Reposted by @ravijanagal.bsky.social
Happy to share our recent work published in #Genetics! Ravi previously showed that thiol reductive stress activates the hypoxia response (HIF-1) pathway. Now he shows that the HIF-1 pathway protects from thiol stress via an acyltransferase. @genetics-gsa.bsky.social
academic.oup.com/genetics/adv...
academic.oup.com
Protection from thiol reductive stress through an autoinhibitory hypoxia response pathway in Caenorhabditis elegans
Abstract. Cellular redox homeostasis depends on a finely tuned balance between oxidizing and reducing conditions, and disturbances in this balance lead to