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Raiees Andrabi @raieesandrabi.bsky.social · 14/04/2026

Excited to share our new paper in @cp-immunity.bsky.social showing that "Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques" A promisingstep toward an HIV vaccine advancing soon to human clinical testing! Immunity www.cell.com/immunity/ful...

cell.com

Germline-targeting HIV immunogen induces cross-neutralizing antibodies in outbred macaques

Inducing broadly neutralizing antibodies (bnAbs) remains a challenge in HIV vaccine development. Mishra et al. show that an engineered germline-targeting HIV trimer, Q23-APEX-GT2, primes rare V2-apex ...

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Reposted by Raiees Andrabi

Hensley Lab @scottehensley.bsky.social · 22/02/2026

Our preprint examining the specificity of human antibodies that cross-react with subclade K H3N2 viruses was posted this morning on medRxiv. These studies have implications on what vaccine strains should be selected for next year’s influenza season. 1/ www.medrxiv.org/content/10.6...

medrxiv.org

Mapping the specificity of H3N2 strain-specific and cross-reactive human neutralizing antibodies elicited by the 2025-2026 influenza vaccine

An H3N2 variant, named subclade K, continues to circulate widely during the 2025-2026 influenza season. This virus possesses a hemagglutinin (HA) protein that has eleven substitutions relative to the ...

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Reposted by Raiees Andrabi

Bloom lab @jbloomlab.bsky.social · 20/02/2026

We have posted data providing real-time measurement of human neutralizing antibody landscape to seasonal influenza. Data explain spread of subclades K (H3N2) & D.3.1.1 (H1N1), identify subclade K subvariants w reduced neutralization, & can inform choice of strains for next vaccine.

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Raiees Andrabi @raieesandrabi.bsky.social · 15/02/2026

Now peer-reviewed at @sciimmunology.bsky.social Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development | Science Immunology www.science.org/doi/10.1126/...

science.org

Env-antibody coevolution identifies B cell priming as the principal bottleneck to HIV V2 apex broadly neutralizing antibody development

B cell priming is a primary bottleneck to HIV-1 V2 apex bNAb elicitation.

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Raiees Andrabi @raieesandrabi.bsky.social · 09/07/2025

In our new study, we show that several pre-Omicron RBD bnAbs still neutralize highly mutated SARS-CoV-2 variants. Structures reveal conserved, vaccine-targetable epitopes that resist extreme antigenic drift, highlighting promising targets for pan-sarbecovirus vaccines www.cell.com/cell-reports...

cell.com

Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift

Identifying and understanding the molecular basis of conserved spike epitopes targeted by broadly neutralizing antibodies (bnAbs) are key for developing broad coronavirus vaccine design. Song et al. r...

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