Reposted by Raimundo Freire
Pre-print Alert!
Spearheaded by @emilyshidalgo, RNF25 ubiquitin E3 activity modulates the three processes of the central dogma of Molecular Biology: DNA replication, Transcription and Translation by promoting the rapid degradation of different substrates
www.biorxiv.org/content/10.6...
biorxiv.org
RNF25 Ubiquitin E3 activity Safeguards Genome Integrity by Modulating DNA Replication, Transcription and Translation.
The human genome encodes several hundreds of ubiquitin E3 enzymes, most of which have poorly understood biological roles. In search for novel ubiquitin E3 enzymes involved in DNA damage tolerance, we ...
