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Renal and Urology News

@renalurologynews.bsky.social
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Clinical news for nephrologists and urologists.

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Renal and Urology News @renalurologynews.bsky.social · 22h
The @fda.gov has granted 510(k) clearance for SpaceOAR™ Flex Hydrogel by @bostonsci.bsky.social It's the latest iteration in #RectalSpacer technologies from the company. For more information, plus details from the study presented at #ASTRO26, click the link below🔽 bit.ly/4j8OOAl
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Renal and Urology News @renalurologynews.bsky.social · 11/10/2026
Starting SGLT2 inhibitors within 30 days of hospital discharge may decrease the risk of reaching end-stage kidney disease after acute kidney injury requiring dialysis. bit.ly/4yn7uR2
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Renal and Urology News @renalurologynews.bsky.social · 10/10/2026
A urine-based assay targeting AL021918.2 and vimentin methylation demonstrated 90.8% sensitivity and 93.2% specificity for #UrothelialCarcinoma detection according to a study published in @jamanetworkopen.com Read the full article here: bit.ly/4hEjpop
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Urine Methylation Assay Shows High Accuracy for Urothelial Carcinoma Detection
Various urine tests are showing promise for the diagnosis and surveillance of urothelial carcinoma, including bladder cancer and UTUC.
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Renal and Urology News @renalurologynews.bsky.social · 10/10/2026
Early vasopressors and restricted fluids do not improve 90-day outcomes in septic shock according to study findings from the New England Journal of Medicine @nejm.org See more study findings here: bit.ly/4hEm55r
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Renal and Urology News @renalurologynews.bsky.social · 09/10/2026
More from #ASTRO26! The PAM50 luminal B tumor status may be a biomarker to select ADT candidates among patients requiring salvage radiation for post-surgical detectable or rising PSA. Read more about this study here: bit.ly/4jQ3owO
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PAM50 May Guide ADT Use During Salvage Radiation for Recurrent Prostate Cancer
Trial investigators evaluated the prognostic and predictive ability of PAM50 molecular prostate cancer subtypes to guide salvage treatment.
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Renal and Urology News @renalurologynews.bsky.social · 08/10/2026
The PACE-A phase 3 trial presented at #ASTRO found the efficacy of stereotactic body radiotherapy for low- to intermediate-risk #ProstateCancer appears similar to radical prostatectomy Read more: bit.ly/4e1PPqv
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SBRT vs RP Shows Efficacy for Low- to Intermediate-Risk Prostate Cancer
PACE is the first phase 3 randomized trial directly comparing radical prostatectomy with SBRT in men with low- to intermediate-risk prostate cancer.
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Renal and Urology News @renalurologynews.bsky.social · 08/10/2026
The @fda.gov has granted 510(k) clearance for SpaceOAR™ Flex Hydrogel by @bostonsci.bsky.social It’s the latest iteration in #RectalSpacer technologies from the company. For more information, plus details from the study presented at #ASTRO26, click the link below🔽 bit.ly/4j8OOAl
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FDA Approves SpaceOAR Flex Hydrogel Rectal Spacer
Rectal spacers aim to minimize radiation exposure to the rectum during prostate cancer radiation therapy.
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Renal and Urology News @renalurologynews.bsky.social · 05/10/2026
Listen to @DrRenaMalik give advice on how other doctors and healthcare professionals can use social media wisely. Watch the full interview here: www.renalandurologynews.com/feature…
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Renal and Urology News @renalurologynews.bsky.social · 02/10/2026
We spoke with @DrRenaMalik about what inspired her to start using social media professionally. Watch the full interview here: www.renalandurologynews.com/feature…
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Renal and Urology News @renalurologynews.bsky.social · 01/10/2026
Who are some popular "medfluencers" that we think you should keep an eye on? Read our feature on social media influencers in urology: www.renalandurologynews.com/feature…
renalandurologynews.com
Urology Social Media Influencers Educate on GU Cancers, Sex, Surgery, Meds, and More
Popular “medfluencers” are using social media platforms to educate patients on urologic conditions, diseases, and men’s health.
