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Reproductive BioMedicine Online @rbmonline.bsky.social · 8h

Many women recover spontaneous ovarian function and fertility after OTC, while for those who do not, subsequent OTT offers a possibility of restoring both menstruation and fertility, confirming OTC/OTT as an effective long-term strategy for fertility preservation. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 29/09/2026

We are LIVE! with International IVF Initiative for our 17th webinar. Nico Garrido and Sandro Esteves welcome a huge international audience to our session tonight – from USA, Spain, Brazil, Jordan, Egypt, Canada, Jamaica, Nigeria, Madagascar, India, Turkey, Iraq, Greece, UK….and many more!

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Reproductive BioMedicine Online @rbmonline.bsky.social · 29/09/2026

This review examines how automation may be integrated into IVF laboratories through a set of conceptual distinctions, with the aim of improving consistency and laboratory capacity, while preserving clinical responsibility, trust in automation, and professional satisfaction. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 28/09/2026

This new study demonstrates that continuous dienogest administration led to a significant decrease in endometrioma diameter and volume over follow-up, with the highest reduction observed within the first 6 months of treatment. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 25/09/2026

For female same-sex couples, IUI alone had a similar success rate to IUI with ovarian stimulation. In women aged <35 years, >50% are likely to achieve pregnancy after six IUI cycles, but in those aged ≥35 years, alternative fertility treatment should be expedited. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 25/09/2026

The results in this new study suggest that congenital uterine anomalies (CUA) may be associated with a less favourable implantation environment and early gestational adaptation, with the most consistent adverse findings observed in septate uterus. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 24/09/2026

This review synthesizes over 20 years of research, through January 2025, into endometrial scratch techniques, examining whether methodological variations explain conflicting outcomes and assessing the clinical significance of reported benefits. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 24/09/2026

This new paper from an international group of authors is one of the most comprehensive investigations demonstrating the impact of a systematic internal audit system on embryological and clinical outcomes in IVF laboratories. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 23/09/2026

Join us for next live webinar next week, Tuesday 29th, with Nico Garrido, Sandro Esteves, Sarah Martins da Silva and Ahmad Metwalley discussing on the latest advances and guidance in sperm standards and male infertility management Follow the link for full details sh1.sendinblue.com/3g3ej2855z9p...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 23/09/2026

The results presented by Laura Melado and co-authors in this paper may provide valuable complementary information on follicular sensitivity during ovarian stimulation. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 23/09/2026

This paper details how microchimerism can be detected in menstrual blood, with data showing its presence in all groups of women, irrespective of group or parity. Published open access, the full paper is available from the Periconception section of our November issue, now: doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 22/09/2026

This new Commentary strives towards collaboration between neurologists, endocrinologists and immunologists to ensure reproduction in MS would no longer be only a matter of protecting fertility, but an opportunity to better understand the biology of the disease itself. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 22/09/2026

This study demonstrates the success of using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) combined with machine learning, to accurately classify embryos by ploidy status using spent embryo culture media (SECM). doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 21/09/2026

This new Review article provides an updated overview of the effects of chemotherapy on the ovary, and summarize current and emerging gonadoprotective strategies doi.org/10.1016/j.rb... Chemotherapy #Fertility

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Reproductive BioMedicine Online @rbmonline.bsky.social · 21/09/2026

This new paper presents the first US study to report on the pregnancy outcomes from fast vitrification protocols in the setting of both standard warming and fast warming protocols - adding to the literature supporting the adoption of fast vitrification and warming protocols. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 18/09/2026

This is the first study to systematically detail the regulatory role and molecular mechanism of pyruvate carboxylase in the progression of endometriosis, indicating a role as both a biomarker and a potential therapeutic target for endometriosis. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 18/09/2026

In women with infertility and in those who have experienced RPL or RIF, diffuse adenomyosis involving the inner myometrial layer was associated with a significantly higher prevalence of chronic endometritis in this cohort. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 17/09/2026

