Excited to share my preprint describing a new microbiome analysis method, PHLAME, for detecting strain-level associations in difficult sample types. 🧵
www.biorxiv.org/content/10.1...
This work was done with my great coauthors and my amazing advisor @contaminatedsci.bsky.social
biorxiv.org
Intraspecies associations from strain-rich metagenome samples
Genetically distinct strains of a species can vary widely in phenotype, reducing the utility of species-resolved microbiome measurements for detecting associations with health or disease. While metage...