iiinova — where your digital self keeps evolving

Rosetta Commons @rosettacommons.bsky.social · 17h

Researchers from @aiproteins.com introduce a streamlined workflow that could reshape how labs produce proteins at scale. The method tackles key bottlenecks across the entire protein production pipeline and is designed to be fully compatible with automation. Read more: zurl.co/kAHMW

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Rosetta Commons @rosettacommons.bsky.social · 01/10/2026

Recent progress in computational protein design is rapidly transforming the field of biomolecular research. Key highlights include: 🔹 Novel methods combining deep learning + physical modeling 🔹 Custom data collection & automated pipelines 🔹 Emerging applications in functional protein engineering

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Rosetta Commons @rosettacommons.bsky.social · 01/10/2026

Join us for Winter RosettaCon 2027, presented with Keystone Symposia, for the Computational Design and Modeling of Biomolecules meeting on Mar 29 - Apr 1, 2027 in Santa Fe, NM, and connect with leading researchers across biotech, AI, and structural biology. rosettacommons.org/events/wrc/

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Rosetta Commons @rosettacommons.bsky.social · 30/09/2026

Day 2 of European RosettaCon 2026, our invited speakers will dive into their research spanning: Microfluids, molecules & nanopores AI & language models for protein design Neurodegenerative disease biomarkers & vaccine antigen design Register today to attend virtually: europeanrosettacon.org

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Rosetta Commons @rosettacommons.bsky.social · 29/09/2026

Looking to streamline your ML protein design workflows? 🧬✨ Rosetta Commons just dropped a new hands-on tutorial: "How to Build a Model with AtomWorks." You'll explore essential API functions, construct a custom dataset, and train a Graph Neural Network (GNN) model from scratch. zurl.co/znS8E

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Rosetta Commons @rosettacommons.bsky.social · 28/09/2026

Meet Terra! Terra’s lab is interested in the physical principles underlying biological function. They integrate an interdisciplinary approach to design novel molecules that address environmental and medical challenges. Learn more about Terra in our September 2026 newsletter. zurl.co/w5cZk

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Rosetta Commons @rosettacommons.bsky.social · 25/09/2026

Summer RosettaCon 2026 at the University of Washington was a week to remember. We spent August 3–7 jammed-packed with fascinating science, meaningful networking, and unforgettable memories— from trail hikes with friends to unwinding next to fossils after long days. Read the recap here: zurl.co/0UVrv

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Rosetta Commons @rosettacommons.bsky.social · 23/09/2026

Part 1: Code School | Coding, Collaboration, and Camaraderie rosettacommons.org/2026/09/21/c... Part 2: Host Labs & RosettaCon | A Summer of Science rosettacommons.org/2026/09/21/a... Part 3: Research Projects | Highlighting Exciting First Steps in Research rosettacommons.org/2026/09/21/r...

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Rosetta Commons @rosettacommons.bsky.social · 23/09/2026

Starting with a week-long Code School, followed by eight weeks conducting research, and ending by presenting at Summer RosettaCon, the Rosetta Commons REU program gives the next generation of biomolecular modeling and design researchers a hands-on head start. Apply: rosettacommons.org/education/reu

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Rosetta Commons @rosettacommons.bsky.social · 18/09/2026

As part of the Tech Tea Time series, Ethan Holz, a software engineer for the Open Molecular Software Foundation (OMSF), led a discussion on the current state of building and using agents for computational workflows, covering tools like Claude Code, Pi, and Codex. 🎥 Watch here: zurl.co/PhLrM

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Rosetta Commons @rosettacommons.bsky.social · 17/09/2026

Day 1 at European RosettaCon 2026, our invited speakers are taking the stage to share their research in: Computational & functional protein design Evolutionary design of ancient proteins Molecular dynamics & binder design Virtual registration is open! Register now: europeanrosettacon.org

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Rosetta Commons @rosettacommons.bsky.social · 16/09/2026

Researchers developed a two-phase approach combining Rosetta-based motif grafting with deep-learning tools, including RFdiffusion, ProteinMPNN, and AlphaFold2 to generate high-affinity binders that successfully targeted bone regeneration. Read more: rosettacommons.org/2026/09/16/t...

