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Ravi Radhakrishnan

@ravi-radhak.bsky.social
8 followers 2 following 1 posts

Science, Engineering, Medicine Nerd, Outdoors, Travel, Art Enthusiast, Husband, Parent of 3 children (two 2-legged and one 4-legged)

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Ravi Radhakrishnan @ravi-radhak.bsky.social · 20/09/2025
Excited and grateful to @upenn.edu Engineers for covering our lab! blog.seas.upenn.edu/penn-enginee...
blog.seas.upenn.edu
Penn Engineers Explore How Tumor Mechanics and Tiny Messengers Could Shape the Future of Cancer Research - Penn Engineering Blog
When Ph.D. student Kshitiz Parihar began combing through dozens of research papers on two seemingly different topics — tumor mechanics and extracellular vesicles, tiny packages … Read More ›
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Reposted by Ravi Radhakrishnan
Nature Cancer @natcancer.nature.com · 15/04/2025
Online today! Wei Guo and team show that, in response to CAR T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferred to CAR T cells, resulting in fratricide and reduced antitumor activity. www.nature.com/articles/s43...
nature.com
Overcoming extracellular vesicle-mediated fratricide improves CAR T cell treatment against solid tumors - Nature Cancer
Zhong et al. show that, in response to chimeric antigen receptor (CAR) T cell targeting, solid tumors increase the secretion of small extracellular vesicles carrying tumor antigens that are transferre...
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