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Psychedelic Science & Policy

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Psychedelic Science and Policy from across the open internet

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Psychedelic Science & Policy @psysci.pyxorium.com · 03/06/2026
Vicente Webinar | Colorado Goes Further: Ibogaine, HB 26-1325, and Key Changes to the NMHA Thursday, Jun 4, 2026 01:30 pm
us02web.zoom.us
Welcome! You are invited to join a webinar: Ibogaine in Colorado: HB 26-1325 Research Pilot Program, Licensing & Natural Medicine Health Act Update. After registering, you will receive a confirmation ...
Colorado’s HB 26-1325 is the most significant expansion of the state’s natural medicine program since the Natural Medicine Health Act first became law. The bill establishes an ibogaine research pilot...
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Psychedelic Science & Policy @psysci.pyxorium.com · 14/04/2026
Exciting news, Psychedelic Science returning to Denver for the 2027 conference
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Psychedelic Science & Policy @psysci.pyxorium.com · 05/02/2026
Colorado Public Radio's Kiara DeMare reports on state-licensed psychedelic healing centers in Colorado.
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Psychedelic Science & Policy @psysci.pyxorium.com · 01/11/2025
Monday, November 17, 2025, 1:00-2:00pm (PT) webinar "As promising clinical trial data for substances like psilocybin and MDMA emerges, a critical question remains: how should these compounds move from Schedule I of the Controlled Substances Act to become accessible medical treatments?"
law.berkeley.edu
After Schedule I: Federal Psychedelic Rescheduling and the Impact on State Law
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Psychedelic Science & Policy @psysci.pyxorium.com · 15/10/2025
Webinar Monday, October 20, 2025 10AM Eastern Dr. Bill Detmer, CEO of Unbound Medicine, hosts Dr. Paul Nestadt and Dr. Mary Elizabeth “Bit” Yaden from the Johns Hopkins School of Medicine for a discussion on the evolving field of psychedelic medicine.
us06web.zoom.us
Webinar Registration - Zoom
Dr. Bill Detmer, CEO of Unbound Medicine, hosts Dr. Paul Nestadt and Dr. Mary Elizabeth “Bit” Yaden from the Johns Hopkins School of Medicine for a discussion on the evolving field of psychedelic medicine. Their conversation will explore practical strategies for patient education and innovative approaches to expanding mental health care capacity. Attendees will gain actionable insights to navigate emerging treatments and support informed conversations with patients. A live Q&A will follow the discussion.
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Psychedelic Science & Policy @psysci.pyxorium.com · 05/09/2025
"In the present study, the magnitude of the [Oceanic Boundlessness] experience induced by [high ventilation breathwork with music] was comparable to that elicited by serotonergic psychedelic substances, including psilocybin and lysergic acid diethylamide (LSD)" Aug 2025 PLoS One 20(8): e0329411
journals.plos.org
Neurobiological substrates of altered states of consciousness induced by high ventilation breathwork accompanied by music
The popularity of breathwork as a therapeutic tool for psychological distress is rapidly expanding. Breathwork practices that increase ventilatory rate or depth, facilitated by music, can evoke subjec...
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Psychedelic Science & Policy @psysci.pyxorium.com · 02/09/2025
Starting in October 2025, the US Department of Defense will test Service members for psilocin (psilocybin mushroom) consumption due to "the risk of impairment and subsequent deterioration of security, military fitness, readiness, good order and discipline" (per linked DOD Memorandum)
sofx.com
Service Members to Be Tested for Hallucinogenic Psilocin Found in ‘Magic Mushrooms’
The Pentagon will begin testing service members for psilocin, the hallucinogenic compound produced when psilocybin mushrooms, also known as magic
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Alliance for a Better Utah @betterutah.bsky.social · 07/08/2025
A Utah-based faith group is suing for the right to use psilocybin mushrooms as part of its religious practices, arguing that criminalization violates religious freedom protections. The case could set a significant precedent in balancing state drug laws with religious liberty.
buff.ly
Judges rules in favor of Utah faith group seeking to use psychedelic mushrooms
The first-of-its-kind case is putting Utah’s new religious freedom law to the test
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Psychedelic Science & Policy @psysci.pyxorium.com · 12/08/2025
State psychedelic legalization and policy roundup, August 2025 Arizona, Colorado, Louisiana, Massachusetts, Michigan, Mississippi, Oregon
reason.org
State psychedelics legalization and policy roundup — August 2025
Arizona allocates funding for ibogaine research, Reason Foundation to testify at Mississippi informational hearing about ibogaine, and more.