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Rosetta Commons @rosettacommons.bsky.social · 14/09/2026

Introducing the free monthly virtual series - Rosetta Commons Toolkit: A Practical Webinar Series for Biomolecular Modeling and Design! Our debut session features Henry Dieckhaus from UNC Chapel Hill taking a deep dive into ThermoMPNN. Every skill level welcome! rosettacommons.org/rctoolkit/

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Rosetta Commons @rosettacommons.bsky.social · 10/09/2026

In the latest Protein Design Workflows Group presentation, Gianluca Quargnali (University of Zurich) introduces BioPipelines—an open-source Python framework that lets you define complex, multi-step protein and ligand design workflows in just a few lines of code. 🎥 Watch here: zurl.co/o5WWw

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Rosetta Commons @rosettacommons.bsky.social · 09/09/2026

Researchers at Outpace Bio and the University of Washington present OUTLAST Regulators, de novo designed, compact protein modules that simultaneously modulate multiple target proteins to reprogram cellular pathways and sustain T cell functional persistence. Read more: zurl.co/Kkw2T

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Rosetta Commons @rosettacommons.bsky.social · 07/09/2026

OpenBind announced the release of the OpenBind-0 model, a fully open-source co-folding model built on OpenFold3, trained on Protein Data Bank (PDB) data, and optimized for predicting protein–small-molecule complexes. Read more: zurl.co/W7FCy

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Rosetta Commons @rosettacommons.bsky.social · 03/09/2026

Design2Data (D2D) is a nationally networked Course-based Undergraduate Research Experience (CURE) program. They are welcoming new members for the 2026–2027 academic year and invite you to consider joining them. Apply today: zurl.co/6Hqyw

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Rosetta Commons @rosettacommons.bsky.social · 02/09/2026

The scientific program for European RosettaCon 2026 has officially arrived! 🧪 Explore the full line-up of speakers sharing their latest research across the three days, including 3 keynotes, 7 presentation sessions, and 3 poster sessions. Virtual registration is now open: europeanrosettacon.org

An image of the Padrãos does Descobrimentos (Monument to the Discoveries) sculpture in front of purple and orange lit clouds during sunset. The portion of the sculpture shown is primarily white colored and shows one man dressed in clothes from the late 15th century with the man in the front holding a model of a sailing ship. The text on the image says, “European RosettaCon, Lisbon, Portugal, Scientific Program Now Posted, 28th to 30th of October, 2026, Rectorate of the NOVA university of Lisbon, Virtual Registration Open, europeanrosettacon.org” It has the NOVA, SPBf, Rosetta Commons, and Rosetta Design Group logos at the bottom of the image.

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Rosetta Commons @rosettacommons.bsky.social · 01/09/2026

In a recent paper by Zach Drake and other members from the Lindert Lab, a new set of tutorials and updated PyRosetta implementations make using integrated structural mass spectrometry pipelines accessible to non-expert users. Read more: zurl.co/dKOro

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Rosetta Commons @rosettacommons.bsky.social · 31/08/2026

Meet Kevin! Kevin’s lab is currently trying to uncover the identities of protein assembly components, determine their 3D structure, and modulate their activity. Learn more about Kevin in our August 2026 newsletter. rosettacommons.org/community/ne...

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Rosetta Commons @rosettacommons.bsky.social · 26/08/2026

Prof. Tanja Kortemme is an innovator in computational protein design. Her research focuses on physical interactions at all scales, from atoms and molecules to complex biological systems. Hear her group's latest breakthroughs at European RosettaCon 2026! Virtual registration is open. zurl.co/h9iB1

An announcement of Tanja Kortemme as a keynote speaker for European RosettaCon. It notes she is from University of California, San Francisco and her talk will be titled Programming dynamic proteins. At the bottom are the logos for NOVA University, SPBf, Rosetta Commons, and Rosetta Design Group. The background has a purple colored sky at the top and then an off-white background for most of the image with some purple spirals on the sides.

