iiinova — where your digital self keeps evolving

Reposted by Saket Choudhary

Maria Antonietta Tosches @matosches.bsky.social · 27/07/2026

Excited to share a new preprint from the lab, by @andrewmatheson.bsky.social and team, where we dive into the superpower of newts: plasticity! www.biorxiv.org/content/10.6... Like many good projects, this started with a serendipitous observation... 🧵1/5

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Reposted by Saket Choudhary

Maria Antonietta Tosches @matosches.bsky.social · 29/06/2026

Better late than never... an update on the recent work from the lab. First of all, the Foundation: @astridd93.bsky.social phenomenal paper on the evolution of layering in the cerebral cortex 🧵1/7 www.biorxiv.org/content/10.1...

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Saket Choudhary @saketkc.bsky.social · 29/12/2025

Lovely! Let me know how it goes and if you have any suggestions!

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Saket Choudhary @saketkc.bsky.social · 29/12/2025

Indeed! Here's bwt: saket-choudhary.me/bwt. Thanks for catching it!

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Saket Choudhary @saketkc.bsky.social · 29/12/2025

1. A tool to visualise how local alignment differs from global alignment side by side: saket-choudhary.me/alignmyseq/ 2. A Burrows-Wheeler Transform and inverter: saket-choudhary.me/alignmyseq/ All slides and materials are available here: saket-choudhary.me/DH607/syllab...

saket-choudhary.me

Syllabus – DH607 - Autumn 2025

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Saket Choudhary @saketkc.bsky.social · 29/12/2025

The past semester's run of DH607 - Introduction to Computational Multi-Omics at KCDH, leveraged "vibe coding" to create two tools I've always wanted:

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Saket Choudhary @saketkc.bsky.social · 14/11/2025

Registrations closing soon for our QSCB workshop (Dec 15th-16th)! Details: saketlab.in/qscb-workshop/

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Saket Choudhary @saketkc.bsky.social · 30/04/2025

For an outsider(me), the field seems full of cool ideas, methods and promise! 3/3

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Saket Choudhary @saketkc.bsky.social · 30/04/2025

The course starts with a short history of the field, jumps into methylation and RNA clocks, and discusses how a simple PCA boosts accuracy. Finally, we discuss single-cell methylation and RNA clocks. JC-style Slides here (we did a lot of chalk talk): saket-choudhary.me/DH603/syllab... 2/3

saket-choudhary.me

Syllabus – DH603: Computational Multi-omics of Ageing

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Saket Choudhary @saketkc.bsky.social · 30/04/2025

Interested in the omics of ageing? We taught a short course this semester. Focus was on learning the nuts and bolts of the various ageing clocks that exist out there and how they work (or don't). 1/3

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Saket Choudhary @saketkc.bsky.social · 12/04/2025

The first part of the semester-long course at KCDH/IIT Bombay focuses on teaching the statistical techniques required to analyse public health data. All course material (slides+videos) here: saket-choudhary.me/DH302 (2/2)

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Saket Choudhary @saketkc.bsky.social · 12/04/2025

Did death patterns change in India pre- and post-COVID-19? What (likely) explains the seasonality of births in India? Does wealth (not?) drive happiness? These are some questions we tried to answer in the Spring '25 run of DH302-Introduction to Public Health Informatics (1/2)

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Saket Choudhary @saketkc.bsky.social · 07/04/2025

Even more interesting is to see the change in the month of highest births. For example: Norway (from April up to 2000s to July there after):

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Saket Choudhary @saketkc.bsky.social · 07/04/2025

Fantastic study! Interestingly most births in India are in the second half --> and are conceived during the winters. Temperature and percentage of conceptions are anti-correlated.

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Saket Choudhary @saketkc.bsky.social · 06/04/2025

Thanks for bumping this up! This came out of a simple need - I was clueless as to why something similar didn't exist then!

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Reposted by Saket Choudhary

Jacob Schreiber @jmschreiber91.bsky.social · 14/03/2025

As a field, I believe we must move towards COMIC SANS logo plots immediately. nbviewer.org/github/saket...

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