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Psychedelic Science & Policy @psysci.pyxorium.com · 07/08/2025
"[P]articipants reported improvements in their sleep, physical ability, cognitive function, social ability, fatigue, anxiety, and the impact of pain on their everyday lives. Three months later, researchers found [...] the reductions around the impacts of pain became statistically insignificant."
klcc.org
Oregon study shows psilocybin therapy helped low-income people fight depression
Psilocybin therapy can help low-income people suffering from depression, according to a new study from Oregon researchers.
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Psychedelic Science & Policy @psysci.pyxorium.com · 07/08/2025
"Our study hints at an exciting avenue for future research to combine neuromodulation with psychedelics to precisely target specific circuits for neural plasticity." bioRxiv 2025 August
biorxiv.org
Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks
Psilocybin holds promise as a treatment for mental illnesses. One dose of psilocybin induces structural remodeling of dendritic spines in the medial frontal cortex in mice. The dendritic spines would ...
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Psychedelic Science & Policy @psysci.pyxorium.com · 06/08/2025
Dr. Lawrence Leeman of the University of New Mexico describes how the REKINDLE clinical trial will test the effectiveness of RE104 (a synthetic prodrug similar to psilocybin) in treating patients who have received a life-altering disease diagnosis.
hscnews.unm.edu
UNM Scientists Test Experimental Psychedelic Drug to Alleviate the Emotional Toll of a Life-Threatening Diagnosis
University of New Mexico researchers are joining a multi-site clinical trial of an experimental psychedelic drug intended to alleviate the mental suffering many patients experience when they receive a...
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Olson Lab @deolsonlab.bsky.social · 05/08/2025
Check out our latest paper in Nature Neuroscience (rdcu.be/ey7yk). This was a great collaboration with some very surprising results! Seems that a glutamate burst and proximate IEG expression might not be necessary for structural neuroplasticity induced by 5-HT2A partial agonists.
rdcu.be
The psychoplastogen tabernanthalog induces neuroplasticity without proximate immediate early gene activation
Nature Neuroscience - Aarrestad et al. show that, in contrast to psychedelics, the nonhallucinogenic psychoplastogen tabernanthalog promotes neuroplasticity through 5-HT2AR activation without...
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Institute for Psychedelics and Neurotherapeutics @ucdavisipn.bsky.social · 05/08/2025
Greg Watry of @ucdlands.bsky.social wrote a wonderful article about the #UCDavisIPN's @natureportfolio.nature.com most recent Neuroscience publication. Find out why our associate director, John A. Gray said, "Science is full of surprises." Read the article here: www.ucdavis.edu/news/psyched...
ucdavis.edu
Psychedelics and Non-hallucinogenic Analogs Work Through the Same Receptor, Up to a Point
Understanding exactly how psychedelics promote new connections in the brain is critical to developing targeted, non-hallucinogenic therapeutics that can treat neurodegenerative and neuropsychiatric di...
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Psychedelic Science & Policy @psysci.pyxorium.com · 05/08/2025
"With growing attention towards psilocybin treatment, the associated risk of medical liability for physicians involved in prescribing psilocybin or facilitating psilocybin treatment becomes increasingly important to study." J Law Med Ethics 2025 July
cambridge.org
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Psychedelic Science & Policy @psysci.pyxorium.com · 03/08/2025
"Psychedelics such as LSD and DMT, have shown intriguing results in regulating neuroplasticity and inflammation, but their use in [Alzheimer's disease] treatment is still largely experimental and requires rigorous clinical validation." Transl Neurodegener. 2025 July
translationalneurodegeneration.biomedcentral.com
Psychoactive substances: novel molecular insights and therapeutic potential for Alzheimer's disease - Translational Neurodegeneration
Alzheimer's disease (AD) is a major neurodegenerative disorder that causes severe cognitive decline and poses a significant burden on global health systems. Despite extensive research, effective treat...
