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Sameer Jauhar @sameerjauhar.bsky.social · 15/08/2025

So what? Fair points- limbic selectivity for mood psychoses mapping onto therapeutic agents, and transdiagnostic approaches for positive symptoms? I will take that, though happy for critique!

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Sameer Jauhar @sameerjauhar.bsky.social · 15/08/2025

DA lowers in ppl w psychosis and MDE than ppl w mania (esp Mesolimbic system) DA correlated w positive sx, across diagnoses (esp associative striatum) Take home? Symptoms track biology as opposed to diagnoses, though differences still exist across disorders.

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Sameer Jauhar @sameerjauhar.bsky.social · 15/08/2025

Answers-look at the Figures, see what you think

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Sameer Jauhar @sameerjauhar.bsky.social · 15/08/2025

We used PET to examine dopamine synthesis in ppl w psychosis and mood disorders. 2 questions: i) Is DA reduced in ppl w psychosis+ major depressive episode? ii) Is there a relationship between DA and positive psychotic sx (delusions and hallucinations) across affective psychoses?

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Sameer Jauhar @sameerjauhar.bsky.social · 22/03/2025

Looks like I may have some teaching to do in my new job at Imperial. Thanks, Dr Moncrieff!

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Sameer Jauhar @sameerjauhar.bsky.social · 19/03/2025

What he would wish if he had a psychotic illness, and.....favourite pizza topping!

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Sameer Jauhar @sameerjauhar.bsky.social · 19/03/2025

5:00 mins- “ I naively thought all novels were fiction” “science is failure” Just treat patients for a week and make a note every time you feel anxious, there is a research question there....."

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Sameer Jauhar @sameerjauhar.bsky.social · 19/03/2025

Great fun interviewing John Kane, who came out with some beautiful insights media.kcl.ac.uk/media/Rollin...

media.kcl.ac.uk

Rolling Thunder - An evening with Professor John Kane (subtitled) - King’s College London

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