Sign in

Simon Kohl

@saakohl.bsky.social
135 followers 24 following 18 posts

Founder & CEO at Latent Labs

PostsRepliesMedia
Simon Kohl @saakohl.bsky.social · 11/08/2025
It's been great to talk to Tom Mackenzie of Bloomberg News about the launch of our protein design model and platform this morning!
110
Simon Kohl @saakohl.bsky.social · 22/07/2025
Starting with macrocycles and mini-binders. Can't wait for your feedback! More to come! For requests beyond current platform capabilities: partnerships@latentlabs.com.
000
Simon Kohl @saakohl.bsky.social · 22/07/2025
We’re making Latent-X available with a free tier for commercial and academic users alike. We want to get cutting-edge AI into the hands of scientists at big pharma and small labs without needing AI teams or infrastructure.
120
Simon Kohl @saakohl.bsky.social · 22/07/2025
What excites me most: getting this into the hands of scientists through our no-code platform. Replicates our validated workflows, no AI background required. And it’s fast — up to 10x faster than prior methods!
110
Simon Kohl @saakohl.bsky.social · 22/07/2025
Latent-X generates novel binders from scratch, solving the geometric puzzle of binding at the all-atom level while obeying biochemical rules nature follows. I'm still mesmerized watching the model generate successful binders directly at the atom level — hydrogen bonds included!
110
Simon Kohl @saakohl.bsky.social · 22/07/2025
Latent-X achieved breakthrough lab results: Picomolar binding affinities, directly outperforming prior methods in head-to-head validation. Leading experimental hit rates: * 91-100% for macrocycles * 10-64% for mini-binders Testing 30-100 designs per target vs millions traditionally.
100
Simon Kohl @saakohl.bsky.social · 22/07/2025
Introducing Latent-X — our all-atom frontier AI model for protein binder design. State-of-the-art lab performance, widely accessible via the Latent Labs Platform. Free tier: platform.latentlabs.com Blog: latentlabs.com/latent-x/ Technical report: tinyurl.com/latent-X
2134
Simon Kohl @saakohl.bsky.social · 13/02/2025
Apply to access our tools or join the team www.latentlabs.com
021
Simon Kohl @saakohl.bsky.social · 13/02/2025
Latent Labs comes out of stealth today with $50M funding. Our goal? To push the frontiers of generative biology, giving partners instant access to tools capable of accelerating drug design
24013