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Psychedelic Science & Policy @psysci.pyxorium.com · 01/08/2025
"Filament Health has collaborated with University College London (UCL) in the UK to provide its botanical psilocybin drug candidate, PEX010, for two Phase II research studies."
clinicaltrialsarena.com
Filament Health to supply psilocybin for two Phase II studies
Filament Health has collaborated with UCL to provide its botanical psilocybin drug candidate, PEX010, for two Phase II research studies.
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Psychedelic Science & Policy @psysci.pyxorium.com · 31/07/2025
Inside Appalachia producer Bill Lynch speaks with Corinne Hazel and Daniel Panaccione about their research on fungi in morning glory plants that make psychedelic ergot alkaloids.
wvpublic.org
WVU Researcher Discovers Potential Mental Health Treatment Through Psychedelic Fungi - West Virginia Public Broadcasting
A West Virginia researcher is working at the cutting edge of the study of psychedelics. Corinne Hazel is a West Virginia University microbiology student. This spring, she found a fungus that was barel...
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Psychedelic Science & Policy @psysci.pyxorium.com · 31/07/2025
Alana Hippensteele analyzes issues relevant to psychedelic health care professionals, such as informed consent, standard of care, licensing, data collection, HIPAA conflicts, cybersecurity, breach liability, insurance coverage and reimbursement, and more.
ajmc.com
The Legal Architecture of Psychedelic Therapy: Risks, Responsibilities, and Reimbursement Realities
Key legal, ethical, and compliance considerations for managed care professionals navigating the evolving landscape of psychedelic-assisted therapy include regulatory risks, data privacy challenges, re...
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profdavidnutt.bsky.social @profdavidnutt.bsky.social · 31/07/2025
www.drugscience.org.uk/uk-governmen... - light at the end of the tunnel for #psychedelics research and treatment we hope
drugscience.org.uk
UK Government supports ACMD plan to enable research with schedule 1 medicines such as psilocybin and MDMA
Despite the resurgence of research into the clinical efficacy and mechanism of action of psychedelic drugs such as such as psilocybin, LSD, DMT, and MDMA they are currently in Schedule 1 of the Misuse...
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Psychedelic Science & Policy @psysci.pyxorium.com · 30/07/2025
Dr. Jhilam Biswas speaks on behalf of the Massachusetts Psychiatric Society to express the Society's support for decriminalizing the simple possession of psilocybin.
marijuanamoment.net
Massachusetts Psychiatric Society Endorses Bill To Decriminalize Psilocybin Possession
“We are encouraged by the growing body of rigorous research exploring the use of psychedelics, including psilocybin in treating treatment-resistant types of mental illness.” By Jack Gorsline, HorizonM...
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Michael Pollan @michaelpollan.bsky.social · 28/07/2025
(29) The Molly Maker: 5 Questions for PharmAla founder Nick Kadysh themicrodose.substack.com/p/the-molly-...
themicrodose.substack.com
The Molly Maker: 5 Questions for PharmAla founder Nick Kadysh
Kadysh discusses PharmAla’s MDMA and the logistics of the international MDMA supply chain.
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Drugreporter @drugreporter.bsky.social · 29/07/2025
Watch three exciting book presentations that Drugreporter recorded at PS25 in Denver, by Timothy Leary’s son, Zach Leary, Wendy Tucker, Ann Shulgin’s daughter and Diego Ugalde.
drogriporter.hu
Extraordinary Books at Psychedelic Science 2025
Watch three exciting book presentations that Drugreporter recorded at PS25 in Denver. Timothy Leary’s son, Zach Leary, presented his new book Your Extraordinary Mind; Wendy Tucker, Ann Shulgin’s daugh...
