spotlighting the innovative early-stage research emerging from our vibrant community. #MPS_NOVA #Twinning
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 16/05/2025
🎉 We’re proud to see our hashtag#MPS_NOVA Twinning Conference Attendance Fellowship supporting young researchers at top international events! Luana Macedo presented her work on extracellular vesicles in inter-organ communication at the ISEV 2025 Annual Meeting in Vienna. #ISEV2025 #NMS #Innovation
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 16/05/2025
🎥 A new MPS_NOVA Virtual Seminar is now on YouTube! 🎙️ Raquel Portela (ITQB NOVA) 📢 Modelling Bacterial Pneumonia Infection Dynamics in Lung-on-chip: A Comparative Study of Legionella pneumophila and Staphylococcus aureus. #ITQB #MPS_NOVA #Research #Innovation
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Reposted by Sarela Garcia-Santamarina
Dynamic42 @dynamic42.bsky.social · 01/07/2025
Part 7 of our #MPS2025 interview series highlights Adrian Feile, a PhD student at University Hospital Jena. He explores how DPO-dependent quorum sensing affects Vibrio cholerae biofilm behavior in a 3D intestine-on-chip model --> zurl.co/WJraJ
youtube.com
Minds Behind - Adrian Feile (University Hospital Jena, Germany)
At the MPS World Summit 2025 we had the opportunity to speak to Adrian, a PhD Student at the University Hospital Jena in Germany. He has shown that DPO (3,5-...
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Reposted by Sarela Garcia-Santamarina
Dynamic42 @dynamic42.bsky.social · 26/06/2025
Part 6 of our #MPS2025 series: Meet Daniela Marques, PhD student at @NIMSB_NOVA, Portugal. She develops a microglia crosstalk MPS model of the blood-brain barrier to explore polyphenol metabolites' potential --> zurl.co/Ad5dv
youtube.com
Minds Behind - Daniela Marques (NOVA Institute for Medical Systems Biology, Portugal)
At the MPS World Summit 2025 we had the opportunity to speak to Daniela, PhD Student at the NOVA Institute for Medical Systems Biology in Portugal. She has d...
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Reposted by Sarela Garcia-Santamarina
Dynamic42 @dynamic42.bsky.social · 25/06/2025
Part 5 of our #MPS2025 series highlights Inês Silva, a PhD student at NOVA Institute, Portugal. She developed a microphysiological method to study dopaminergic injury and inflammation in Parkinson’s disease. --> zurl.co/Ow9gg
youtube.com
Minds Behind - Inês Silva (NOVA Institute for Medical Systems Biology, Portugal)
At the MPS World Summit 2025 we had the opportunity to speak to Inês, PhD Student at the NOVA Institute for Medical Systems Biology in Portugal. She has deve...
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
🎥 Dynamic42 GmbH interviewed Sarela García Santamarina, #MPS_NOVA Coordinator, during the recent MPS World Summit 2025. Watch the video to hear her insights on the goals and achievements of the MPS_NOVA Twinning Project.
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
🎉 We are delighted to announce that Maria Beatriz Felgueiras and Quélia Ribeiro from NOVA Medical School have been awarded a Staff Exchange on Methods to Characterize Stem Cells and Organoids at Max Delbrück Center as part of the MPS_NOVA Twinning project!
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
On the 16th and 17th of June, #MPS_NOVA held its fifth training workshop — “Stem Cells, Organoids, and Methods to Characterize Them” — hosted by our partners at Max Delbrück Center for Molecular Medicine.
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
🔬✨ MPS_NOVA at the @Oeiras Valley Science Festival! ✨ On May 23, the MPS_NOVA Twinning Project joined the ITQB NOVA stand at the Oeiras Valley Science Festival in Taguspark — a true “laboratory-outside-the-laboratory” experience!
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
On May 26th we hosted the #MPS_NOVA training workshop on "Strategy in R&I Management", with facilitators from our partner institution, the Max Delbrück Center.
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
📍 Collaboration in Action at ITQB NOVA On May 26th, the MPS_NOVA EU Twinning project had the pleasure of welcoming colleagues from the Innovation and Funding Offices of the Max Delbrück Center, Dr. Nevine Shalaby and Dr. Seda Çöl Arslan, for a highly productive meeting.
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
🌟Join Us for the 4th Webinar of the #MPS_NOVA On July 10th will feature two distinguished speakers at the forefront of advanced therapeutic development using organoids. 👉 Registration here: lnkd.in/dMKs5-Ku 📅 Registration Deadline: July 8th, 2025 (5 pm, WET)
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 07/07/2025
The MPS_NOVA EU Twinning project is pleased to announce the successful completion of our first Staff Exchange “Reprogramming Somatic Cells into Human Induced Pluripotent Stem Cells (hiPSCs)” — hosted by Giovanni Faga group at Human Technopole.
