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SAND Lab

@sandlab.bsky.social
29 followers 29 following 7 posts

We are the Synaptic and Network Development (SAND) Group. Our research focuses on understanding microscale functional neuronal networks in development and neurodevelopmental disorders.

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SAND Lab @sandlab.bsky.social · 28/05/2026
Congratulations to George, Andras, @lakatoslab.bsky.social and collaborators for the publication of the human motor axis in dish! As a neurologist, it was amazing to see the corticospinal tract in vitro and how it can reveal new strategies for axon regrowth after injury. www.cell.com/cell-reports...
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SAND Lab @sandlab.bsky.social · 20/12/2025
We are excited to share our new pre-print "Mecp2 deficiency impairs microscale cortical network topology and dynamics in a Rett syndrome mouse model" on bioRxiv! www.biorxiv.org/content/10.6...
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SAND Lab @sandlab.bsky.social · 02/12/2024
Hurrah! The bioRxiv preprint introducing MEA-NAP is now linked to the Cell Reports Methods publication! #MEA-NAP
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SAND Lab @sandlab.bsky.social · 02/12/2024
Jeremi spotted this cool paper studying Parkinson's disease in midbrain-striatum organoids that assessed the degree of functional connectivity, between different regions of their assembloid on the microelectrode array, using MEA-NAP! www.nature.com/articles/s42...
nature.com
Modeling early phenotypes of Parkinson’s disease by age-induced midbrain-striatum assembloids - Communications Biology
Generation of a midbrain-striatum assembloid with progerin overexpression as an in vitro model of possessing aging and senescence characteristics for studying Parkinson’s disease.
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SAND Lab @sandlab.bsky.social · 21/11/2024
Congrats to Yiwei Gong on posting on arXiv her PhD work featuring our new network dynamics method for MEA data! arxiv.org/abs/2411.04229 #neuroscience
arxiv.org
Detecting State Changes in Functional Neuronal Connectivity using Factorial Switching Linear Dynamical Systems
A key question in brain sciences is how to identify time-evolving functional connectivity, such as that obtained from recordings of neuronal activity over time. We wish to explain the observed phenome...
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SAND Lab @sandlab.bsky.social · 20/11/2024
Our MEA-NAP video abstract appears on the Cell Press YouTube channel with an #elephant-showering!! youtu.be/RJuvSDivApQ?...
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SAND Lab @sandlab.bsky.social · 20/11/2024
We are also excited about more to come!!
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Reposted by SAND Lab
Andras Lakatos @LakatosLab @lakatoslab.bsky.social · 18/11/2024
3D human brain organoid neuronal network analysis strategies: an exciting collaborative work led by Susanna Mierau - and more to come: www.cell.com/cell-reports...
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