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Psychedelic Science & Policy @psysci.pyxorium.com · 29/07/2025
"Whether these therapies live up to their billion-dollar potential in mental health and beyond may depend less on the molecules themselves, and more on the industry’s ability to deliver them safely, ethically and at scale." European Medical Journal, 2025 July
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Psychedelic Science & Policy @psysci.pyxorium.com · 28/07/2025
"Together, these findings indicate that LSD, acutely administered, acts as a rapid-onset antidepressant in naïve rat, but not in naïve mice, through mechanisms involving activation of 5-HT2B receptors." Biomedicine & Pharmacotherapy 2025
sciencedirect.com
LSD's rapid antidepressant effects are modulated by 5-HT2B receptors
Recent clinical trials show that serotonergic psychedelics, including the prototypical hallucinogen lysergic acid diethylamide (LSD), possess a great …
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UCL Centre for Consciousness Research @uccr.bsky.social · 24/07/2025
Two psilocybin studies led by @rosmcalpine.bsky.social, @mjaglinska.bsky.social, @kjedlovszky.bsky.social, @orisshenyan.bsky.social, and others. www.filament.health/news/filamen...
filament.health
Filament Health Announces Two Phase 2 Research Trials In Partnership With University College London
Filament Health Announces Two Phase 2 Research Trials In Partnership With University College London
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Earl K. Miller @earlkmiller.bsky.social · 25/07/2025
A psychedelic drug disorganizes cortical traveling waves. Groovy work. Complex slow waves in the human brain under 5-MeO-DMT doi.org/10.1016/j.ce... #neuroscience
doi.org
Redirecting
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Psychedelic Science & Policy @psysci.pyxorium.com · 27/07/2025
Avon, Colorado approves rules for psilocybin healing centers "The town’s regulations on natural medicine healing centers will go into effect 30 days following the July 22 approval, at which point natural medicine businesses can begin to open in Avon." report by @vaildaily.bsky.social
vaildaily.com
Psychedelic therapy centers can open in Avon beginning in August
Therapeutic centers that use psychedelic compounds to treat patients will be able to open in Avon beginning in August. On Tuesday, Avon finished establishing where and under what limitations natural m...
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Psychedelic Science & Policy @psysci.pyxorium.com · 25/07/2025
Dr. Manesh Girn describes how psychedelic therapy can help with depression by overcoming isolation and restoring connection, healing trauma and emotional wounds, and enhancing flexible thinking.
youtube.com
3 Ways Psychedelics Treat Depression
YouTube video by The Psychedelic Scientist
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Filter | harm reduction journalism @filtermag.bsky.social · 23/07/2025
Colorado’s Natural Medicine Advisory Board is now weighing this historic move, with the governor's support. Ibogaine has shown promise for SUD and other conditions, reports Alexander Lekhtman, though safety risks post some pratical and ethical questions:
filtermag.org
Ibogaine Clinics Closer Than Ever in Colorado
The Natural Medicine Advisory Board is weighing this, with the governor's support. The drug shows therapeutic promise, along with some risks.
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Alaina Jaster, PhD @jasteralaina.bsky.social · 23/07/2025
Check out my keynote & Day 1 dispatch of #GRCPsychedelics 🧠 via @psychedelicalpha.bsky.social psychedelicalpha.com/news/dispatc...
psychedelicalpha.com
Dispatch: The Neurobiology of Psychedelics Gordon Research Conference — Plasticity, Psychotherapy, and Perception (Part 1) - Psychedelic Alpha
Here, we share Dr. Alaina Jaster’s observations from the inaugural Neurobiology of Psychedelics Gordon Research Conference, where leading scientists gathered to explore various realms of psychedelic…
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Psychedelic Science & Policy @psysci.pyxorium.com · 24/07/2025
"Our findings suggest that classic psychedelics are widely used by individuals with a lived experience of an ED and that this naturalistic use of psychedelics is self-reported as having positive outcomes on ED symptoms and general mental health." J Eat Disord 2025 July
jeatdisord.biomedcentral.com
Psychedelic use in individuals living with eating disorders or disordered eating: findings from the international MED–FED survey - Journal of Eating Disorders
Background There are few effective treatments for eating disorders (EDs), and new interventions are urgently needed. The MEDication and other drugs For Eating Disorders (“MED–FED”) survey investigated...
