iiinova — where your digital self keeps evolving

Simon Kohl @saakohl.bsky.social · 11/08/2025

It's been great to talk to Tom Mackenzie of Bloomberg News about the launch of our protein design model and platform this morning!

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Reposted by Simon Kohl

Latent Labs @latentlabs.bsky.social · 25/07/2025

🧬Latent-X is our first frontier model for protein design. For mini-binders, our AI model achieved picomolar binding affinities — the strongest reported vs prior methods in head-to-head lab validation. Explore our best binders here: platform.latentlabs.com More details on the breakthrough in this🧵

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Simon Kohl @saakohl.bsky.social · 22/07/2025

Starting with macrocycles and mini-binders. Can't wait for your feedback! More to come! For requests beyond current platform capabilities: partnerships@latentlabs.com.

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Simon Kohl @saakohl.bsky.social · 22/07/2025

We’re making Latent-X available with a free tier for commercial and academic users alike. We want to get cutting-edge AI into the hands of scientists at big pharma and small labs without needing AI teams or infrastructure.

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Simon Kohl @saakohl.bsky.social · 22/07/2025

What excites me most: getting this into the hands of scientists through our no-code platform. Replicates our validated workflows, no AI background required. And it’s fast — up to 10x faster than prior methods!

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Simon Kohl @saakohl.bsky.social · 22/07/2025

Latent-X generates novel binders from scratch, solving the geometric puzzle of binding at the all-atom level while obeying biochemical rules nature follows. I'm still mesmerized watching the model generate successful binders directly at the atom level — hydrogen bonds included!

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Simon Kohl @saakohl.bsky.social · 22/07/2025

Latent-X achieved breakthrough lab results: Picomolar binding affinities, directly outperforming prior methods in head-to-head validation. Leading experimental hit rates: * 91-100% for macrocycles * 10-64% for mini-binders Testing 30-100 designs per target vs millions traditionally.

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Simon Kohl @saakohl.bsky.social · 22/07/2025

Introducing Latent-X — our all-atom frontier AI model for protein binder design. State-of-the-art lab performance, widely accessible via the Latent Labs Platform. Free tier: platform.latentlabs.com Blog: latentlabs.com/latent-x/ Technical report: tinyurl.com/latent-X

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Reposted by Simon Kohl

Latent Labs @latentlabs.bsky.social · 22/07/2025

5 months from funding to shipping our first frontier model. Latent-X achieves state-of-the-art hit rates for macrocycles and mini-binders, with picomolar binding affinities — a breakthrough in de novo protein binder design. Available now on our no-code platform!

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Simon Kohl @saakohl.bsky.social · 14/02/2025

Thank you, Jason! It has been awesome to work with you when starting the protein design team at DM and fantastic to see all your work since then :)

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Simon Kohl @saakohl.bsky.social · 13/02/2025

Apply to access our tools or join the team www.latentlabs.com

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Simon Kohl @saakohl.bsky.social · 13/02/2025

It is clear protein design has the potential to transform medicine and scientific discovery. I believe Latent Labs will be the team to fully realize its potential. It’s a vast field and there’s so much still to do. Let’s go!

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Simon Kohl @saakohl.bsky.social · 13/02/2025

I loved my time at DeepMind working on AlphaFold2 and to be there in Stockholm to watch Demis Hassabis and John Jumper accept the Nobel Prize was incredible.

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Simon Kohl @saakohl.bsky.social · 13/02/2025

We’ve built an exceptional founding team – and are hiring in London and San Francisco! Come join the likes of Alex Bridgland (AlphaFold 1, 2 & 3), Annette Obika-Mbatha (multiple DeepMind programs), Dave Yuan (Mammoth Bio) and amazing people from Microsoft, Google, Altos Labs, Stability AI and more.

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Simon Kohl @saakohl.bsky.social · 13/02/2025

Our Angels include Google Chief Scientist @jeffdean.bsky.social, Transformer architecture co-inventor and Cohere founder @aidangomez.bsky.social, and ElevenLabs founder Mati Staniszewski.

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Simon Kohl @saakohl.bsky.social · 13/02/2025

The funding includes our Series A co-led by Radical Ventures and Sofinnova Partners, with existing investors Pillar VC, Kindred Capital and 8VC participating alongside new investors Isomer Capital and Flying Fish.

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Simon Kohl @saakohl.bsky.social · 13/02/2025

Every biotech or pharma company searching for the best therapeutic molecules understands the role AI can play - but not all are in a position to develop their own advanced models. That’s where @latentlabs.bsky.social comes in.

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Simon Kohl @saakohl.bsky.social · 13/02/2025

Latent Labs comes out of stealth today with $50M funding. Our goal? To push the frontiers of generative biology, giving partners instant access to tools capable of accelerating drug design

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