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Renal and Urology News @renalurologynews.bsky.social · 01/10/2026
Dr. @RenaMalikMD talks to us about why she chose urology and how grateful she is to be working in her field. Watch the full interview here: www.renalandurologynews.com/feature…
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Renal and Urology News @renalurologynews.bsky.social · 29/09/2026
Starting SGLT2 inhibitors within 30 days of hospital discharge may decrease the risk of reaching end-stage kidney disease after acute kidney injury requiring dialysis. www.renalandurologynews.com/news/ac…
renalandurologynews.com
Early SGLT2i Initiation After AKI-Dialysis Cuts Kidney Events Risk in T2DM
Acute kidney injury (AKI) requiring dialysis is associated with higher risk of kidney failure, warranting risk mitigation.
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Renal and Urology News @renalurologynews.bsky.social · 28/09/2026
Apixaban vs warfarin was associated with less ischemic stroke and major bleeding among patients with atrial fibrillation and stage 4-5 CKD not on dialysis. www.renalandurologynews.com/news/ch…
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Apixaban vs Warfarin Appears Less Risky for Advanced CKD With AFib
A target trial emulation compared stroke and bleeding risks after apixaban vs warfarin in stage 4-5 chronic kidney disease with atrial fibrillation.
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Renal and Urology News @renalurologynews.bsky.social · 23/09/2026
Continuous Decipher score was associated with development of unfavorable histology following CAPRA adjustment (HR, 3.68). www.renalandurologynews.com/news/pr…
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Renal and Urology News @renalurologynews.bsky.social · 22/09/2026
PSMA radio-guided surgery can detect metastatic lymph nodes that are missed by preoperative PSMA PET in patients with intermediate- and high-risk prostate cancer. www.renalandurologynews.com/news/pr…
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PSMA-Radio-Guided Surgery Detects Additional Lymph Nodes in Prostate Cancer RARP
A phase 2 trial tested the ability of PSMA-radioguided surgery for detecting lymph node metastases in patients with intermediate- or high-risk prostate cancer.
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Renal and Urology News @renalurologynews.bsky.social · 18/09/2026
91% of men with a single GG2 prostate tumor treated with water therapy partial gland ablation showed GG1 or benign tissue in their 6-month MRI-targeted biopsy samples. www.renalandurologynews.com/news/gg…
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Early Outcomes of Water Vapor Tx Ablation for GG2 Prostate Cancer
Investigators reported initial results from the VAPOR 2 study, which assessed partial gland water vapor ablation in men with grade group 2 prostate cancer.
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Renal and Urology News @renalurologynews.bsky.social · 16/09/2026
Updated phase 2 trial data suggest efficacy and durability of first-line Gem/Doce in a small cohort of patients with BCG-naïve high-risk NMIBC. www.renalandurologynews.com/news/bl…
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Intravesical Gemcitabine and Docetaxel Appears Durable for BCG-Naïve, High-Risk NMIBC
A phase 2 open label trial tested intravesical gemcitabine and docetaxel as first-line treatment in patients with high-risk BCG-naïve nonmuscle-invasive bladder cancer.
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Renal and Urology News @renalurologynews.bsky.social · 15/09/2026
Combining donor urinary biomarkers (uromodulin, osteopontin, and chitinase-3–like protein 1) with KDPI may improve kidney graft assessment for transplantation vs discard. www.renalandurologynews.com/news/ki…
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Donor Urinary Biomarkers Improve Kidney Graft Outcome Prediction Beyond KDPI Alone
Combining donor urinary biomarkers (uromodulin, osteopontin, and chitinase-3–like protein 1) with KDPI may improve kidney graft assessment for transplantation vs discard. They can be measured rapidly ...
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Renal and Urology News @renalurologynews.bsky.social · 09/09/2026
Cardiologist referral improves cholesterol levels in patients newly diagnosed with prostate cancer. Whether it reduces cardiovascular events risk remains to be seen. www.renalandurologynews.com/news/pr…
renalandurologynews.com
Cardiovascular Care Referral Helps Select Men With Prostate Cancer
Cardiovascular risk factors should be addressed in men with prostate cancer, especially as they initiate androgen deprivation therapy (ADT).
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Renal and Urology News @renalurologynews.bsky.social · 08/09/2026
Experimental evidence suggests even short-term heat exposure during the day and especially at night during sleep can induce acute kidney stress. www.renalandurologynews.com/news/he…
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Renal and Urology News @renalurologynews.bsky.social · 04/09/2026
At 5 years, PFS was 91.4% in the 80 Gy group compared with 88.1% in the 70 Gy group. www.renalandurologynews.com/news/pr…
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GETUG-AFU 18: 80 Gy Dosing Prolonged PFS, OS in High-Risk Prostate Cancer
Investigators evaluated progression-free survival in men with high-risk prostate cancer assigned to dose-escalated radiotherapy plus long-term androgen deprivation therapy.