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Psychedelic Science & Policy @psysci.pyxorium.com · 23/07/2025
"[T]he use of artistic elements depicting the natural world may be an effective entry point to create connections with psychedelic dosing settings that are comfortable for individuals that have no prior engagement with any psychedelic group, subculture, or microclimate." Scientific Reports 2025 July
nature.com
Quantitative and qualitative influences of spiritual connection and natural imagery on perception of art in clinical psychedelic dosing settings - Scientific Reports
Scientific Reports - Quantitative and qualitative influences of spiritual connection and natural imagery on perception of art in clinical psychedelic dosing settings
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Psychedelic Science & Policy @psysci.pyxorium.com · 22/07/2025
"[T]he enduring experiences afforded by psilocybin as a psychophysical adaptogen may help to shift individual perspectives, thereby permitting individuals to initiate or reengage with their rehabilitation efforts from a place of equanimity and purpose." J. Pain 2025 July
sciencedirect.com
Psilocybin as a Psychophysical Adaptogen in Chronic Pain Rehabilitation
Those living with chronic pain and comorbid functional disabilities are often confronted by a physically and emotionally transformative experience, im…
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The Colorado Sun ☀️ @coloradosun.com · 21/07/2025
Colorado plans for rollout of ibogaine as the next regulated psychedelic plant medicine in healing centers
coloradosun.com
Colorado plans for rollout of ibogaine as the next regulated psychedelic plant medicine in healing centers
Regulators plan to integrate ibogaine treatment into Colorado’s psychedelic healing industry. Still, the drug faces an uncertain future.
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Psychedelic Science & Policy @psysci.pyxorium.com · 21/07/2025
"Psilocybin and ayahuasca retreats significantly improved veterans’ mental well-being, quality of life, PTSD, anxiety, depression, sleep, concussion, and post-deployment reintegration." Brain Behav. 2025 July
pubmed.ncbi.nlm.nih.gov
Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings - PubMed
This is the first study to investigate psychedelic retreats as a holistic therapy for veterans' mental health alongside community reintegration. Psilocybin and ayahuasca retreats significantly improve...
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Psychedelic Science & Policy @psysci.pyxorium.com · 20/07/2025
"The Czech Senate has approved a major reform of the country’s criminal code, including a significant shift in drug policy. Key changes include [...] the medical legalization of [psilocybin] mushrooms."
english.radio.cz
Czechia moves toward regulated drug use with cannabis and psilocybin changes
The Czech Senate has approved a major reform of the country’s criminal code, including a significant shift in drug policy. We discuss it with drug expert  Jindřich Vobořil.
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Psychedelic Science & Policy @psysci.pyxorium.com · 20/07/2025
Dr. Jack (Giancarlo) Allocca discusses the concept of bodyset, and the use of 5-MeO-DMT as a catalyst for inducing altered states to "serve as a biological 'reboot,' disrupting entrenched patterns and catalyzing deep physiological transformation." from @mind-foundation.bsky.social
youtube.com
The Consciousness Reboot: Using Extreme Altered States to Reset Mental and Physical Health
YouTube video by MIND Foundation
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Psychedelic Science & Policy @psysci.pyxorium.com · 19/07/2025
"[W]e investigated the pharmacological profile of 41 psychedelic drugs across tryptamine, phenethylamine, and lysergamide chemical classes against 318 G-protein-coupled receptors (GPCRs) and found that many psychedelics potently activated serotonin, dopamine, and adrenergic receptors."
sciencedirect.com
The polypharmacology of psychedelics reveals multiple targets for potential therapeutics
The classical psychedelics (+)-lysergic acid diethylamide (LSD), psilocybin, and mescaline exert their psychedelic effects via activation of the 5-HT2…
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Nate Heller @nate-h-heller.bsky.social · 17/07/2025
🌈🧠 The Trip Between Bedside and Bench 🌈🧠 Join us at #SfN2025 for a deep dive into cross-species research in psychedelic neuroscience! 🧬 Posters, 🎤 panels, 🔑 keynotes, 🍸 cocktails, and 🥟 tasty apps await. RSVP, explore speaker profiles, and help spread the word: 👉 hopkinspsychedelic.org/sfn2025
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Psychedelic Science & Policy @psysci.pyxorium.com · 18/07/2025
"This study demonstrates that the aesthetic quality of psychedelic experiences may be a crucial factor in predicting positive psychological outcomes, corroborating claims that subjective experience is necessary for psychedelic-induced therapeutic effects."
frontiersin.org
Frontiers | Aesthetic quality of psychedelic experience is linked to insight and psychological outcomes
IntroductionThe aesthetic qualities of psychedelic experiences have long been documented, but their specific contribution to therapeutic outcomes remains und...