Reproductive BioMedicine Online invite you to the 17th edition of our quarterly webinar series, in this special session with our andrology editors and special guest speakers. Register now, and read this thread for more details! bit.ly/RBMOlive17 1/6

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Reproductive BioMedicine Online @rbmonline.bsky.social · 17/09/2026

The wave motion quantification approach developed by Sania Latif and her research team, showcased in this new paper, provides an objective, reproducible method for assessing uterine peristalsis on TVS. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 17/09/2026

This systematic review discusses the impacts of idiopathic premature ovarian insufficiency on pregnancy, and emphasize the need for well-designed future studies in this field. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 16/09/2026

The preliminary findings in this new study shows that endometriosis is associated with a distinct follicular fluid steroid profile during ovarian stimulation, and may contribute to the infertility associated with the condition. doi.org/10.1016/j.rb... #FemaleReproductiveHealthAndFertility

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Reproductive BioMedicine Online @rbmonline.bsky.social · 15/09/2026

In this new Countercurrent contribution, Maria Longo and Antonio La Marca discuss conceptual, biological, and clinical issues around the renaming of polycystic ovary syndrome (PCOS) to “Polyendocrine Metabolic Ovarian Syndrome” (PMOS). doi.org/10.1016/j.rb... RBMOcountercurrent #PCOS #PMOS

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Reproductive BioMedicine Online @rbmonline.bsky.social · 15/09/2026

This large retrospective cohort study of more than 1000 fresh embryo transfers found no association between embryo exposure time to a hyaluronic acid-enriched transfer medium (EmbryoGlue) and live birth rates. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 14/09/2026

This new study supports the clinical adoption of quantitative hormonal monitoring for patients attempting to conceive and provide the validation needed for expanded research into personalized reproductive health management. The full paper is available open access, now: doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 11/09/2026

This study compares six commercial AI ploidy algorithms across 1000 PGT-A-validated blastocysts. Though one system was developed explicitly for ploidy prediction, all algorithms displayed a similar pattern of euploidy enrichment across higher score strata. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 11/09/2026

This scoping review aims to synthesise existing evidence, identify gaps in the literature and propose a committee opinion on 2.1PN zygotes, including a working provisional definition, to guide clinical practice and future studies. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 10/09/2026

This new study reassure patients undergoing multiple planned oocyte cryopreservation cycles that a second ovarian stimulation immediately or up to 180 days after the first oocyte retrieval is not inferior to an intercycle interval of 29–90 days. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 10/09/2026

Despite growing evidence, the contribution of paternal factors to embryo morphokinetics and clinical outcomes has been largely overlooked. This new new review highlights the influence of sperm characteristics on later-stage embryonic development, implantation and live birth doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 09/09/2026

Here’s RBMO Editor Nick Macklon in a short clip from our 'Submission Masterclass' episode of RBMO Live. He provides a set of six questions to ask yourself to guide the structure of an effective manuscript Watch the full video on our YouTube channel: youtube.com/shorts/M0qcg... #AcademicWriting

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Reproductive BioMedicine Online @rbmonline.bsky.social · 09/09/2026

This new study finds disturbances in calcium homeostasis are associated with poorer semen quality and reproductive hormonal profile, and should be routinely evaluated as part of the andrological work-up in men referred with infertility. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 08/09/2026

The study provides an opportunity to discuss the current recommendation against using AMH in conjunction with USG for PCOS diagnosis in symptomatic women, where identifying these patients enables earlier metabolic intervention, potentially outweighing overdiagnosis risks. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 08/09/2026

This new study highlights the importance of targeted seminal exosome treatments for different spermatozoa, providing valuable insights for developing personalized approaches in this field. RBMO subscribers can read the full paper ahead of press from our October issue now: doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 07/09/2026

This new meta-analysis uses real-world data to address key challenges in establishing reliable evidence on long-term health and developmental outcomes in children conceived using conventional IVF or ICSI. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 07/09/2026