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Renal and Urology News @renalurologynews.bsky.social · 03/09/2026
At 12 months, the complete response rate was 36.7% in the supportive care group and 49.6% in patients who received immunosuppressive therapy. www.renalandurologynews.com/news/ri…
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Rituximab Improves CRR, Reduces Steroid Exposure in Lupus Membranous Nephropathy
A real-world study revealed little difference in 12-month renal response rates among immunosuppressive regimens for patients with first-onset PLMN.
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Renal and Urology News @renalurologynews.bsky.social · 01/09/2026
Cumulative incidence of metabolic syndrome increased steadily throughout the first year, peaking at 39.1%. www.renalandurologynews.com/news/me…
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MetS Rise Throughout First Year Post ADT+ARPI for Prostate Cancer
During the first year following treatment initiation, cumulative incidence of metabolic syndrome increased rapidly in this patient population.
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Renal and Urology News @renalurologynews.bsky.social · 31/08/2026
Renal-limited TMA occurred in nearly half of SLE cases and nearly all lupus nephritis cases in a single-institution cohort and requires kidney biopsy for diagnosis. www.renalandurologynews.com/news/th…
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Thrombotic Microangiopathy in SLE, Lupus Nephritis Characterized
Thrombotic microangiopathy (TMA) is a rare, but severe complication ofsystemic lupus erythematosus and lupus nephritis.
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Renal and Urology News @renalurologynews.bsky.social · 28/08/2026
Using a targeted biopsy-only approach for PI-RADS 3 lesions misses clinical significant prostate cancers in a large subset of men. www.renalandurologynews.com/news/pr…
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Systematic Biopsy Crucial After mpMRI-Targeted Prostate Biopsy for PI-RADS 3 Lesions
For men with equivocal PI-RADS 3 on multiparametric MRI, the added value of systematic biopsy after targeted biopsy has been debatable.
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Renal and Urology News @renalurologynews.bsky.social · 24/08/2026
Combination therapy remains the cornerstone of lupus nephritis treatment, but the field is moving toward individualizing treatment. www.renalandurologynews.com/news/kd…
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KDOQI Commentary on KDIGO Lupus Nephritis Guideline Offers Fresh Perspective
A KDOQI work group commented on the 2024 KDIGO guideline on lupus nephritis with some additional clinical tips.
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Renal and Urology News @renalurologynews.bsky.social · 21/08/2026
utDNA testing and dynamics accurately stratified risk of recurrence among study participants who received BCG for high-risk NMIBC. www.renalandurologynews.com/news/nm…
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Urine Tumor DNA May Forecast Recurrence Risk After BCG in High-Risk NMIBC
Urine tumor DNA may help distinguish which patients with non-muscle-invasive bladder cancer (NMIBC) are prone to recur.
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Renal and Urology News @renalurologynews.bsky.social · 19/08/2026
Contemporary US data on focal therapy use documents prostate cancer overtreatment in low-risk cases, and undertreatment in high-risk cases. www.renalandurologynews.com/news/ha…
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Half of Prostate Cancer Focal Therapy Cases Were Inappropriate
Investigators used the 2010-2023 National Cancer Database to identify US men with prostate cancer treated with focal therapy. Investigators used the 2010-2023 National Cancer Database to identify US m...
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Renal and Urology News @renalurologynews.bsky.social · 17/08/2026
Prolonged felzartamab in kidney transplant recipients reduced antibody-mediated rejection activity to a variable degree in an extension trial. www.renalandurologynews.com/news/fe…
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Prolonged Felzartamab May Sustain Control of Antibody-Mediated Kidney Transplant Rejection
Investigators conducted an extension study of the phase 2 trial of felzartamab in kidney transplant recipients.
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Renal and Urology News @renalurologynews.bsky.social · 14/08/2026
In a human pilot study, the Intilume system for robotic-assisted en bloc resection was successfully performed in 9 of 11 patients with suspected bladder tumors. www.renalandurologynews.com/news/bl…
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Robotic System Enables Transurethral En Bloc Bladder Tumor Resection
Transurethral robotic surgery may help urologists to successfully perform en bloc resection of bladder tumor.