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Reposted by Sarela Garcia-Santamarina
Jacobo de la Cuesta-Zuluaga @jdlcz.bsky.social · 16/07/2025
It's finally out!🎉 We known that the #microbiome confers colonization resistance against #pathogens, we know that some meds 💊 affect gut microbes 🦠 So, do 💊 alter colonization resistance? It turns out that some do! If you wanna know more, check out our latest work www.nature.com/articles/s41...
nature.com
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David Sancho @sancholab.bsky.social · 16/07/2025
💥 A gut microbe metabolite that drives #atherosclerosis? Yes—Imidazole propionate (ImP) triggers vascular inflammation without changing cholesterol. 🧪 We show the pathway—and how to block it. nature.com/articles/s41... #OpenAccess at @Nature @CNIC_CARDIO #CVD #immunosky #cardiosky #microbiomesky
nature.com
Imidazole propionate is a driver and therapeutic target in atherosclerosis - Nature
Imidazole propionate produced by gut microbiota is associated with atherosclerosis in mouse models and in humans, and causes the development of atherosclerosis through activation of the imidazoline-1 ...
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Reposted by Sarela Garcia-Santamarina
Monica Serrano @mokitas.bsky.social · 12/07/2025
endoribonuclease of the YicC-like family delays sporulation via sRNA degradation in Clostridioides difficile url: academic.oup.com/nar/article/...
academic.oup.com
An endoribonuclease of the YicC-like family delays sporulation via sRNA degradation in Clostridioides difficile
Abstract. Clostridioides difficile CD25890 is a YicC-like endoribonuclease involved in regulating sporulation initiation, a process critical for the host–h
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Reposted by Sarela Garcia-Santamarina
Applied Systems Biology @appsysbio.bsky.social · 11/07/2025
Final call for abstracts!! Submit your abstracts for (SBMI 2025) by: 🗓️ July 15, 2025 at 23:59 (CEST Take advantage of Early Bird Registration until: 🗓️ July 31, 2025 at 23:59 (CEST) 🔗 asb-conference.hki-jena.de #SBMI2025 #CallForAbstracts #SystemsBiology
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Reposted by Sarela Garcia-Santamarina
µOrganoLab @microorganolab.bsky.social · 02/04/2025
🔬 Day 2 at the 3R-Network BW Conference! 🚀 Join our team on April 2 for exciting Organ-on-Chip talks in Stuttgart: 🩸 #Metabolism-on-Chip – Studying metabolism with #OrganOnChip 🦠 #Cervix-on-Chip – Immune-responsive model for #HSV-2 research See you soon! 🙌 #3RResearch #MicrophysiologicalSystems
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µOrganoLab @microorganolab.bsky.social · 14/11/2024
Looking forward to tomorrow`s KIC NAMs Meeting of the European Food Safety Authority #EFSA on #MicrophysiologicalSystems. Great to see a broad regulatory interest arising! Peter @plosk.bsky.social will provide a deep dive into the topic introducing #OrganOnChip technology and application scenarios.
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Applied Systems Biology @appsysbio.bsky.social · 15/04/2025
📢 SBMI 2025 Join us at the 8th International Symposium "Systems Biology of Microbial Infection", Sept 18–19, 2025 in Jena Submit your abstract & consider applying for a Tandem-Talk! Info & speakers: asb-conference.hki-jena.de #SystemsBiology #InfectionBiology #BioimageAnalysisTools
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Applied Systems Biology @appsysbio.bsky.social · 10/03/2025
🦠 New Insights into Respiratory Viral Infections 🦠 royalsocietypublishing.org/doi/10.1098/... #Science #Biotechnology #Research #Microbiome #OrganOnChip #LungHealth
royalsocietypublishing.org
Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut–lung axis | Open Biology
The lung microbiome has recently gained attention for potentially affecting respiratory viral infections, including influenza A virus, respiratory syncytial virus (RSV) and SARS-CoV-2. We will discuss...
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Reposted by Sarela Garcia-Santamarina
Applied Systems Biology @appsysbio.bsky.social · 10/03/2025
🦠 Fungal Pathogens & Phagosome Evasion 🦠 New research explores how convergent evolution has shaped fungal effectors to penetrate host phagosomal membranes. www.biorxiv.org/content/10.1... #Microbiology #FungalPathogens #InfectionBiology #Research #PathogenicFungi
biorxiv.org
Convergent evolution of a fungal effector enabling phagosome membrane penetration
The ability of pathogens to evade phagosomal killing is critical for their pathogenicity. Previously, we had identified the HscA effector protein in the clinically important fungal pathogen Aspergillu...
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Reposted by Sarela Garcia-Santamarina
Bork Group at EMBL Heidelberg @borklab.bsky.social · 06/03/2025
We're looking for a postdoc on the Computational Analysis of Environmental #Microbiome Data! embl.wd103.myworkdayjobs.com/en-US/EMBL/j... In the past two years, @embl.org scientists have gathered more than 3000 soil, sediment & water samples from Europe's coastlines within the #TREC expedition (1/2)
embl.wd103.myworkdayjobs.com
Postdoctoral Fellow - Computational Analysis of Environmental Microbiome Data
We are seeking a highly motivated computational biologist to join the research group of Peer Bork within the Molecular Systems Biology Unit as a postdoctoral fellow. This bioinformatics group works on...