Let’s start the week with Issue 53.3 of RBMO! Our September issue features 28 papers, with original research, reviews, Fertility Freefall special issue papers, Commentaries and an Editorial on our work developing RBMO's social media presence and community. www.rbmojournal.com/issue/S1472-...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 03/09/2026

Both clinicians and scientists may benefit from the findings of this new review, which clarifies current strategies and highlights next-generation solutions for preserving and restoring the fertility of young female patients. | doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 02/09/2026

This new review analyses eight studies (totalling 1,904 mosaic and 9,332 euploid transfers),and concludes mosaic embryo transfer can be offered with individualized counselling and evidence-based prioritization when no euploid alternatives are available doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 01/09/2026

This new study shows that changes in placental endocannabinoid signalling (ECS) are largely determined by developmental stage, with spontaneous preterm birth reflecting an earlier phase of these processes rather than a distinct pathological state. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 28/08/2026

This paper provides further support for the development of machine learning software in enhancing the efficiency and accuracy of ART, assisting in embryo selection and providing personalized treatment recommendations. The full paper is available open access, now doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 27/08/2026

This new systematic review and meta-analysis provides novel evidence of a significant association between adenomyosis and chronic endometritis (CE), suggesting that women with adenomyosis have a markedly higher risk of CE compared with those without. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 27/08/2026

The results of this new study support organizational flexibility for fresh embryo transfers in IVF laboratories, and may help laboratories prioritize workflow efficiency without compromising clinical success. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 26/08/2026

This new study investigates improvements to patient experience and the measurements of key reproductive hormones during IVF monitoring using the microblade-based self-collection device Tasso+ (Tasso, USA). doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 26/08/2026

This is the first study to report a possible association between endometrial dysbiosis, chronic endometritis, and specific Killer-cell Immunoglobulin-like Receptor (KIR) genes/regions, offering new perspectives for personalized reproductive medicine. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 25/08/2026

The TransFertility project is a systematic demonstration that trans-inclusive fertility preservation is achievable. The authors call on professional bodies and policymakers to engage with this evidence and develop coordinated clinical pathways to improve equitable provision doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 21/08/2026

The findings in this new study have important implications for interpreting PGT-A results and the counselling patients of advanced maternal age who are undergoing fertility preservation and oocyte accumulation strategies. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 21/08/2026

This new systematic review suggests that higher maternal BMI may adversely affect several periconceptional outcomes, with the most consistent evidence observed for miscarriage. The Review is published open access, available ahead of press from issue 53.4 now: doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 20/08/2026

Have you read the latest edition of RBMO Insights? Issue 51 features a profile with Section Editor Rossella Cannarella, recent videos on our YouTube, three new Talking Points and testimonials from recent authors on the science editing o their papers sh1.sendinblue.com/3g2xo8w55z9p...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 20/08/2026

This new systematic review explores whether the clomiphene citrate stair-step protocol (SSP) for ovulation induction in patients with polycystic ovary syndrome (PCOS) outperforms the traditional protocol. Read it in full or free, now: doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 19/08/2026

The Summer 2026 edition of RBMO Digest is here! Catch up with the biggest papers from recent issues of the journal, with our regular round up of Hot Topics, Editor’s Choice, Review Articles and more Read it in pdf form or from our website sh1.sendinblue.com/aompkw55z9pf... #RBMOdigest

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Reproductive BioMedicine Online @rbmonline.bsky.social · 19/08/2026

In this new Commentary, @alessandra-alteri.bsky.social and colleagues propose a cautious but proactive framework to translate the emergent science on the integration of morphological assessment with validated genetic testing into clinical benefits. doi.org/10.1016/j.rb...

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Reproductive BioMedicine Online @rbmonline.bsky.social · 18/08/2026

This prospective, randomized, proof-of-concept trial provides preliminary evidence from sibling donor oocytes to support the feasibility of a simplified vitrification and warming protocol for oocyte cryopreservation. doi.org/10.1016/j.rb...

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