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Renal and Urology News @renalurologynews.bsky.social · 10/08/2026
Renal tumor enucleation appears to preserve kidney function better than partial nephrectomy, but oncologic equivalence remains uncertain. www.renalandurologynews.com/news/ki…
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Tumor Enucleation vs Partial Nephrectomy May Better Preserve Renal Function in Kidney Cancer
The latest systematic review on kidney tumor enucleation vs partial nephrectomy includes robot-assisted series and randomized trials.
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Renal and Urology News @renalurologynews.bsky.social · 07/08/2026
Immunonutrition does not provide an added benefit against infection and other radical cystectomy complications over 30 and 90 days compared with a standard perioperative diet. www.renalandurologynews.com/news/ra…
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Immunonutrition Does Not Reduce 30-Day Radical Cystectomy Complications
A phase 3 randomized controlled trial tested specialized immunonutrition vs standard nutrition before radical cystectomy for bladder cancer.
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Renal and Urology News @renalurologynews.bsky.social · 06/08/2026
Kidney transplant candidates require wholistic, proactive nutritional care and metabolic support before they reach dysfunctional, problem states. Read our latest feature: www.renalandurologynews.com/feature…
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Optimizing Metabolic Health Before Kidney Transplantation
Kidney transplant candidates require wholistic, proactive nutritional care and metabolic support before they reach dysfunctional, problem states.
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Renal and Urology News @renalurologynews.bsky.social · 05/08/2026
At 10 years from HIFU or cryotherapy, few registry patients experienced prostate cancer progression or death. www.renalandurologynews.com/news/pr…
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Renal and Urology News @renalurologynews.bsky.social · 04/08/2026
In a phase 2 trial, adjuvant penpulimab vs observation was significantly associated with improved disease-free survival at 2 years after nephrectomy in patients with very-high risk ccRCC. www.renalandurologynews.com/news/as…
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PD-1 Blockade With Penpulimab May Prolong DFS in Asians With High-Risk ccRCC
A nonrandomized phase 2 trial tested penpulimab as adjuvant therapy in patients with very high risk renal cell carcinoma (RCC) after nephrectomy.
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Renal and Urology News @renalurologynews.bsky.social · 03/08/2026
A single dose of intravesical pirarubicin within 24 hours of RNU improved relapse-free survival over 3 years in patients with UTUC, and helped to prevent bladder recurrence. www.renalandurologynews.com/news/ut…
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Intravesical Pirarubicin After UTUC Surgery May Prolong Relapse-Free Survival
After showing early promise, a phase 3 trial tested intravesical pirarubicin after radical nephroureterectomy for upper tract urothelial carcinoma (UTUC).
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Renal and Urology News @renalurologynews.bsky.social · 30/07/2026
IgA nephropathy is more likely to develop in men vs women. Ramy Hanna, MD, of University of California, Irvine, discussed why and clinical implications. Read our latest feature: www.renalandurologynews.com/feature…
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Ramy Hanna, MD, Discusses IgA Nephropathy Prevalence in Men
IgA nephropathy is more likely to develop in men vs women. Ramy Hanna, MD, of University of California, Irvine, discussed why and clinical implications.
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Renal and Urology News @renalurologynews.bsky.social · 28/07/2026
Retroperitoneal robotic partial nephrectomy may be better for resecting posterior tumors. www.renalandurologynews.com/news/ki…
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Pentafecta Achievement Varies by Kidney Cancer Site, Partial Nephrectomy Approach
The choice between transperitoneal vs retroperitoneal surgical access for robotic partial nephrectomy may depend on the kidney cancer site.
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Renal and Urology News @renalurologynews.bsky.social · 27/07/2026
Urinary microbiomes differ between OAB and healthy states and by treatment response. These distinguishing markers may be used in future to improve diagnostics and therapeutics. www.renalandurologynews.com/news/ur…
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Urinary Microbiome Profiles May Distinguish Overactive Bladder, Treatment Responders
Study investigators compared the bacterial urinary microbiome in individuals with and without overactive bladder.
