Reposted by Rosenthal Lab for Pancreatic Cancer Research
I'm thrilled to share our latest research, published in Nature Communications. This work highlights how pancreatic cancer cells hijack cell polarity proteins to regulate macropinocytosis and tumor metabolism, shedding light on potential therapeutic vulnerabilities.
www.nature.com/articles/s41...
nature.com
Cell polarity proteins promote macropinocytosis in response to metabolic stress - Nature Communications
Cancer cells rely on macropinocytosis to survive in a nutrient-deprived environment. Here, Lambies et al. identified various members of the cell polarity protein network as essential regulators of mac...