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Jennifer Yvette Brown @jenniferyvette.bsky.social · 17/07/2025
Psychedlic Science 2025 session videos are live! For free! Share and Enjoy. virtualtrip.maps.org?utm_medium=e...
virtualtrip.maps.org
MAPS Virtual Trip
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Psychedelic Science & Policy @psysci.pyxorium.com · 17/07/2025
"The [NMHA] made legal in Colorado something that Indigenous cultures have considered traditional for centuries. Santiago Guerra, a professor of Southwest Studies at Colorado College [...] says the roll out of the new law is a chance to build connections with Indigenous expertise."
cpr.org
Colorado's new psychedelics law draws attention to natural medicine's Indigenous roots | Colorado Public Radio
The Natural Medicine Act made legal in Colorado something that Indigenous cultures have considered traditional for centuries. Santiago Guerra, a professor of Southwest Studies at Colorado College who ...
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International Alliance of Mental Health Research Funders @iamhrf.bsky.social · 11/07/2025
Can psychedelics deliver on their promise for mental health? 📰 New expert commentary on the future of #psychedelics as a treatment for #mentalhealth conditions is now live on @thementalelf.bsky.social! Read: lnkd.in/di6RCREb We'd love to hear from you - comment below to continue the discussion⤵️
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Reality Sandwich @reality-sandwich.bsky.social · 16/07/2025
Kyle Rosner shares a behind-the-scenes look at MAPS Psychedelic Science 2025, including the two-night Psychedelic Playhouse and the high-stakes Psych-Tank pitch.
realitysandwich.com
From Panels to Playhouse: Recapping Psychedelic Science 2025
Kyle Rosner shares a behind-the-scenes look at MAPS Psychedelic Science 2025, including the two-night Psychedelic Playhouse and the high-stakes Psych-Tank pitch.
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Psychedelic Science & Policy @psysci.pyxorium.com · 16/07/2025
Researchers usually don't run clinical trials for medication safety during pregnancy, but instead look to reporting systems or data registries. This article refers to a community research paper exploring the safety of psilocybin in perinatal care, bridging Indigenous knowledge with western science.
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Psychedelic Science & Policy @psysci.pyxorium.com · 15/07/2025
"In June, Texas Republican Governor Greg Abbott signed legislation that will provide up to $50 million dollars to research ibogaine, a psychoactive compound derived from the iboga shrub native to Central West Africa."
americanhomefront.wunc.org
Texas is the latest state to embrace psychedelic therapy research for mental health treatment
A new Texas law that will provide up to $50 million to study ibogaine reflects growing government interest in psychedelic therapy research for mental health treatments
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Alaina Jaster, PhD @jasteralaina.bsky.social · 14/07/2025
Someone asked at #GRCPsychedelics how we can bridge science and policy, especially in red states. Support and join organizations like SSDP and AAAS. Write op-Ed’s for local newspapers. Set up hill days for your lab to educate lawmakers. Attend city council meetings. Make public comments.
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Psychedelic Science & Policy @psysci.pyxorium.com · 13/07/2025
"[Morgan] Luttrell is among a growing group of Republican lawmakers - many of them veterans - who are making the case for [Schedule I drugs like ibogaine, psilocybin and MDMA] that they say help address issues like PTSD, depression and substance abuse."
luttrell.house.gov
Lawmaker ‘Reborn’ Through Psychedelic Therapy Wants the GOP to Embrace It
Morgan Luttrell says he had never smoked anything, let alone tried drugs in his life. So the retired Navy SEAL had to ask a nearby nurse for guidance on how to inhale a psychedelic drug that was part ...
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Alaina Jaster, PhD @jasteralaina.bsky.social · 11/07/2025
The Neurobiology of Psychedelics GRC is next week!! I will be there in a different capacity than normal… if you’re interested in being interviewed about your science, the current climate of research in psychedelics, or anything else please find me! Also if anyone is hiring - let’s chat 😁
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