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Renal and Urology News @renalurologynews.bsky.social · 24/07/2026
Pop Quiz! How Would You Treat Blunt Abdominal Trauma? Test your knowledge now with our short clinical quiz: bit.ly/4hyCg4i #DiabetesMellitus
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Renal and Urology News @renalurologynews.bsky.social · 23/07/2026
A phase 3 trial published in European Urology Oncology found that among patients requiring post-radical prostatectomy (RP) radiation therapy (RT), RT timing has little effect on quality of life.✨ See all the data here: 🔗 bit.ly/3RTvOdQ #Urology
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Prostate Cancer Salvage vs Adjuvant Radiation Have Limited QOL Differences
The TROG 08.03 RAVES randomized controlled trial substudy examined quality of life after post-prostatectomy radiation therapy.
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Renal and Urology News @renalurologynews.bsky.social · 21/07/2026
Cognitive fusion biopsy performs best in lean men, whereas software-assisted targeted biopsy has diagnostic advantages in obese men. www.renalandurologynews.com/news/pr…
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Cognitive vs Software-Fusion Biopsy Noninferior for Prostate Cancer Detection
A trial of MRI-targeted prostate biopsy compared cognitive fusion and software-based fusion for detection of clinically significant prostate cancer.
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Renal and Urology News @renalurologynews.bsky.social · 18/07/2026
Listen to @DrMohitKhera talk about the appropriate patient for testosterone treatment. Watch our full interview here: www.renalandurologynews.com/feature… #testosterone
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Renal and Urology News @renalurologynews.bsky.social · 17/07/2026
Listen to @DrMohitKhera on FDA considerations for the treatment of testosterone. Watch our full interview here: www.renalandurologynews.com/feature… #testosterone
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Renal and Urology News @renalurologynews.bsky.social · 15/07/2026
The 8-hour bladder-kidney transplantation surgery was successful with good perfusion in both organs and led to unexpected normal bladder function. www.renalandurologynews.com/news/in…
renalandurologynews.com
In-Human Combined Bladder-Kidney Transplantation Feasible
Investigators describe the first human case of a dual bladder-kidney transplantation after terminal bladder disease and kidney failure.
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Renal and Urology News @renalurologynews.bsky.social · 14/07/2026
Early ASCVD screening at lupus nephritis diagnosis and annually thereafter are among the recommendations to mitigate risk. www.renalandurologynews.com/news/lu…
renalandurologynews.com
Panel Offers 13 Consensus Recs for ASCVD Risk Management in Lupus Nephritis
Atherosclerotic cardiovascular disease (ASCVD) risk is up to 9 times higher for patients with lupus nephritis vs systemic lupus erythematosus (SLE) alone.
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Renal and Urology News @renalurologynews.bsky.social · 10/07/2026
HPV-related cancers are more likely to occur in patients with HIV or a solid organ transplant — immunocompromised groups receiving long-term immunosuppressive regimens. www.renalandurologynews.com/news/hp…
renalandurologynews.com
HPV-Related Cancers More Likely in Organ Transplant Recipients, HIV
Human papillomavirus (HPV)-related cancers can cause substantial morbidity and mortality, and certain groups are more at risk.
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Renal and Urology News @renalurologynews.bsky.social · 08/07/2026
Pathologic complete response outperforms ctDNA clearance as an intermediate endpoint in neoadjuvant and perioperative immunotherapy trials. www.renalandurologynews.com/news/ct…
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Pathologic Complete Response vs ctDNA Remains Essential for Solid Cancer Prognostication
Investigators compared the prognostic value of pathologic vs molecular (ctDNA) complete response to immunotherapy across 8 tumor types.
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Renal and Urology News @renalurologynews.bsky.social · 06/07/2026
In trial participants with mild to moderate CKD and recent atrial fibrillation, antiarrhythmic drugs did not increase the risk for heart failure hospitalization, death, or stroke. www.renalandurologynews.com/news/ea…
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Early Rhythm vs Heart Rate Control Compared in CKD With AFib
Trial findings challenge concerns over early rhythm control in patients with mild to moderate chronic kidney disease (CKD) and recent atrial fibrillation.
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Renal and Urology News @renalurologynews.bsky.social · 01/07/2026
In a trial, letrozole significantly improved sperm concentration in men with spermatogenic failure compared with vitamin therapy alone. www.renalandurologynews.com/news/le…
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Letrozole Improves Sperm Count in Men With Spermatogenic Failure
The finding is from a Chinese randomized clinical trial testing letrozole in men with spermatogenic failure.
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