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Brochado Lab @brochadolab.bsky.social · 20/02/2025
Brochado and Maier labs in Germany are looking for a PhD student to study horizontal gene transfer in bacteria. ENDAMR Marie Curie doctoral network (endamr.eu) - an amazing opportunity to work with top scientists in the field all around Europe! www.cmfi.uni-tuebingen.de/mariecuriephd
endamr.eu
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 21/01/2025
🌟 Join Us for the 2nd Webinar in the #MPS_NOVA Virtual Seminar Series! 🌟 👉 Read the abstracts and register here: lnkd.in/dCMzrE_c 📅 Registration Deadline: February 4th (5 pm, WET) We can’t wait to see you there! #MPS_NOVA #OrganOnChip #3DCellCultures #EUTwinning
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Sarela Garcia-Santamarina @sarsarela.bsky.social · 21/01/2025
Do not miss this opportunity to hear about innovative host cell models for research and how to get started on them, registration is free
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Typas Lab @typaslab.bsky.social · 23/12/2024
Excited to share our preprint with @savitski_lab led by @tarabartolec.bsky.social, @KMitosch & Clément Potel! We uncovered a mechanism by which the T7 phage broadly counteracts DNA-targeting bacterial defenses by deploying a loose cannon kinase in its genome @embl.org www.biorxiv.org/content/10.1...
biorxiv.org
Pervasive phosphorylation by phage T7 kinase disarms bacterial defenses
Bacteria and bacteriophages are in a constant arms race to develop bacterial defense and phage counter-defense systems. Currently known phage counter-defense systems are specific to (the activity of) ...
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Reposted by Sarela Garcia-Santamarina
MPS_NOVA Twinning Project @mpsnova.bsky.social · 17/12/2024
Last wednesday we had the ITQB NOVA Mentoring Program informative session. The 2025 edition have the support of the MPS_NOVA EU Twinning Project. Sign up as a Mentee : lnkd.in/dH7iUKsY Sign up as a Mentor: lnkd.in/dYaPi62n Deadline: January 12th, 2025 🌟 Join us! #Mentoring #MPS_NOVA
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 20/12/2024
🎄✨ Season’s Greetings from MPS_NOVA! ✨🎄 As 2024 comes to a close, the MPS_NOVA team sends our warmest wishes to all our partners, collaborators, and supporters. A heartfelt thank you to everyone supporting this journey. Wishing you all a warm and joyful holiday season. Happy Holidays from MPS_NOVA
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 04/12/2024
🌟 Join the ITQB NOVA Mentoring Program informative session 🌟 👉 If you’d like to join as a Mentor, please fill out this form: lnkd.in/dYaPi62n 👉 If you’re interested in being a Mentee, fill out this form: lnkd.in/dH7iUKsY #Mentoring #CareerGrowth #ITQBNOVA #ResearchExcellence #MPSNOVA #EUtwinning
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Typas Lab @typaslab.bsky.social · 02/12/2024
Co-supervised by @camille_goemans (@EPFL_en). Many thanks to colleagues inside and outside @embl @elisca.bsky.social (@ETH_en), @AskarbekOrakov, @TheRealFloHu, @ValloVarik, @michielslab.bsky.social (@vibmicrobes.bsky.social /@KU_Leuven), @borklab.bsky.social and @cossartpascale.
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Typas Lab @typaslab.bsky.social · 02/12/2024
Excited to share our study led by @SakenovaNazgul! We used chemical genetics to identify and understand cross-resistance & collateral-sensitivity (CS) between antibiotics and reduced AMR development with CS drug pairs @embl.org with @camille_goemans @EPFL_en www.nature.com/articles/s41...
nature.com
Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics - Nature Microbiology
Resistance to one antibiotic can make bacteria resistant or sensitive to another antibiotic, opening paths for combinatorial treatments. This study presents an approach to systematically discover and ...
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EMBL @embl.org · 02/12/2024
(1/3) Antibiotic resistance is costing human lives. 🦠 A study from EMBL's Typas group proposed a framework to identify antibiotic pairs that make bacteria resistant to one antibiotic but sensitive to other – this can help design new treatments and delay resistance. 🧬🧪 www.nature.com/articles/s41...
Credit: Daniela Velasco Lozano/EMBL
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 29/11/2024
🌟 Join us for the First #MPS_NOVA Virtual Seminar🌟 📣Microfluidics and the Future of Organ-on-Chip: Driving Innovation Through Standardization with Vania Silverio on December 5th at 2 pm (WET). 👉 Registrer here: lnkd.in/daRMgiZk (free, but mandatory) 📅 Registration Deadline: 2 December 2024
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MPS_NOVA Twinning Project @mpsnova.bsky.social · 28/11/2024
In November, #MPS_NOVA held its kick-off meeting at ITQB NOVA, bringing together researchers & staff from @itqbnova.bsky.social, @nova_medschool, @uniklinik_jena, @BIMSB_MDC, @humantechnopole.bsky.social #Organoids, #iPSC, #Stemcells, #microphysiologicalsystems, #NAMs
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Sarela Garcia-Santamarina @sarsarela.bsky.social · 25/11/2024
www.linkedin.com/posts/mps-no...
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