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Rosetta Commons @rosettacommons.bsky.social · 20/08/2026

Meet the 2026–2027 Rosetta Commons Postbac Trainees! 🧬 Adaym, Ainur, Cailyx, Daniel, and Linda started their journey at Johns Hopkins studying ML & protein design. Now, they’re diving into research across the King, Rocklin, Das, Khare, and Hosseinzadeh labs! rosettacommons.org/education/ra...

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Rosetta Commons @rosettacommons.bsky.social · 18/08/2026

🧬 Want to stay updated on protein science? Check out the @bpdmc.org monthly presentation series! Recent topics: • Computational antibody design • Energy-based models & structure • De novo small-molecule induced changes Learn more, watch past presentations, and join the community at bpdmc.org.

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Rosetta Commons @rosettacommons.bsky.social · 14/08/2026

Calling all job seekers! Following an engaging Summer #RosettaCon, our Jobs Board has been fully refreshed. We currently have 30+ open positions spanning both academia and industry, with opportunities available across career stages. Explore the open roles and apply today: rosettacommons.org/jobs/

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Rosetta Commons @rosettacommons.bsky.social · 13/08/2026

A companion written tutorial is also available here: rosettacommons.github.io/foundry/mode...

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Rosetta Commons @rosettacommons.bsky.social · 13/08/2026

RFDiffusion3 simple motif scaffolding tutorials are here! Follow along with this RFDiffusion3 video tutorial to learn how to design an entirely new scaffold to preserve a catalytic structural motif extracted from a known protein structure. www.youtube.com/watch?v=bFSW...

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Rosetta Commons @rosettacommons.bsky.social · 12/08/2026

Celebrating incredible service at Summer #RosettaCon! Congrats to this year’s Rosetta Commons Service Award winners: Jeffrey Gray — Over a decade of visionary leadership & founding our REU & postbac programs. Austin Seamann — Extraordinary dedication to education & producing Rosetta/ML tutorials.

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Rosetta Commons @rosettacommons.bsky.social · 11/08/2026

Congratulations to our Summer #RosettaCon 2026 poster award winners: Hayden Stegall (Rice), Iris Zheng (JHU), Russell McLoughlin (UO), Gangeun Park (KAIST), Adrianne McCormick and Steven Engelbretson (UW). Thank you to everyone who shared their work, we learned so much from each of you!

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Rosetta Commons @rosettacommons.bsky.social · 10/08/2026

Thank you to everyone who joined us at Summer #RosettaCon 2026—in-person and virtually! You make this community a place where groundbreaking science and celebrating each other go hand in hand. What was your favorite talk, poster, or experience from this year’s event? Share below!

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

At Summer #RosettaCon 2026, our invited speakers, Terra Sztain, Cameron Glasscock, Gyu Rie Lee, and Martin Pačesa, brought incredible research to the stage with fantastic presentations. Thank you to AstraZeneca for sponsoring the conference and helping us amplify scientific leaders.

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

Hands-on tutorials at Summer #RosettaCon 2026 gave attendees the chance to level up their skills—covering everything from AI agents and the Data Bazaar to essential documentation best practices. Thank you to Xaira Therapeutics for supporting the conference and these moments.

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

At Summer #RosettaCon 2026, meals gave trainees and established researchers a unique space to connect—sparking new collaborations, sharing career advice, and exchanging fresh ideas. Thank you to RA Capital for supporting the conference and helping fuel these meaningful connections for our community.

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

Deep dives and big next steps! From focused topic chats to career panels on academia, industry, next steps, and career left turns, Summer #RosettaCon 2026 was all about supporting researchers at every stage. Thank you to Achira for helping support these impactful opportunities!

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

Summer #RosettaCon 2026 brought incredible insights to the stage each evening with keynotes from Alex Rives (Biohub), Jeff Way (Harvard University), and Alanna Schepartz (UC Berkeley). Thank you to Lila for supporting the conference and making these memorable presentations possible.

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

The poster sessions are always a highlight of Summer #RosettaCon! They give researchers a dedicated space to connect one-on-one, dig into the details, and share findings. Thank you to Profluent for sponsoring the conference and creating these vital moments of connection for our community.

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

Thank you to Absci for enriching the scientific discussions at Summer #RosettaCon 2026! Key topics covered included generative AI, therapeutic applications, and vaccines. Events like this showcase the power of community collaboration as we push the boundaries of computational biology together.

