iiinova — where your digital self keeps evolving

Reposted by Richard Jenner

Jon Henninger @jhenninger.bsky.social · 08/06/2026

Excited to share the first pre-print from our lab!! Check it out here! www.biorxiv.org/content/10.6... We found that many RNA-binding proteins canonically understood to regulate RNA processing can also function like transcription factors and cofactors to directly regulate transcription.

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Richard Jenner @reggenomics.bsky.social · 27/05/2026

Does PRC2 interact with RNA or is it an artefact? See our preprint showing how stringent denaturing purifications with spike-in controls support direct interaction between PRC2 and RNA in cells. www.biorxiv.org/content/10.6...

UV-crosslinked human cells containing Halo-tagged EZH2 were mixed with crosslinked mouse cells in which the protein was untagged and human EZH2 purified with Halo resin. Enrichment of human RNA (left) or mouse RNA (right) versus input was plotted against RNA abundance in the paired input sample. Windows with significant enrichment (p <10−6; binomial test) are shown in red. Human RNAs show enrichment versus input whereas mouse RNAs do not.

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Reposted by Richard Jenner

Epigenetics Podcast @epigeneticspod.bsky.social · 13/02/2026

In this episode of the Epigenetics Podcast, we talked with Srinjan Basu from Imperial College London to talk about his work on how chromatin architecture and epigenetic mechanisms orchestrate developmental gene expression programs. #podcast #epigenetics Listen here: activemotif.com/podcasts-sri...

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Reposted by Richard Jenner

Rob Klose @robklose.bsky.social · 17/10/2025

We are recuiting two new Associate Professors here in Oxford Biochemistry. Come join us! Reach out to me if you have any questions. Please repost! tinyurl.com/mr3m7bd3

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Richard Jenner @reggenomics.bsky.social · 10/10/2025

Interested in applying your molecular biology skills to improve tumour #immunotherapy? @cruk-cityoflondon.bsky.social #PhD studentship available in my lab @ucl.ac.uk in collaboration with @diunguyenvnuk.bsky.social @qmbci.bsky.social For more information and to apply: colcc.ac.uk/phd-students...

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