iiinova — where your digital self keeps evolving

Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 29/06/2026

🚨 New #ICUrehab Meta-analysis synthesising the measurement properties of the #CPAx shows strong validity & reliability with acceptable measurement error, minimal floor/ceiling effects supporting its use across recovery doi.org/10.1016/j.jp... @michelle-icu.bsky.social @camilocaceresp.bsky.social

GRADE Table
excellent inter-rater reliability (pooled ICC 0.99, 95% CI 0.98 to 1.00, six studies, high-quality evidence), intra-rater reliability (ICC 0.95, 95% CI 0.82 to 0.97, one study, low-quality evidence) and acceptable standard error of measurement (pooled SEM 1.36, five studies) corresponding to a smallest detectable change of 3.76 (sufficient rating, high-quality evidence). Construct validity was supported with 26 out of 34 predefined hypotheses accepted (76%, sufficient, 10 studies, moderate-quality evidence) and responsiveness with five out of six predefined hypotheses accepted (83%, sufficient, five studies, very low-quality evidence).

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 26/03/2026

Our PEAiCE study (845 respondents, 33 countries) maps #ICU #physiotherapy across Europe: Wide variability, but the good news? The majority is treating mechanically ventilated patients for #ICUrehab and respiratory management 💪🫁🧠 www.sciencedirect.com/science/arti... @agilewko.bsky.social

Fig. 2. Number of respondents per country. Darker shades (more answers) for Western than Eastern Europe.

Physiotherapists treating invasively mechanically ventilated patients (n = 740): 84% are treating them for both early rehab and respiratory management

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 27/10/2025

#ESICM #LIVES2025 🩺 Opening Ceremony 📝 Take Home Messages: 💆🏼‍♀️"We need to take care of ourselves to care for others." 👩‍🦽Person with lived experience: "The patient is not just a problem to be solved, do not forget the person!"

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 30/05/2025

It was an honour to present our results of the PEAiCE study at #WorldPhysio2025 See below for poster 👇 Interesting, physios rarely screen for delirium despite the impact of #ICUrehab on the condition. More work to do💪

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 06/05/2025

The 9th Asia Pacific conference on Weaning and Early Mobilization for Critically Ill Patient will be in Tokyo just after #WorldPhysio25 - see link for the exciting program: pub.idisk-just.com/fview/5eWW7o...

Flyer with the title and the dates May 31 and June 1, hyprid format possible

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 11/12/2024

N=60'055 (!) included in analysis Baseline difference of COVID-19 5% in control vs. 12% in treatment groups Both groups received many alerts 🤔 #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 11/12/2024

Importantly, the alert is a tool initiating detailed assessment 🩺🥼 45 wards were randomised, concealed until one month before start over 10 periods (from period 3: impacted by COVID-19) #CCRdownunder #CCRdownunder24

Trial design and impact of COVID-19 in orange

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 11/12/2024

Lastly, the SCREEN trial 🏥 electronic early recognition of sepsis in hospitalised patients 📝 stepped-wedged RCT 🎯 90-day in-hospital mortality ⚠️ sepsis alert based on GCS, RR, SBP #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 11/12/2024

Methodology was quite complicated, further explanation on inferiority during editorial 👍 #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 11/12/2024

Results & conclusions 👇 HFNC was noninferior to NIV Adverse events were very similar btw groups #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 11/12/2024

RENOVATE trial is coming up now 🩻 HFNC vs. NIV in ARF 📝 multicentre, adaptive RCT in Brazil 🎯 endotracheal intubation or death at day 7 I like that they included a step-down procedure along with initiation protocol 👌 #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 10/12/2024

Half of pts were intubated, 1/3 went to the ICU, 22% received surgery No difference in primary outcome, tendency to more death in restricted O2 #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 10/12/2024

Summary and link to publication 👇 www.nejm.org/doi/full/10.... #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 10/12/2024

SAHaRA trial comes up 🏥Subarachnoid hemorrhage 50% have anaemia (associated with poorer outcomes) 🩸liberal vs. restrictive red blood transfusion 📝 RCT 🎯 modified Rankin Scale + FIM, 5EuroQOL at 12mth #CCRdownunder #CCRdownunder24

Overview of the condition from short to long-term outcomes

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 10/12/2024

Editorial Applaus for a trial focusing on the survivorship 👌 Mechanisms under study easily explained 🧪

Outcomes after sepsis, often trials focus on the start but not the outcomes

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 10/12/2024

N=214 randomised 🎯 no effects for time to first infection-reated rehospitalisation #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 10/12/2024

Next up VACRiSS trial Can a vaccine (PCV13) reverse immune impairments in sepsis survivors? #CCRdownunder #CCRdownunder24

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 10/12/2024

Next VACRiSS trial Rationale & background: Sepsis survivors suffer from poor health, immune impairments common. Can a vaccine (PCV13) reverse this? Particularly, t-cell function? #CCRdownunder24 #CCRdownunder

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 09/12/2024

N=2762 🎯Effect for PCT, but not for CRP 🎯No diff on mortality at 90 days #CCRdownunder

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 09/12/2024

First trial: ADAPT sepsis 🏥Hospitalised adults with suspected sepsis 💊antibiotic disconinuation 📃3-arm RCT 🎯total duration of antibiotics & mortality #CCRdownunder

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 09/12/2024

I'm here #CCRdownunder what a beautiful start to the day with a welcome to country @criticalcarereviews.com

2:10 countdown, classical musicians playing

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 11/11/2024

The best about protected research time is the Work-Life-Balance; for the first time, I have time for both research and to explore this beautiful country! #AcademicChatter #Postdoc #MondayMotivation

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Sabrina Eggmann, PhD @sabrinaeggmann.bsky.social · 04/02/2024

We need to talk about adverse events #AE during physical rehabilitation #ICUrehab in critical care trials Challenges: 📌definition of AEs 📌harm from immobility vs mobilisation 📌reactions to exercise 📌underdosing, exhaution & muscle inexcitabily 📎 www.thelancet.com/journals/ecl...

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