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Rosetta Commons @rosettacommons.bsky.social · 07/08/2026

Thank you to Manifold Bio for supporting Summer RosettaCon 2026. Researchers shared their latest results in topics including de novo antibody design, high-throughput measurements, and protein dynamics sharing innovative ideas with each other as they look for solutions to real world challenges.

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Rosetta Commons @rosettacommons.bsky.social · 06/08/2026

What an exciting week at Summer RosettaCon 2026! Scientific discussions kicked off with this Keynote Panel featuring Sergey Ovchinnikov, Gabe Rocklin, David Baker, and Alex Rives, moderated by Qian Cong and Parisa Hozzeinzadeh. Thank you to our Elite Sponsor Merck for supporting moments like this.

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Rosetta Commons @rosettacommons.bsky.social · 31/07/2026

A satellite event to European RosettaCon, the European Rosetta Workshop will take place on October 22-27 in Oeiras, Portugal. Participants, from all career stages, will get hands-on experience with the latest computational protein design methods using Rosetta and AI-based tools. zurl.co/AB2Ry

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Rosetta Commons @rosettacommons.bsky.social · 30/07/2026

Meet Qian! Qian’s lab is leveraging large-scale datasets, AI methods, and evolutionary principles to uncover protein functions, understand their roles in disease, and develop computational strategies for therapeutic discovery. Learn more about Qian in our July 2026 newsletter. zurl.co/gnlC6

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Rosetta Commons @rosettacommons.bsky.social · 27/07/2026

One week until Summer RosettaCon 2026! Virtual registration is open through August 6. Don’t miss our exciting lineup of speakers, including our invited speakers: Cameron Glasscock, Gye Rie Lee, Terra Sztain, and Martin Pacesa. Visit rosettacon.org to see the full scientific program and register.

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Rosetta Commons @rosettacommons.bsky.social · 23/07/2026

The IPD Women in Science would like to invite you to attend a social hour ahead of Summer RosettaCon at the Institute for Protein Design on UW's campus! This event is open to all conference attendees and locals and takes place on Aug 3 at 2:30 p.m. Please RSVP by Wed, July 29: zurl.co/ahfJJ

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Rosetta Commons @rosettacommons.bsky.social · 21/07/2026

A companion written tutorial is also available: rosettacommons.github.io/foundry/mode...

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Rosetta Commons @rosettacommons.bsky.social · 21/07/2026

Sometimes the hardest part of working with new tools is installing them. Watch this helpful tutorial to learn how to install RFDisffusion3 with Foundry so you can start experimenting with protein design today. www.youtube.com/watch?v=6rFE... #rcmegathon #rctutorial

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Rosetta Commons @rosettacommons.bsky.social · 16/07/2026

Thank you to our members, Anastassia Vorobieva and Helder Ribeiro, for organizing activities for these events. Read more at rosettacommons.org/news.

rosettacommons.org

News - Rosetta Commons

Explore the latest news from Rosetta Commons including science updates, learning resources, events, and more.

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Rosetta Commons @rosettacommons.bsky.social · 16/07/2026

In Spring 2026, the FEBS Advanced Practical Course on Generative AI for Protein Engineering was hosted in Belgium, where students participated in training on protein design pipelines. Then, CNPEM in Brazil hosted its annual Open Science Event introducing people to protein design through Foldit.

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Rosetta Commons @rosettacommons.bsky.social · 14/07/2026

RFdiffusion3 is a powerful tool for binder design. The newest tutorial from Rosetta Commons provides step-by-step guidance for how to design binders for simple proteins, small molecules, and proteins with post-translational modifications. www.youtube.com/watch?v=q1tS... #rcmegathon #rctutorial

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Rosetta Commons @rosettacommons.bsky.social · 09/07/2026

Meet Rosemary, Colter, Noah, James, and Callia. Combining computational and biological research in protein design, these talented undergraduates will be joining the Damo Lab, Gray Lab, IPD, Drew Lab, and Schoeder Lab to help solve challenges that impact health and environmental sciences. #REU26

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